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| 1 | Iron overload and cofactors with special reference to alcohol,hepatitis C virus infection and steatosis/insulin resistance显示文摘有几个余因子,影响身体铁新陈代谢并且加速铁超载。酒精和肝的病毒的感染是为在铁超载澄清余因子的角色的最典型的例子。处于这些条件,铁在房间和通过 Fenton 反应生产的反应的氧种类(ROS ) 有的 hepatocytes 和 Kupffer 被扔便于 transferrin 固定的铁的细胞的举起的关键角色。而且, hepcidin,主要在肝生产的抗菌剂肽为肠的铁吸收和网状内皮组织的铁版本也负责。在有血浆铜蓝蛋白缺乏的病人,在肝和 neurodegeneration 的贫血症和第二等的铁超载被报导。而且,正在积累没有酒精和肥胖的脂肪酸累积自己修改铁超载状态的证据。无效红血球生成也是一个重要因素加速铁超载,它与象地中海贫血和 myelodysplastic 症候群那样的疾病被联系。当这个条件坚持时,饮食的铁吸收由于骨髓红血球生成的增长被增加,织物铁超载愿望此后发生。在迟发性皮肤卟啉症,铁是在肝积累的在第二。 | Yutaka Kohgo Katsuya Ikuta Takaaki Ohtake Yoshihiro Torimoto Junji Kato | 2007 | World Journal of Gastroenterology2007，13，35： | 4 |
| 2 | Efficacy and adverse events of cold vs hot polypectomy: A meta-analysis显示文摘AIM: To compare previously reported randomized controlled studies(RCTs) of cold and hot polypectomy, we systematically reviewed and clarify the utility of cold polypectomy over hot with respect to efficacy and adverse events.METHODS: A meta-analysis was conducted to evaluate the predominance of cold and hot polypectomy for removing colon polyps. Published articles and abstracts from worldwide conferences were searched using the keywords 'cold polypectomy'. RCTs that compared either or both the effects or adverse events of cold polypectomy with those of hot polypectomy were collected. The patients' demographics, endoscopic procedures, No. of examined lesions, lesion size, macroscopic and histologic findings, rates of incomplete resection, bleeding amount, perforation, and length of procedure were extracted from each study. A forest plot analysis was used to verify the relative strength of the effects and adverse events of each procedure. A funnel plot was generated to assess the possibility of publication bias.RESULTS: Ultimately, six RCTs were selected. No significant differences were noted in the average lesion size(less than 10 mm) between the cold and hot polypectomy groups in each study. Further, the rates of complete resection and adverse events, including delayed bleeding, did not differ markedly between cold and hot polypectomy. The average procedural time in the cold polypectomy group was significantly shorter than in the hot polypectomy group.CONCLUSION: Cold polypectomy is a time-saving procedure for removing small polyps with markedly similar curability and safety to hot polypectomy. | Mikihiro Fujiya Hiroki Sato Nobuhiro Ueno Aki Sakatani Kazuyuki Tanaka Tatsuya Dokoshi Shugo Fujibayashi Yoshiki Nomura Shin Kashima Takuma Gotoh Junpei Sasajima Kentaro Moriichi Jiro Watari Yutaka Kohgo | 2016 | World Journal of Gastroenterology2016，22，23： | 3 |
| 3 | Efficacy and adverse events of EMR and submucosal dissection for the treatment of colon neoplasms: a meta-analysis of studies comparing EMR and endoscopic submucosal dissection显示文摘 | Mikihiro Fujiya Kazuyuki Tanaka Tatsuya Dokoshi Motoya Tominaga Nobuhiro Ueno Yuhei Inaba Takahiro Ito Kentaro Moriichi Yutaka Kohgo | 2014 | Gastrointestinal Endoscopy2014，，： | 2 |
