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| 1 | Genotyping-by-sequencing of pear (Pyrus spp.) accessions unravels novel patterns of genetic diversity and selection footprints显示文摘Understanding of genetic diversity and marker-trait relationships in pears(Pyrus spp.)forms an important part of gene conservation and cultivar breeding.Accessions of Asian and European pear species,and interspecific hybrids were planted in a common garden experiment.Genotyping-by-sequencing(GBS)was used to genotype 214 accessions,which were also phenotyped for fruit quality traits.A combination of selection scans and association analyses were used to identify signatures of selection.Patterns of genetic diversity,population structure and introgression were also investigated.About 15000 high-quality SNP markers were identified from the GBS data,of which 25%and 11%harboured private alleles for European and Asian species,respectively.Bayesian clustering analysis suggested negligible gene flow,resulting in highly significant population differentiation(Fst=0.45)between Asian and European pears.Interspecific hybrids displayed an average of 55%and 45%introgression from their Asian and European ancestors,respectively.Phenotypic(firmness,acidity,shape and so on)variation between accessions was significantly associated with genetic differentiation.Allele frequencies at large-effect SNP loci were significantly different between genetic groups,suggesting footprints of directional selection.Selection scan analyses identified over 20 outlier SNP loci with substantial statistical support,likely to be subject to directional selection or closely linked to loci under selection. | Satish Kumar Chris Kirk Cecilia Deng Claudia Wiedow Mareike Knaebel Lester Brewer | 2017 | Horticulture Research2017，4，1： | 8 |
| 2 | Systematic review and meta-analysis of technique for closure of the pancreatic rem- nant after distal pancreatectomy 显示文摘 | Knaebel HP Diener MK Wente MN | 2005 | Br J Surg2005，92，5： | 1 |
| 3 | Pressure Swing Adsorption:Development of an Equilibrium Theory for Gas Separation显示文摘 | KNAEBEL K S HILL F B | 1985 | Chem Eng Sci1985，40，12： | 1 |
| 4 | Integrated Steps in Pressure Swing Adsorption Cycles显示文摘 | KAYSER J C KNAEBEL K S | 1988 | Chem Eng Sci1988，43，： | 1 |
| 5 | Pressure Swing Adsorption:Development of an Equilibrium Theory for Binary Gas Mixtures with Nonlinear Isotherms显示文摘 | KAYSER J C KNAEBEL K S | 1989 | Chem Eng Sci1989，44，： | 1 |
| 6 | A systematic re- view and meta-analysis of pylorus-preserving versus classical pancreaticoduodenectomy for surgical treatment of periampulla- ry and pancreatic carcinoma显示文摘 | Diener MK Knaebel HP Heukaufer C | 2007 | Ann Surg2007，245，2： | 1 |
| 7 | Systematic review and recta-analysis of technique for closure of the pancreatic remnant after distal pancreatectomy显示文摘 | Knaebel HP Diener MK Wente MN | 2005 | Br J Surg2005，92，5： | 1 |
| 8 | A syslemalic review and melaanalysis of pylorus-preserving versus elassical pancreaticoduodenectomy for surgical treatment of periampullary and pancreatic carcinoma 显示文摘 | Diener MK Knaebel HP Heukaufer C | 2007 | Ann Surg2007，245，2： | 1 |
| 9 | Immune Response Against Frameshift-Induced Neopeptides in HNPCC Patients and Healthy HNPCC Mutation Carriers显示文摘 | Yvette Schwitalle Matthias Kloor Susanne Eiermann Michael Linnebacher Peter Kienle Hanns Peter Knaebel Mirjam Tariverdian Axel Benner Magnus von Knebel Doeberitz | 2008 | Gastroenterology2008，，4： | 1 |
| 10 | Effect of mineral and organic soil constituents on microbial mineralisation of organic compounds in anatural soil 显示文摘 | Knaebel D B Federle T W Mc Avoy D C | 1994 | Appl Environ Microbiol1994，60，12： | 1 |
| 11 | Pressure Swing Adsorption:A Theoretical Study of Oxygen and Nitrogen Gas Mixtures on 5A Molecular Sieve显示文摘 | SHIN H S KNAEBEL K S | 1987 | AIChE1987，33，4： | 1 |
| 12 | Vascular clips versus ligatures in thyroid surgery—results of a multicenter randomized controlled trial (CLIVIT Trial)显示文摘 | Markus K. Diener Christoph M. Seiler Moritz Frankenberg Kathleen Rendel Silke Schüle Katja Maschuw Stefan Riedl Jens C. Rückert Christian Eckmann Uwe Scharlau Alexis Ulrich Thomas Bruckner Hanns-Peter Knaebel Matthias Rothmund Markus W. Büchler | 2012 | Langenbeck’s Archives of Surgery2012，，7： | 1 |
| 13 | Simulation and optimization of a pressure swing adsorption system: Recovering hydrogen from methane显示文摘 | Knaebel S P Ko D Biegler L T | 2005 | Adsorption2005，11，： | 1 |
| 14 | Microsatellite instabilityin colorecta] cancer is associated with local lymphocyte infiltrationand low frequency of distant metastases显示文摘 | Buckowitz A Knaebel HP Benner A | 2005 | Br J Cancer2005，92，9： | 1 |
| 15 | Systematic review and meta-analysis of technique for closure, of the pancreatic remnant after distal panereatectomy 显示文摘 | Knaebel HP Diener MK Wente MN | 2005 | Br J Surg2005，92，5： | 1 |
| 16 | Early Antibiotic Treatment for Severe Acute Necrotizing Pancreatitis: A Randomized, Double-Blind, Placebo-Controlled Study显示文摘 | E Patchen Dellinger Jose M. Tellado Norberto E. Soto Stanley W. Ashley Philip S. Barie Thierry Dugernier Clement W. Imrie Colin D. Johnson Hanns-Peter Knaebel Pierre-Francois Laterre Enrique Maravi-Poma Jorge J. Olsina Kissler Miguel Sanchez-Garcia Stefan | 2007 | Annals of Surgery2007，，5： | 1 |
| 17 | Diffusing wave spectroscopy study of the motion of magnetic paticles in chemically cross-linked gels under External magnetic field显示文摘 | Tetsuharu Narita Alexandra Knaebel Jean Pierre Munch | 2003 | Macromolecules2003，36，： | 1 |
| 18 | Pressure Swing Adsorption: Development of an Equilibrium Theory for Binary Gas Mixtures with Nonlinear Isotherms 显示文摘 | KAYSER J C KNAEBEL K S | 1989 | Chem Eng Sci1989，44，： | 1 |
| 19 | Pressure Swing Adsorption: A Theoretical Study of Oxygen and Nitrogen Gas Mixtures on 5A Molecular Sieve 显示文摘 | SHIN H S KNAEBEL K S | 1987 | AICHE1987，33，4： | 1 |
| 20 | Sequential hepatic and pulmonary resections for metastatic colorectal cancer显示文摘 | Lehnert T Knaebel HP Duck M etal | 1999 | Br J Surg1999，86，2： | 1 |
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