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| 1 | SMALL ORGAN SIZE 1 and SMALL ORGAN SIZE 2/DWARF AND LOW-TILLERING Form aComplex to Integrate Auxin and Brassinosteroid Signaling in Rice显示文摘尽管植物生长素和 brassinosteroid (BR ) synergistically 控制各种各样的植物回答,位于 auxin-BR 串音下面的分子的机制很好没被理解。我们以前识别了 SMOS1,一个调整植物生长素的 APETALA2 类型抄写因素,作为小机关的原因的基因缩放 1 (smos1 ) 被各种各样的机关的一种减少的最后的尺寸在米饭描绘的异种。在这研究,我们识别了另一 smos 异种, smos2,哪个表演与 smos1 难区分的显型。SMOS2 与以前报导的矮子和 LOW-TILLERING (DLT ) 相同,它编码涉及 BR 发信号的 GRAS 蛋白质。SMOS1 和 SMOS2/DLT 身体上交往合作地在酵母并且在米饭原子核提高 transcriptional transactivation 活动。一致地, OsPHI-1 的表示, SMOS1 的一个直接目标,当 SMOS1 和 SMOS2/DLT 蛋白质两个都是在米饭房间的现在时,仅仅是 upregulated。一起拿,我们的结果建议 SMOS1 和 SMOS2/DLT 在在米饭表明串音的 auxin-BR 上形成重点建筑群。 | Ko Hirano Hideki Yoshida Koichiro Aya Mayuko Kawamura Makoto Hayashi Tokunori Hobo Karma Sato-lzawa Hidemi Kitano Miyako Ueguchi-Tanaka Makoto Matsuoka | 2017 | Molecular Plant2017,10,4: | 20 |
| 2 | Isolation of a Novel Lodging Resistance QTL Gene Involved in Strigolactone Signaling and Its Pyramiding with a QTL Gene Involved in Another Mechanism显示文摘住宿是到达到增加的庄稼生产率的一个主要障碍。在一次尝试到在米饭为灰煤杆力量理解机制,我们孤立一个有效量的特点地点( QTL ),强壮的 CULM3 ( SCM3 ),哪个与米饭 TEOSINTE BRANCHED1 ( OsTB1 )相同的原因的基因,基因以前报导了断然控制发信号的 strigolactone ( SL )。带 SCM3 的一根 near-isogenic 线(无) 证明尽管有期望的减少,提高的灰煤杆力量和增加的小穗状花小穗在 tiller 数字数,显示 SL 也有在提高灰煤杆力量和小穗状花小穗数字的一个积极角色。我们生产了带 SCM3 和 SCM2 的一根节节上升的线,编码涉及圆锥花序开发的 APO1 的另一 QTL。NIL-SCM2+SCM3 比 NIL-SCM2 和 NIL-SCM3 和这些 QTL 的添加剂效果引起的一个增加的小穗状花小穗数字显示出强壮得多的灰煤杆。我们讨论没有为繁殖导致有害特点,利用这些强壮的灰煤杆 QTL 的合适的等位基因的重要性。 | Kenji Yano Taiichiro Ookawa Koichiro Aya Yusuke Ochiai Tadashi Hirasawa Takeshi Ebitani Takeshi Takarada Masahiro Yano Toshio Yamamoto Shuichi Fukuoka Jianzhong Wu Tsuyu Ando Reynante Lacsamana Ordonio Ko Hirano Makoto Matsuoka | 2015 | Molecular Plant2015,8,2: | 12 |
| 3 | OsIDD2, a zinc finger and INDETERMINATE DOMAIN protein, regulates secondary cell wall formation显示文摘Previously, we found 123 transcription factors(TFs) as candidate regulators of secondary cell wall(SCW)formation in rice by using phylogenetic and co-expression network analyses. Among them, we examined in this work the role of OsIDD_2, a zinc finger and indeterminate domain(IDD) family TF. Its overexpressors showed dwarfism, fragile leaves, and decreased lignin content, which are typical phenotypes of plants defective in SCW formation, whereas its knockout plants showed slightly increased lignin content.The RNA-seq and quantitative reverse transcription polymerase chain reaction analyses confirmed that some lignin biosynthetic genes were downregulated in the OsIDD_2-overexpressing plants, and revealed the same case for other genes involved in cellulose synthesis and sucrose metabolism. The transient expression assay using rice protoplasts revealed that OsIDD_2 negatively regulates the transcription of genes involved in lignin biosynthesis, cinnamyl alcohol dehydrogenase 2 and 3(CAD_2 and 3), and sucrose metabolism, sucrose synthase 5(SUS_5), whereas an Alpha Screen assay, which can detect the interaction between TFs and their target DNA sequences, directly confirmed the interaction between OsIDD_2 and the target sequences located in the promoter regions of CAD_2 and CAD_3. Based on these observations, we conclude that OsIDD_2 is negatively involved in SCW formation and other biological events by downregulating its target genes. | Peng Huang Hideki Yoshida Kenji Yano Shunsuke Kinoshita Kyosuke Kawai Eriko Koketsu Masako Hattori Sayaka Takehara Ji Huang Ko Hirano Reynante Lacsamana Ordonio Makoto Matsuoka Miyako Ueguchi-Tanaka | 2018 | Journal of Integrative Plant Biology2018,60,2: | 3 |
