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| 1 | Therapeutic advances: Single incision laparoscopic hepatopancreatobiliary surgery显示文摘Single-port laparoscopic surgery(SPLS) is proposed to be a step towards minimizing the invasiveness of surgery, and has since gained popularity in several surgical sub-specialties including hepatopancreatobiliary surgery. SPLS has since been applied to cholecystectomy, liver resection as well as pancreatectomy for a multitude of pathologies. Benefits of SPLS over conventional multi-incision laparoscopic surgery include improved cosmesis and potentially post-operative pain at specific time periods and extra-umbilical sites. However, it is also associated with longer operating time, increased rate of complications, and increased rate of port-site hernia. There is no significant difference between length of hospital stay. SPLS has a significant learning curve that affects operating time, rate of conversion and rate of complications. In this article, we review the literature on SPLS in hepatobiliary surgery- cholecystectomy, hepatectomy and pancreatectomy, and offer tips on overcoming potential technical obstacles and minimizing the complications when performing SPLS- surgeon position, position of port and instruments, instrument crossing position, standard hand grip vs reverse hand grip, snooker cue guide position, prevention of incisional hernia. SPLS is a promising direction in laparoscopic surgery, and we recommend step-wise progression of applications of SPLS to various hepatopancreatobiliary surgeries to ensure safe adoption of the surgical technique. | Stephen Kin Yong Chang Kai Yin Lee | 2014 | World Journal of Gastroenterology2014,20,39: | 8 |
| 2 | Comparative study and systematic review of laparoscopic liver resection for hepatocellular carcinoma显示文摘AIM: To compare the surgical outcomes between laparoscopic liver resection(LLR) and open liver resection(OLR) as a curative treatment in patients with hepatocellular carcinoma(HCC). METHODS: A Pub Med database search was performed systematically to identify comparative studies of LLR vs OLR for HCC from 2000 to 2014. An extensive text word search was conducted, using combinations of search headings such as 'laparoscopy', 'hepatectomy', and 'hepatocellular carcinoma'. A comparative study was also performed in our institution where we analysed surgical outcomes of 152 patients who underwent liver resection between January 2005 to December 2012, of which 42 underwent laparoscopic or hand-assisted laparoscopic resection and 110 underwent open resection. RESULTS: Analysis of our own series and a review of 17 high-quality studies showed that LLR was superior to OLR in terms of short-term outcomes, as patients in the laparoscopic arm were found to have less intraoperative blood loss, less blood transfusions, and a shorter length of hospital stay. In our own series, both LLR and OLR groups were found to have similar overall survival(OS) rates, but disease-free survival(DFS) rates were higher in the laparoscopic arm. CONCLUSION: LLR is associated with better short-term outcomes compared to OLR as a curative treatment for HCC. Long-term oncologic outcomes with regards to OS and DFS rates were found to be comparable in both groups. LLR is hence a safe and viable option for curative resection of HCC. | Wei Qi Leong Iyer Shridhar Ganpathi Alfred Wei Chieh Kow Krishnakumar Madhavan Stephen Kin Yong Chang | 2015 | World Journal of Hepatology2015,7,27: | 7 |
| 3 | Risk factors of positive surgical margin and biochemical recurrence of patients treated with radical prostatectomy: a single-center 10-year report显示文摘许多研究显示出的背景那积极外科的边缘和生物化学的复发能影响病人的生活,前列腺癌症与激进的前列腺切除术对待。与有前列腺的越来越多的病人一起,癌症出现了在最近在中国的 20 年,调查积极外科的边缘的风险是必要的,生物化学的复发,和他们病人的预后上的可能的影响与基一起对待前列腺切除术。在这研究,我们与前列腺癌症分析了病人的特征在澳门区域经历了激进的前列腺切除术并且试着发现有从有前列腺癌症的 2000~2009,149 个病人的这些 patients.Methods 的预后的积极外科的边缘和生物化学的复发和他们的关系的任何风险因素收到了激进的前列腺切除术并且是的人,跟随了 up.Among 这些病人们, 111 收到的 retropubic 激进分子前列腺切除术, 38 收到的 laparoscopic 激进分子 prostatectomie 在每后续任何抱怨的一个详细记录,浆液前列腺特定的抗原(PSA ) ,完整的生物化学的测试和 uroflowmetry 是 acquired.Results 平均年龄(69.0 景汯?? | LI Kin LI Hong YANG Yong Ian Lap-hong Pun Wai-hong Ho Son-fat | 2011 | Chinese Medical Journal2011,,7: | 7 |
