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| 1 | Gastric emptying, postprandial blood pressure, glycaemia and splanchnic flow in Parkinson's disease显示文摘AIM: To determine gastric emptying, blood pressure, mesenteric artery blood flow, and blood glucose responses to oral glucose in Parkinson's disease. METHODS: Twenty-one subjects(13 M, 8 F; age 64.2 ± 1.6 years) with mild to moderate Parkinson's disease(Hoehn and Yahr score 1.4 ± 0.1, duration of known disease 6.3 ± 0.9 years) consumed a 75 g glucose drink, labelled with 20 MBq 99mTc-calcium phytate. Gastric emptying was quantified with scintigraphy, blood pressure and heart rate with an automated device, superior mesenteric artery blood flow by Doppler ultrasonography and blood glucose byglucometer for 180 min. Autonomic nerve function was evaluated with cardiovascular reflex tests and upper gastrointestinal symptoms by questionnaire. RESULTS: The mean gastric half-emptying time was 106 ± 9.1 min, gastric emptying was abnormally delayed in 3 subjects(14%). Systolic and diastolic blood pressure fell(P < 0.001) and mesenteric blood flow and blood glucose(P < 0.001 for both) increased, following the drink. Three subjects(14%) had definite autonomic neuropathy and 8(38%) had postprandial hypotension. There were no significant relationships between changes in blood pressure, heart rate or mesenteric artery blood flow with gastric emptying. Gastric emptying was related to the score for autonomic nerve function(R = 0.55, P < 0.01). There was an inverse relationship between the blood glucose at t = 30 min(R =-0.52, P < 0.05), while the blood glucose at t = 180 min was related directly(R = 0.49, P < 0.05), with gastric emptying. CONCLUSION: In mild to moderate Parkinson's disease, gastric emptying is related to autonomic dysfunction and a determinant of the glycaemic response to oral glucose. | Laurence G Trahair Thomas E Kimber Katerina Flabouris Michael Horowitz Karen L Jones | 2016 | World Journal of Gastroenterology2016，22，20： | 5 |
| 2 | Haploid Angiosperms显示文摘 | Kimber G Riley R | 1963 | Botanical Review1963，29，： | 1 |
| 3 | Giemsa C-banding and the evolution of wheat显示文摘 | Gill B S Kimber G | 1974 | Proc Nat Acad Sci(USA)1974，71，： | 1 |
| 4 | Giemsa C-banding and the evolution of wheat显示文摘 | Gill B S Kimber G | 1974 | Proc Natl Acad Sci USA1974，71，： | 1 |
| 5 | The distribution of Vallisneria americana seeds and seedling light requirements in the upper Mississippi River显示文摘 | Korschgen C E van der Valk A G | 1995 | Can J Bot1995，73，： | 1 |
| 6 | Reinvestigation of the S genome in Triticum kotschyi显示文摘 | Yen Y Kimber G | 1990 | Genome1990，33，： | 1 |
| 7 | Leukocyte subpopulations in the uteri of leukemia inhibitory factor knockout mice during early pregnancy显示文摘 | Schofield G Kimber ST | 2005 | Biol Reprod2005，72，4： | 1 |
| 8 | Mode of formation of 3,4 - benzopyrene in human envi- ronment 显示文摘 | BADGER G M KIMBER R W L SPOTSWOOD T M | 1960 | Nature1960，187，： | 1 |
| 9 | Serologic survey of selected viral agents in recently captured wild North American river otters (Lontra canadensis)显示文摘 | Kimber K R Kollias G V Dubovi E J | 2000 | J Zoo Wildl Med2000，31，： | 1 |
| 10 | Haploid angiosperms 显示文摘 | Kimber G Riley R | 1963 | Bol Rev1963，29，： | 1 |
| 11 | The giemsa C bandcal karyotype of ry显示文摘 | Gill B S Kimber G | 1974 | Proc Natl Acad Sci USA1974，71，： | 1 |
| 12 | Toxicogenetics: Applications and opportunities显示文摘 | Orphanides G Kimber T | 2003 | Toxicol Sci2003，75，： | 1 |
| 13 | Leukocyte subpopulations in the uteri of leukemia inhibitory factor knockout mice during early pregnancy显示文摘 | SCHOFIELD G KIMBER S J | 2005 | Biol Reprod2005，72，4： | 1 |
| 14 | FMRFamide-related peptides in potato cyst nematodes 显示文摘 | Kimber M J Fleming C C Bjourson A J Hahon D W Maule A G | 2001 | Molecular and Biochemical Parasitology2001，116，： | 1 |
| 15 | FMRFamide-related peptides in potato cyst nematodes 显示文摘 | Kimber M J Fleming C C Bjourson A J Hahon D W Maule A G | 2001 | Molecular and Biochemical Parasitology2001，116，： | 1 |
| 16 | tip gene disruption in a parasitic nematode reveals motor dysfunction and unusual neuronal sensitivity to RNA interference 显示文摘 | Kimber M J McKinney S McMaster S Day T A Fleming C C Maule A G | 2007 | The Faseb Journal2007，21，： | 1 |
| 17 | Theileria annulata:cross-reactions between a cell culture schizont antigen and antigens of East African species in the indirect fluorescent antibody test显示文摘 | BURRIDGE M J BROWN C G KIMBER C D | 1974 | Exp Parasitol1974，35，3： | 1 |
| 18 | Localisation of Globodera pallida FMRFamide-related peptide encoding genes using in situ hybridization显示文摘 | Kimber M J Fleming C C Prior A Jones J T Halton D W Maule A G | 2002 | International Journal for Parasitology2002，32，： | 1 |
| 19 | Fabrication of carbon fibre composites for gas separation 显示文摘 | Kimber G M Jagtoyen M | 1996 | Gas Separation & Purification1996，10，2： | 1 |
| 20 | Recognition of translocations and alien chromosome transfer in wheat by the Giemsa C-banding technique显示文摘 | Gill B S Kimber G | 1977 | Crop Science1977，17，： | 1 |
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