5篇
您的检索式：作者名="Kimberly Wilson"
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| 1 | Immunity:研究开发出最优的HIV疫苗递送模式显示文摘HIV已不再占据头条新闻。这主要是因为抗逆转录病毒药物的成功开发已将HIV病毒感染导致的艾滋病(AIDS)转化为一种慢性的可控制的疾病。然而。当前在全世界大约0.367亿名HIV感染者中,仅约一半的人能够获得控制这种病毒所需的药物。与此同时。新的HIV感染率持续保持在非常高的水平,这突出强调了需要开发一种预防性疫苗。然而,几十年来。 | Matthias Pauthner Colin Havenar-Daughton Devin Sok Joseph P. Nkolola Raiza Bastidas Archana V. Boopathy Diane G. Carnathan Abishek Chandrashekar Kimberly M. Cirelli Christopher A. Cottrell Alexey M. Eroshkin Javier Guenaga Kirti Kaushik Daniel W. Kulp Jinyan Liu Laura E. McCoy Aaron L. Oom Gabriel Ozorowski Kai W. Post Shailendra K. Sharma Jon M. Steichen Steven W. de Taeye Talar Tokatlian Alba Torrents de la Peña Salvatore T. Butera Celia C. LaBranche David C. Montefiori Guido Silvestri Ian A. Wilson Darrell J. Irvine Rogier W. Sanders William R. Schief Andrew B. Ward Richard T. Wyatt Dan H. Barouch Shane Crotty Dennis R. Burton | 2017 | 现代生物医学进展2017，17，27： | 2 |
| 2 | A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen显示文摘 | Xiao-Jun Ma Zuncai Wang Paula D Ryan Steven J Isakoff Anne Barmettler Andrew Fuller Beth Muir Gayatry Mohapatra Ranelle Salunga J.Todd Tuggle Yen Tran Diem Tran Ana Tassin Paul Amon Wilson Wang Wei Wang Edward Enright Kimberly Stecker Eden Estepa-Sabal Ba | 2004 | Cancer Cell2004，，6： | 1 |
| 3 | A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen显示文摘 | Xiao-Jun Ma Zuncai Wang Paula D Ryan Steven J Isakoff Anne Barmettler Andrew Fuller Beth Muir Gayatry Mohapatra Ranelle Salunga J.Todd Tuggle Yen Tran Diem Tran Ana Tassin Paul Amon Wilson Wang Wei Wang Edward Enright Kimberly Stecker Eden Estepa-Sabal Ba | 2004 | Cancer Cell2004，，6： | 1 |
| 4 | Behavior management techniques among pediatric dentists practicing in the southeastern United States显示文摘 | Carr Kimberly R Wilson Stephen Nimer Sue | 1999 | Pediatric Dentistry1999，21，6： | 1 |
| 5 | Nutrient-regulated dynamics of chondroprogenitors in the postnatal murine growth plate显示文摘Longitudinal bone growth relies on endochondral ossification in the cartilaginous growth plate,where chondrocytes accumulate and synthesize the matrix scaffold that is replaced by bone.The chondroprogenitors in the resting zone maintain the continuous turnover of chondrocytes in the growth plate.Malnutrition is a leading cause of growth retardation in children;however,after recovery from nutrient deprivation,bone growth is accelerated beyond the normal rate,a phenomenon termed catch-up growth.Although nutritional status is a known regulator of long bone growth,it is largely unknown whether and how chondroprogenitor cells respond to deviations in nutrient availability.Here,using fate-mapping analysis in Axin2CreERT2 mice,we showed that dietary restriction increased the number of Axin2+chondroprogenitors in the resting zone and simultaneously inhibited their differentiation.Once nutrient deficiency was resolved,the accumulated chondroprogenitor cells immediately restarted differentiation and formed chondrocyte columns,contributing to accelerated growth.Furthermore,we showed that nutrient deprivation reduced the level of phosphorylated Akt in the resting zone and that exogenous IGF-1 restored the phosphorylated Akt level and stimulated differentiation of the pooled chondroprogenitors,decreasing their numbers.Our study of Axin2CreERT2 revealed that nutrient availability regulates the balance between accumulation and differentiation of chondroprogenitors in the growth plate and further demonstrated that IGF-1 partially mediates this regulation by promoting the committed differentiation of chondroprogenitor cells. | Takeshi Oichi Joe Kodama Kimberly Wilson Hongying Tian Yuka Imamura Kawasawa Yu Usami Yasushi Oshima Taku Saito Sakae Tanaka Masahiro Iwamoto Satoru Otsuru Motomi Enomoto-Iwamoto | 2023 | Bone Research2023，11，2： | 0 |
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