| 4 | Lycium barbarum extract promotes M2 polarization and reduces oligomeric amyloid-β-induced inflammatory reactions in microglial cells显示文摘Lycium barbarum(LB)is a traditional Chinese medicine that has been demonstrated to exhibit a wide variety of biological functions,such as antioxidation,neuroprotection,and immune modulation.One of the main mechanisms of Alzheimer’s disease is that microglia activated by amyloid beta(Aβ)transform from the resting state to an M1 state and release pro-inflammatory cytokines to the surrounding environment.In the present study,immortalized microglial cells were pretreated with L.barbarum extract for 1 hour and then treated with oligomeric Aβfor 23 hours.The results showed that LB extract significantly increased the survival of oligomeric Aβ-induced microglial cells,downregulated the expression of M1 pro-inflammatory markers(inducible nitric oxide synthase,tumor necrosis factorα,interleukin-6,and interleukin-1β),and upregulated the expression of M2 anti-inflammatory markers(arginase-1,chitinase-like protein 3,and interleukin-4).LB extract also inhibited the oligomeric Aβ-induced secretion of tumor necrosis factorα,interleukin-6,and interleukin-1βin microglial cells.The results of in vitro cytological experiments suggest that,in microglial cells,LB extract can inhibit oligomeric Aβ-induced M1 polarization and concomitant inflammatory reactions,and promote M2 polarization. | Zhong-Qing Sun Jin-Feng Liu Wei Luo Ching-Hin Wong Kwok-Fai So Yong Hu Kin Chiu | 2022 | Neural Regeneration Research2022,17,1: | 4 |
| 5 | CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development显示文摘尽管 HCO 3− 被知道为早胚胎开发被要求,它的准确角色留下逃犯。这里,我们报导 HCO 3− 在在 preimplantation 胚胎开发期间通过调停 CFTR 的流入调整 miR-125b 表示充当环境暗示。结果证明在 preimplantation 胚胎开发的 HCO 3− 的效果能被介入压制一条 HCO 3−-conducting 隧道的函数, CFTR,由一个特定的禁止者或基因大美人。细胞外的 HCO 3− 的移动或 CFTR 的抑制在 2 个房间阶段老鼠胚胎减少 miR-125b 表示。miR-125b 击倒模仿 HCO 3− 移动和 CFTR 抑制的效果,当 miR-125b 先锋的注射颠倒它时。在人和老鼠胚胎的 miR-125b upregulates p53 串联的 Downregulation。miR-125b 的激活被显示被 sAC/PKA-dependent 调停 NF-κ 的原子 shuttling; B。这些结果在在 preimplantation 胚胎开发期间连接环境 HCO 3− 到 miR-125b 的激活的信号 transduction 揭示了 CFTR 的一个关键角色并且在 miRNAs 的规定显示了离子隧道的重要性。 | Yong Chao Lu Hui Chen Kin Lam Fok Lai Ling Tsang Mei Kuen Yu Xiao Hu Zhang Jing Chen Xiaohua Jiang Yiu Wa Chung Alvin Chun Hang Ma Anskar Yu Hung Leung He Feng Huang Hsiao Chang Chan | 2012 | Cell Research2012,22,10: | 2 |
| 6 | Pulsatilla Saponin D:the antitumor principle from Pulsatilla koreana显示文摘 | Kin Yong Bang S C Lee J H | 2004 | Arch Pharm Res2004,27,9: | 1 |
| 7 | The kinematic Error Bound Analysis of the Stewart Platform 显示文摘 | Han Kin S Yong Chol J | 2000 | Journal of Robotic System2000,17,1: | 1 |
| 8 | Interim report: A randomized controlled trial comparing postoperative pain in single‐incision laparoscopic cholecystectomy and conventional laparoscopic cholecystectomy显示文摘 | Stephen Kin Yong Chang Yi Liang Wang Liang Shen Shridhar Ganpathi Iyer Ahmad Bin Syed Buhari Shaik Davide Lomanto | 2012 | Asian J Endosc Surg2012,,1: | 1 |
| 9 | Single‐incision laparoscopic hepatic resection in patients with previous hepatic resections: A mini case series显示文摘 | Guowei Kim Arthur Chin‐Haeng Lau Stephen Kin Yong Chang | 2014 | Asian J Endosc Surg2014,,1: | 1 |
| 10 | Volatile compounds in fermented and acid-hydrolyzed soy sauce显示文摘 | Lee S M Seo B C Kin Yong Suk | | 0,,03: | 1 |
| 11 | Thermally Stable Nanocrystalline TiO2 Photocatalysts Synthesized via Sol-gel Methods Modified with Ionic Liquid and Surfactant Molecules 显示文摘 | Hyeok Choi Yong Jin Kin Rajender S Varma | 2006 | Chemistry of Materials2006,18,22: | 1 |
| 12 | Sonography for Right Lower Quadrant Pain显示文摘 | Yong Sun Kin M D Yongsoo Kin M D On Koo Cho M D | 2001 | J Clinical Ultrasound2001,29,3: | 1 |
| 13 | Effects of Carbon Content of Carbon Steel on its Dissolution into a Molten Aluminum AHoy 显示文摘 | Sung Ha Hwang Jin Hwa Song Yong Suk Kin | 2005 | Materials Science and Engineering2005,390,: | 1 |
| 14 | Effects of the ethyl acetate fraction of Spatholobi caulis on tumorcell aggregation and migration显示文摘 | In-Cheol kang Seung-Ae kin Cyu Yong Song | 2003 | Phytotherapy Research2003,17,2: | 1 |
| 15 | Effect of high density polyethylene addition and testing temperature on the mechanical and morphological properties of polypropylene/ethylene-propylenediene terpolymer binary binary blends显示文摘 | Ju Yong Kin Byoung Chul Chun | 2000 | Journa of Materials Science2000,35,: | 1 |
| 16 | Experimental study of thefatigue behavior of high strength concrete 显示文摘 | Jin - Keun Kin Yun - Yong Kim | 1996 | Cement&Concrete Research1996,26,10: | 1 |
| 17 | Production of pullulan by a fed-batch fermentation 显示文摘 | SHIN Yong Chul KIN Young Ho LEE Hyun Soo | 1987 | Biotechnology Letters1987,9,9: | 1 |
| 18 | Circulation of solids and gas bypassing in an internally circulating fluidized bed with a draft tube显示文摘 | Byung Ho Song Yong Tag Kin Sang Done Kim | 1997 | Chemical Engineering Journal1997,68,: | 1 |
| 19 | Modeling of frost growth and frost properties with air flow over a flat plate 显示文摘 | Yun Rin Kim Yong Chan Min Man Kin | 2002 | International Journal of Refrigeration2002,25,3: | 1 |
| 20 | Overexpression and simple purification of human superoxide dismutase (SOD1) in yeast and its resistance to oxidative stress显示文摘 | Hae Yong Yoo Shin Seog Kin Hyune Mo Rho | 1999 | Journal of Biotechnology1999,68,: | 1 |