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24篇 您的检索式:作者名="Kol F"
    题名 作者 年代 出处 被引量
1西地那非能改善慢性肾功能衰竭大鼠的勃起功能显示文摘勃起功能障碍(ED)和慢性肾衰竭(CRF)之间的关系已在几个研究中被报道。本研究旨在探讨长期使用西地那非是否能增强CRF诱导大鼠的勃起能力。此外,我们评估了该治疗对某些分子的影响,这些分子被认为在勃起生理学及CRF相关的ED中起关键作用。研究分三组:(1)年龄配对的对照组,(2)CRF诱导的大鼠模型组,(3)CRF诱导大鼠给予西地那非慢性给药组((5 mg /kg口服6周[CRF诱导后6周开始治疗])。 3个月时,所有的动物进行海绵体神经刺激(CNS)来评估勃起功能。在所有大鼠组进行,阴茎组织晚期糖化终产物(AGE的) / 5-羟甲基-2-糠醛,丙二醛(MDA),cGMP(ELISA),诱导型一氧化氮合酶(iNOS)和神经元型NOS(nNOS的)(Western印迹)分析。CRF诱导大鼠与对照组相比,勃起功能有显著降低(P 〈0.05)。CRF诱导大鼠西地那非治疗组(第3组),海绵体内压(ICP)和曲线下面积的 增加量,大于CRF诱导大鼠组(第2组)。此外,西地那非治疗下调了AGE,MDA和iNOS的水平,同时保持了CRF诱导阴茎组织的nNOS和cGMP含量。西地那非治疗组AGE,MDA,iNOS的下降和nNOS,cGMP水平的增加,增加了ICP和海绵体神经刺激(CNS)的总ICP,使得CRF诱导大鼠阴茎勃起功能得到改善。本研究的结果表明慢性西地那非给药对CRF诱导大鼠的勃起功能有治疗效果。Nilgun Gurbuz Arif Kol Tumay Ipekci Erhan Ates Asli Baykal Mustafa F Usta 2015Asian Journal of Andrology2015,17,5:3
2Long-term investigation of nonsurgical treatment for thoracolumbar and lumbar burst fractures:an outcome analysis in sight of spinopelvic balance显示文摘Kol er H Acosta F Hempfing A 0,,08:1
3Angiotensin 2 increases mitogen activator messenger RMA in cultured rat aortic smooth muscle cells 显示文摘Van Leeuwen R T J Kol A Andreotti F 1994Circulation1994,90,:1
4Biochemical and biophysical aspects of collagen nanostructure in the extracellular matrix显示文摘Kolácná L Bakesová J Varga F 2007Physiol Res2007,56,:1
5Lignin as a filler for rubber mixes in footwear production显示文摘Ushmarin N F Kol'tsov N I 2000Polymer Recycling2000,5,4:1
6Lignin as a filler for rubber mixes in footwear production显示文摘Ushmarin N F Kol'tsov N I 2000Polymer Recycling2000,5,4:1
7Angiotensin II increases plasminogen activator inhibitor type 1 and tissue type plasminogen activator messenger RNA in cultured rat aortic smooth muscle cells 显示文摘Van Leeuwen'RTJ Kol A Andreotti F 1994Circulation1994,90,1:1
8Glycerol-treated nuclear suspensions: an efficient preservation method for flow cytometric analysis of plant samples 显示文摘Kol F Lu anov M Itel J 2012Chromosome Research2012,20,:1
9Angiotensin Ⅱ increarses plasminogen activator inhibitor type 1 and tissue-type plasminogen activator messenger RNA in cultured rat aortic smooth muscle cells显示文摘Leeuwen RTJ Kol A Andreotti F 1994Circulation1994,90,1:1
10Spectral luminescent properties and dynamics of intramolecular processes in 2,4,5-triarylimidazoles显示文摘Gostev F E Kol'tsova L S Petrukhin A N 2003Journal of Photochemistry and Photobiology A:Chemistry2003,156,13:1
11Ischemic tolerance of rat hearts in acute and chronic phases of experimental diabetes显示文摘Ravingerová T Neckár J Kolár F 2003Mol Cell Biochem2003,249,12:1
12N-acetylcysteine Treatment Prevents the Up-Regulation of MnSOD in Chronically Hypoxic Rat Hearts显示文摘Balková P Hlavácková M Milerová M Neckár J Kolár F Novák F Nováková O 2011Physiological Research2011,,:1
13Reproductive outcome of fresh or frozen-thawed embryo transfer is similar in high-risk patients for ovarian hyperstimulation syndrome using GnRH agonist for final oocyte maturation and intensive luteal support显示文摘Imbar T Kol S Lossos F 2012Hum Reprod2012,27,3:1
14Angiotensin Ⅱ increases plasminogen activator messenger RNA in cultured rat aortic smooth muscle cells显示文摘van Leeuwen RT Kol A Andreottl F 1994Circulation1994,90,:1
15Reproductive outcome of fresh or frozen-thawed embryo transfer is similar in high-risk patients for ovarian hyperstimulation syndrome using GnRH agonist for final oocyte maturation and intensive luteal support显示文摘Imbar T Kol S Lossos F 2012Hum Reprod2012,27,:1
16Angiotensin II increases plasminogen activitor inhibitor type 1 and tissue-plasminogen activitor messenger RNA in cultured rat aortic smooth muscle cells显示文摘Van Leeuwen RT Kol A Andreotti F 1994Circulation1994,90,:1
17Connective tissue growth factor gene expression alters tumor progression in esophageal cancer显示文摘Kol Iopang A Friess H Dimola F F 2002Word J Surg2002,26,:1
18Lignin as a filler for rubber mixes in footwear production显示文摘Ushmarin N F Kol'tsov N I 2000Polymer Recycling2000,5,4:1
19The effect of chronic hypoxia on the developing cardiopulmonary system显示文摘Ostádal B Kolár F Pelouch V 1989Biomed Biochim Acta1989,48,23:1
20Angiotensin 2 increases plasminogen activator inhibitor type1 and tissue-type plasminogen activator messenger RMA in cultured rat aortic smooth muscle cells 显示文摘Van Leeuwen RTJ Kol A Andreotti F 1994Circulation1994,90,:1
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