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41篇 您的检索式:作者名="Kolonin"
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1Adipose tissue-derived progenitor cells and cancer显示文摘Recruitment of stem cells and partially differentiated progenitor cells is a process which accompanies and facilitates the progression of cancer.One of the factors complicating the clinical course of cancer is obesity,a progressively widespread medical condition resulting from overgrowth of white adipose tissue(WAT),com-monly known as white fat.The mechanisms by which obesity in uences cancer risk and progression are not completely understood.Cells of WAT secret soluble molecules(adipokines) that could stimulate tumor growth,although there is no consensus on which cell populations and which adipokines are important.Recent reports suggest that WAT-derived mesenchymal stem(stromal) cells,termed adipose stem cells(ASC),may represent a cell population linking obesity and cancer.Studies in animal models demonstrate that adipokines secreted by ASC can promote tumor growth by assisting in formation of new blood vessels,a process necessary for expansion of tumor mass.Importantly,migration of ASC from WAT to tumors has been demonstrated,indicating that the tumor microenvironment in cancer may be modulated by ASC-derived trophic factors in a paracrine rather than in an endocrine manner.Here,we review possible positive and adverse implications of progenitor cell recruitment into the diseased sites with a particular emphasis on the role in cancer progression of progenitors that are expanded in obesity.Charles F Bellows Mikhail G Kolonin 2010World Journal of Stem Cells2010,2,5:2
2Reversal of obesity bytargeted ablation of adipose tissue显示文摘Kolonin M G Saha P K Chan L 2004Nat Med2004,10,6:1
3Display technologies:application for the discovery of drug and gene delivery agents显示文摘Anna Sergeeva Mikhail Kolonin Jeffrey Molldrem Renata Pasqualini Wadih Arap 0,,15:1
4Reversal of obesity by targeted ablation of adipose tissue显示文摘Kolonin MG Saha PK C han L 2004Nat Med2004,10,6:1
5Display technologies:application for the discovery of drug and gene delivery agents显示文摘Sergeeva A Kolonin M G Molldrem1 J J 2006Adv Drug Deliv Rev2006,58,15:1
6Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries显示文摘KOLONIN MG BOVER L SUN J 2006Cancer Res2006,66,:1
7Reversal of obesity by targeted ablation of adipose tissue 显示文摘Kolonin MG Saha PK Chan L 2004Nat Med2004,10,6:1
8Steps toward mapping the human vasculature by phage display显示文摘Arap W Kolonin M G Trepel M 2002Nat Med2002,8,2:1
9Steps toward mapping the human vasculature by phage display显示文摘 Kolonin MG Trepel M 2002Nat Med2002,8,2:1
10Proteolytic Isoforms of SPARC Induce Adipose Stromal Cell Mobilization in Obesity显示文摘Chieh Tseng Mikhail G. Kolonin 2016Stem Cells2016,,:1
11Steps toward mapping the human vasculature by phage display显示文摘ARAP W KOLONIN M G TREPEL M 2002Nature medicine2002,8,2:1
12Steps toward mapping the human vascuhure by phage display 显示文摘Arap W Kolonin MG Trepel M 2002Nat Med2002,8,2:1
13Display technologies:application for the discovery of drug and gene delivery agents显示文摘SERGEE V A KOLONIN M G JEFFREY J 0,,15:1
14Reversal of obesity by targeted ablation of adipose tissue 显示文摘Kolonin MG Saha PK Chan L 2004Nat Med2004,10,6:1
15Combinatorial stem cell mobilization显示文摘KOLONIN M G SIMMONS P J 2009Nat Biotechnol2009,27,3:1
16Steps toward mapping the human vasculature by phage display显示文摘Arap W Kolonin MG Trepel M 2002Nat Med2002,8,2:1
17Display technolo- gies:application for the discovery of drug and gene delivery ag- ents显示文摘Sergeeva A Kolonin M G MoUdrem J J 2006Adv Drug Deliv Rev2006,58,15:1
18Display tech- nolagies: application for the discovery of drug and gene delivery agents显示文摘Sergeeva A Kolonin M G Molldrem M J J 2006Adv Drug Del Rev2006,58,15:1
19Combinatorial stem cell mobilization显示文摘Kolonin M G Simmons P J 2009Nat Biotechnol2009,27,3:1
20Reversal ofobesity by targeted ablation of adipose tissue 显示文摘Kolonin M G Saha P K Chan L 2004NatMed2004,10,6:1
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