| 4 | Up-regulation of ADRP in fatty liver in human and liver steatosis in mice fed with high fat diet显示文摘 | Wataru Motomura Mitsutaka Inoue Takaaki Ohtake Nubuhiko Takahashi Miho Nagamine Satoshi Tanno Yutaka Kohgo Toshikatsu Okumura | 2005 | Biochemical and Biophysical Research Communications2005，，4： | 1 |
| 5 | Circulating transferrin receptor in human serum 显示文摘 | Kohgo Y Nishisato T Kondo H | 1986 | Br J Haematol1986，64，2： | 1 |
| 6 | Regulation of iron metabolism in HepG2 cell:a possible role for cytokines in the hepatic deposition of iron显示文摘 | Kohgo Y Kondo H | 1993 | Hepatology1993，18，： | 1 |
| 7 | Effects of geometry of Hydroxyapatite as a cel Isubstratum in BMP-induced ectopic bone formation显示文摘 | Jin QM Takita H Kohgo T | 2000 | J Biomed Mater Res2000，51，： | 1 |
| 8 | Chemospecific manipulations of a rigid polysaccharide: syntheses of novel chitosan derivatives with excellent sol- ubility in common organic solvents by regioselective 显示文摘 | SHI-ICHIRO NISHIMURA OSANMU KOHGO | 1991 | Chemical Macromolecules1991，24，： | 1 |
| 9 | Theoretical aspects of constitutive modeling for unsaturated soils显示文摘 | Kohgo Y Nakano M Miyazaki T | | 0，，04： | 1 |
| 10 | Centrifuge model tests of a rockfill dam and simulation using consolidation analysis method显示文摘 | Kohgo Y Takahashi A Suzuki | 2010 | Soils and Foundations2010，50，2： | 1 |
| 11 | Interleukin-6 enhance hepatic transferring uptake and ferritin expression in rats显示文摘 | Kohgo Y Kato J | 1994 | Hepatology1994，19，： | 1 |
| 12 | EIAF,an ets-oncogene family transcription factor显示文摘 | Shindoh M Higashino F Kohgo T | | 0，，01： | 1 |
| 13 | Novel perspectives in probiotic treatment: the efficacy and unveiled mechanisms of the physiological functions 显示文摘 | FUJIYA M KOHGO Y | 2010 | Clin J Gastroentero12010，3，3： | 1 |
| 14 | Thickened inner hypoechoic layer of the gallbladder wall in the diagnosis of anomalous pancreaticobiliary ductal union with endosonography显示文摘 | Satoshi Tanno Takeshi Obara Hiroyuki Maguchi Yusuke Mizukami Ryushi Shudo Tsuneshi Fujii Kuniyuki Takahashi Noriyuki Nishino Satoshi Arisato Yusuke Saitoh Hitoshi Ura Yutaka Kohgo | 1997 | Gastrointestinal Endoscopy1997，，： | 1 |
| 15 | Circulating transferrin receptor in human serum显示文摘 | KOHGO Y NISHISATO T KONDO H | 1986 | Br J Haematol1986，64，： | 1 |
| 16 | Body iron metabolism and pathophysiology of iron overload显示文摘 | Yutaka Kohgo Katsuya Ikuta Takaaki Ohtake Yoshihiro Torimoto Junji Kato | 2008 | International Journal of Hematology2008，，1： | 1 |
| 17 | Regulation of iron metabolism in HepG2 Cell:a possible role for cytokines in the hepatic deposition of iron显示文摘 | Hirayama M Kohgo Y Kondo H | 1993 | Hepatology1993，18，： | 1 |
| 18 | Interleukin-6 enhance hepatic trans-ferring uptake expression in rats显示文摘 | Kohune M Kohgo Y Kato J | 1994 | Hepatology1994，19，： | 1 |
| 19 | Chemospecific manipulations of a rigid polysaccharide, syntheses of novel chitosan derivatives with excellent solubility in common organic solvents by regioselective chemical modifications显示文摘 | Nishimura S I Kohgo O Kurita K | 1991 | Macromolecules1991，24，： | 1 |
| 20 | Hypoxia inducible factor-1 independent pathways in tumor angiogenesis显示文摘 | Mizukami Y Kohgo Y Chung D C | 2007 | Clin Cancer Res2007，13，19： | 1 |
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