| 4 | Clinical diagnostic criteria of IgG4-related sclerosing cholangitis 2012显示文摘 | Hirotaka Ohara Kazuichi Okazaki Hirohito Tsubouchi Kazuo Inui Shigeyuki Kawa Terumi Kamisawa Susumu Tazuma Kazushige Uchida Kenji Hirano Hitoshi Yoshida Takayoshi Nishino Shigeru Ko Nobumasa Mizuno Hideaki Hamano Atsushi Kanno Kenji Notohara Osamu Hasebe | 2012 | Journal of Hepato-Biliary-Pancreatic Sciences2012,,5: | 3 |
| 5 | Clinical diagnostic criteria of IgG4-related sclerosing cholangitis 2012显示文摘 | Hirotaka Ohara Kazuichi Okazaki Hirohito Tsubouchi Kazuo Inui Shigeyuki Kawa Terumi Kamisawa Susumu Tazuma Kazushige Uchida Kenji Hirano Hitoshi Yoshida Takayoshi Nishino Shigeru Ko Nobumasa Mizuno Hideaki Hamano Atsushi Kanno Kenji Notohara Osamu Hasebe | 2012 | Journal of Hepato-Biliary-Pancreatic Sciences2012,,5: | 1 |
| 6 | Characterization ofthe molecular mechanism underlying gibberellin perceptioncomplex formation in rice 显示文摘 | Ko Hirano Kenji A Hiroyuki T | 2010 | The Plant Cell2010,22,8: | 1 |
| 7 | Thesuppressive funcation of the rice DELLA protein SLR1 isdependent on its transcriptional activation activity 显示文摘 | Ko Hirano Eriko Kouketu Hiroe Katoh | 2012 | ThePlant Journal2012,71,: | 1 |
| 8 | Integrated genome-wide differentiation and association analyses identify causal genes underlying breeding-selected grain quality traits in japonica rice显示文摘Improving grain quality is a primary objective in contemporary rice breeding.Japanese modern rice breeding has developed two different types of rice,eating and sake-brewing rice,with different grain characteristics,indicating the selection of variant gene alleles during the breeding process.Given the critical importance of promptly and efficiently identifying genes selected in past breeding for future molecular breeding,we conducted genome scans for divergence,genome-wide association studies,and map-based cloning.Consequently,we successfully identified two genes,OsMnS and OsWOX9D,both contributing to rice grain traits.OsMnS encodes a mannan synthase that increases the white core frequency in the endosperm,a desirable trait for sake brewing but decreases the grain appearance quality.OsWOX9D encodes a grass-specific homeobox-containing transcription factor,which enhances grain width for better sake brewing.Furthermore,haplotype analysis revealed that their defective alleles were selected in East Asia,but not Europe,during modern improvement.In addition,our analyses indicate that a reduction in grain mannan content during African rice domestication may also be caused a defective OsMnS allele due to breeding selection.This study not only reveals the delicate balance between grain appearance quality and nutrition in rice but also provides a new strategy for isolating causal genes underlying complex traits,based on the concept of“breeding-assisted genomics”in plants. | Hideki Yoshida Satoshi Okada Fanmiao Wang Shohei Shiota Masaki Mori Mayuko Kawamura Xue Zhao Yiqiao Wang Naho Nishigaki Asako Kobayashi Kotaro Miura Shinya Yoshida Masaru Ikegami Akitoshi Ito Lin-Tzu Huang Yue-le Caroline Hsing Yoshiyuki Yamagata Yoichi Morinaka Masanori Yamasaki Toshihisa Kotake Eiji Yamamoto Jian Sun Ko Hirano Makoto Matsuoka | 2023 | Molecular Plant2023,16,9: | 0 |