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| 1 | 伏格列波糖抑制神经系统疾病及老年患者的餐后低血压状态显示文摘The authors examined blood pressure, glucose, insulin, and neurotensin before and after intake of 75 g glucose with or without voglibose in 28 neurologic patients and 20 healthy controls. Voglibose significantly prevented hypotension and neurotensin increment after glucose intake and had no influence on glucose or insulin increment. These results suggest that voglibose benefits postprandial hypotension. | Maruta T. Komai K. Takamori M. Yamada M. 张嘉靖(译) | 2006 | 世界核心医学期刊文摘(神经病学分册)2006，2，9： | 3 |
| 2 | Antimutagens from gaiyou ( Artemisia argyi Levl, et vant ) 显示文摘 | Nakasugi T Nakashima M Komai K | 2000 | Journal of Agricultural and Food Chemistry2000，48，8： | 2 |
| 3 | Kidney GATA3^(+) regulatory T cells play roles in the convalescence stage after antibody-mediated renal injury显示文摘FoxP3^(+)regulatory T cells(Tregs)play crucial roles in peripheral immune tolerance.In addition,Tregs that reside or accumulate in nonlymphoid tissues,called tissue Tregs,exhibit tissue-specific functions and contribute to the maintenance of tissue homeostasis and repair.In an experimental mouse model of crescentic glomerulonephritis induced by an anti-glomerular basement membrane antibody,Tregs started to accumulate in the kidney on day 10 of disease onset and remained at high levels(~30–35%of CD4^(+)T cells)during the late stage(days 21–90),which correlated with stable disease control.Treg depletion on day 21 resulted in the relapse of renal dysfunction and an increase in Th1 cells,suggesting that Tregs are essential for disease control during the convalescence stage.The Tregs that accumulated in the kidney showed tissue Treg phenotypes,including high expression of GATA3,ST2(the IL33 receptor subunit),amphiregulin(Areg),and PPARγ.Although T-bet^(+) Tregs and RORγt^(+) Tregs were observed in the kidney,GATA3^(+) Tregs were predominant during the convalescence stage,and a PPARγagonist enhanced the accumulation of GATA3^(+) Tregs in the kidney.To understand the function of specific genes in kidney Tregs,we developed a novel T cell transfer system to T cell-deficient mice.This experiment demonstrates that ST2,Areg,and CCR4 in Tregs play important roles in the accumulation of GATA3^(+) Tregs in the kidney and in the amelioration of renal injury.Our data suggest that GATA3 is important for the recruitment of Tregs into the kidney,which is necessary for convalescence after renal tissue destruction. | Ryota Sakai Minako Ito Kyoko Komai Mana Iizuka-Koga Kazuhiko Matsuo Takashi Nakayama Osamu Yoshie Koichi Amano Hiroshi Nishimasu Osamu Nureki Masato Kubo Akihiko Yoshimura | 2021 | Cellular & Molecular Immunology2021，18，5： | 2 |
| 4 | Comparison of Ca^2+,Sr^2+,and Mn^2+ fluxes in mitochondria of the perfused rat heart显示文摘 | Hunter DR Komai H Haworth RA | 1980 | Circ Res1980，47，5： | 1 |
| 5 | Role of local hyperfibrinolysis in the etiology of chronic subdural hematoma显示文摘 | Ito H Yamamoto S Komai T | | 0，，01： | 1 |
| 6 | The soft budget constraint 显示文摘 | Komai J | 1986 | Kyklos1986，39，1： | 1 |
| 7 | Vascular endothelial growth faetor C and vascular endothelial growth factor rectptor 2 are relat- ed closely to the prognosis of Patients with ovarian carcinoma显示文摘 | Nishida N Yano H Komai K | 2004 | Cancer2004，101，6： | 1 |
| 8 | Plant growth inhibitor in the seeds of catchweed显示文摘 | Koichiro Komai | 1983 | Zasso Kenkyu1983，28，3： | 1 |
| 9 | Nematicidal activities of matrine and its derivatives against pine wood nematodes显示文摘 | MATSUDA K KIMURA M KOMAI K | 1991 | Joumal of Agricultural and Food Chemistry1991，39，1： | 1 |
| 10 | Antifeedants in Cyperaceae: coumaran and quinones from Cyperus spp.显示文摘 | Masanori Morimoto Yuko Fujii Koichiro Komai | 1999 | Phytochemistry1999，，5： | 1 |
| 11 | Plant growth inhibitory activities of iridoid glucosides显示文摘 | Komai Koichiro | 1990 | Zasso Kenkyu1990，35，1： | 1 |
| 12 | The Us3 protein kinase of herpes simplex virus 1 blocks apoptosis and induces phosporylation of the Bc1-2 family member Bad显示文摘 | Cartier A Komai T Masucci M G | | 0，，01： | 1 |
| 13 | Production of fertile somatic hybrid plants between Oriental hybrid lily and Lilium x formolongi显示文摘 | Horita M Morohashi H Komai F | 2003 | Planta2003，217，4： | 1 |
| 14 | Growth kinetics of CO2 hydrate just below melting point of ice 显示文摘 | Kawamura T Komai T Yamamoto Y | 2002 | Journal of Crystal Growth2002，234，： | 1 |
| 15 | Increased plasma levels of endothelin - 1 after cardiopulmonary bypass in patients with pulmonary hypertension and congenital heart disease 显示文摘 | Adatia T Elliott MJ | 1993 | J Thorac Cardiovasc Surg1993，106，： | 1 |
| 16 | Characterization of Fyn - mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N - methyl - D - aspartate receptor 显示文摘 | Nakazawa T Komai S Tezuka T | 2001 | J Biol Chem2001，276，1： | 1 |
| 17 | Tumor marker in ovarian cancer显示文摘 | Komai K Nishida T | 2002 | Gan To Kagakn Ryoho2002，56，5： | 1 |
| 18 | Resveratol modulates murine collagen-induced arthritis by inhibiting Thl7 and B-cell function显示文摘 | Xuzhu G Komai Korea M Leung BP | 2012 | Ann Rheum Dis2012，71，1： | 1 |
| 19 | Activation of NF- κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines 显示文摘 | Tsubaki M Komai M Fujimoto S | 2013 | J Exp Clin Cancer Res2013，32，： | 1 |
| 20 | Mitogenic activity of oxidized lipoprotein(a)on human vascular smooth muscle cells 显示文摘 | Komai N Morishita R Yamada S | 2002 | Hypertension2002，40，： | 1 |
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