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| 1 | Clinical importance of colonoscopy in patients with gastric neoplasm undergoing endoscopic submucosal dissection显示文摘AIM To evaluate the usefulness of total colonoscopy(TCS) for patients undergoing gastric endoscopic submucosal dissection(ESD) and to assess risk factors for colorectal neoplasms.METHODS Of the 263 patients who underwent ESD at our department between May 2010 and December 2013, 172 patients undergoing TCS during a one-year period before and after ESD were targeted. After excluding patients with a history of surgery or endoscopic therapy for colorectal neoplasms, 158 patients were analyzed. Of the 868 asymptomatic patients who underwent TCS during the same period because of positive fecal immunochemical test(FIT) results, 158 patients with no history of either surgery or endoscopic therapy for colorectal neoplasms who were matched for age and sex served as the control group for comparison.RESULTS TCS revealed adenoma less than 10 mm in 53 patients(33.6%), advanced adenoma in 17(10.8%), early colorectal cancer in 5(3.2%), and advanced colorectalcancer in 4(2.5%). When the presence or absence of adenoma less than 10 mm, advanced adenoma, and colorectal cancer and the number of adenomas were compared between patients undergoing ESD and FITpositive patients, there were no statistically significant differences in any of the parameters assessed. The patients undergoing ESD appeared to have the same risk of colorectal neoplasms as the FIT-positive patients. Colorectal neoplasms were clearly more common in men than in women(P = 0.031). Advanced adenoma and cancer were significantly more frequent in patients with at least two of the following conditions: hypertension, dyslipidemia, and diabetes mellitus(P = 0.019).CONCLUSION In patients undergoing gastric ESD, TCS appears to be important for detecting synchronous double neoplasms. Advanced adenoma and cancer were more common in patients with at least two of the following conditions: hypertension, dyslipidemia, and diabetes mellitus. Caution is therefore especially warranted in patients with these risk factors. | Chieko Tsuchida Naoto Yoshitake Hitoshi Kino Yoshihito Kaneko Masakazu Nakano Kohei Tsuchida Keiichi Tominaga Takako Sasai Hironori Masuyama Hidetsugu Yamagishi Yasuo Imai Hideyuki Hiraishi | 2017 | World Journal of Gastroenterology2017,23,23: | 3 |
| 2 | Glucocorticoids and their actions: an introduction显示文摘 | Charmandari E Kino T Chrousos G P | 2004 | Arm N Y Acad Sci2004,1024,: | 1 |
| 3 | Noise analysis of an air-core fiber optic gyroscope显示文摘 | Blin S Digonnet M J F Kino G S | 2007 | IEEE Photonics Technology Letters2007,19,19: | 1 |
| 4 | 显示文摘 | FUJIMOTO C KINO J SAWADA H | 1995 | J Chromatogr: A1995,716,12: | 1 |
| 5 | Glucocorticoid receptor mu-tants demonstrate increased motility inside the nucleus of living cells:time of fluorescence recovery after photobleaching(FRAP)is an inte-grated measure of receptor function显示文摘 | Kino T Liou SH Charmandari E | 2004 | Mol Med2004,10,: | 1 |
| 6 | Discovery of FK506, a noval immunosupprasant isolated from streptomyces tsukubaensis 显示文摘 | Goto T Kino T Halanaka H | 1987 | Transplant Proc1987,19,1: | 1 |
| 7 | Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster:potential physiological implications显示文摘 | Nader N Chrousos G P Kino T | 2009 | FASEB J2009,23,5: | 1 |
| 8 | Clinico-statistical study of temporomandibular joint ankylosis:etiology and onset age显示文摘 | Kino K Ohmura Y | 1994 | J Jpn Soc TMJ1994,6,: | 1 |
| 9 | Thermophilic biodesulfurization of dibenzothiophene and its derivatives by Mycobacterium phlei WU-F1显示文摘 | Furuya T Kirimura K Kino K | 2001 | FEMS Microbiology Letters2001,204,10: | 1 |
| 10 | Effect of neurosphere size on the growth rate of human neural stem/progenitor cells显示文摘 | MORI H NINOMIYA K KINO OKA M | 2006 | J Neurosci Res2006,84,8: | 1 |
| 11 | Association analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high serum IgE phenotypes显示文摘 | Pykalainen M Kinos R Valkonen S | 2005 | Allergy Clin Immunol2005,115,1: | 1 |
| 12 | Human glucocorticoid receptor isoform p: recent understanding of its potential implications in physiology and pathophysiology显示文摘 | Kino T Su Y A Chrousos G P | 2009 | Cellular and Molecular Life Sciences2009,66,: | 1 |
| 13 | Tunable mechanically induced long-period fiber gratings显示文摘 | S. Savin M. Digonnet G.S. Kino H.J.Shaw | | 0,,10: | 1 |
| 14 | Interactions of the circadian CLOCK system and the HPA axis显示文摘 | Nader N Chrousos G P Kino T | 2010 | Trends Endocrinol Metab2010,21,5: | 1 |
| 15 | Roles of carbohydrates on Cry j 1,the major allergen of Japanese cedar pollen,in specific T-cell responses显示文摘 | Okano M Kino K Takishita T | 2001 | J Allergy Clin Immunol2001,108,: | 1 |
| 16 | Effects of pyrroloquinoline quinone (PQQ) and PQQ - oxazole on DNA synthesis of cultured human fibroblasts 显示文摘 | NAITO Y KUMAZAWA T KINO I | 1993 | Life Sci1993,52,24: | 1 |
| 17 | The human glucocorticoid receptor: molecular basis of biologic function 显示文摘 | Nieolaides N C Galata Z Kino T | 2010 | Steroids2010,75,1: | 1 |
| 18 | Tumor necrosis factor alpha receptor-and Fas-associated FLASH inhibit transcriptional activity of the glucocorticoid receptor by binding to and interfering with its interaction with p160 type nuclear receptor coactivators显示文摘 | Kino T Chrousos GP | 2003 | J Biol Chem2003,278,5: | 1 |
| 19 | Multiporous cellulose microcarrier for the development of a hybrid artificial liver using isolated hepatocytes显示文摘 | Kino Y Sawa M Kasai S | 1998 | J Surg Res1998,79,: | 1 |
| 20 | Role of apoptosis in modulation of the growth of human colorectal adenomas显示文摘 | Arai T Kino I | 1995 | J Pathol1995,173,: | 1 |