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| 1 | Histopathological comparison of topical therapy modalities for acute radiation proctitis in an experimental rat model显示文摘瞄准:与福尔马林相比评估为尖锐放射直肠炎的治疗可得到的流行热门治疗学的形式。方法:120 只老鼠的一个总数被使用。四个组(n = 30 ) 为每下列应用治疗形式与一个组一起被分析:控制, mesalazine,福尔马林, betamethasone,和 misoprostol。17.5 Gy 的单个部分被送到每只老鼠。在组老鼠被给 saline 的控制的老鼠,和在另外的三个组的老鼠在照耀以后开始第一天直到无痛苦的死亡的日子的一天收到了适当灌肠剂两次。在 d 上 5, 10,和 15,从每个组的十只老鼠是 euthanized,不知道处理赋值的一个病理学家用一个得分系统检验了直肠。结果:为表面上皮,腺(地窟) 和直肠的薄板 propria 基质的组织病理学说的分数在 d 上到达了他们的最大的水平 10。控制和福尔马林组有最高并且有的 mesalazine 最低,分别地在 d 上 10。在第 15 d 上, mesalazine, betamethasone,和 misoprostol 有 betamethasone 的最低分数。结论:Mesalazine, betamethasone,和 misoprostol 是最好的热门代理人因为放射直肠炎和福尔马林有煽动性的效果并且不应该被使用。 | Cagatay Korkut Oktar Asoglu Murat Aksoy Yersu Kapran Hatice Bilge Nese Kiremit-Korkut Mesut Parlak | 2006 | World Journal of Gastroenterology2006，12，30： | 18 |
| 2 | Intussusception in adults:Clinical characteristics,diagnosis and operative strategies显示文摘AIM:To evaluate 20 adults with intussusception and to clarify the cause, clinical features, diagnosis, and management of this uncommon entity.METHODS: A retrospective review of patients aged >18 years with a diagnosis of intestinal intussusception between 2000 and 2008. Patients with rectal prolapse, prolapse of or around an ostomy and gastroenterostomy intussusception were excluded. RESULTS: There were 20 cases of adult intussusception. Mean age was 47.7 years. Abdominal pain, nausea, and vomiting were the most common symptoms. The majority of intussusceptions were in the small intestine (85%). There were three (15%) cases of colonic intussusception. Enteric intussusception consisted of five jejunojejunal cases, nine ileoileal, and four cases of ileocecal invagination. Among enteric intussusceptions, 14 were secondary to a benign process, and in one of these, the malignant cause was secondary to metastatic lung adenocarcinoma. All colonic lesions were malignant. All cases were treated surgically. CONCLUSION: Adult intussusception is an unusual and challenging condition and is a preoperative diagnostic problem. Treatment usually requires resection of the involved bowel segment. Reduction can be attempted in small-bowel intussusception if the segment involved is viable or malignancy is not suspected; however, a more careful approach is recommended in colonic intussusception because of a significantly higher coexistence of malignancy. | Savas Yakan Cemil Caliskan Ozer Makay Ali Galip Denecli Mustafa Ali Korkut | 2009 | World Journal of Gastroenterology2009，15，16： | 12 |
| 3 | Post-hepatectomy liver regeneration in the context of bile acid homeostasis and the gut-liver signaling axis显示文摘Background:Liver regeneration following partial hepatectomy(PHx)is a complicated process involving multiple organs and several types of signaling networks.The bile acid-activated metabolic pathways occupy an auxiliary yet important chapter in the entire biochemical story.PHx is characterized by rapid but transient bile acid overload in the liver,which constitutes the first wave of proliferative signaling in the remnant hepatocytes.Bile acids trigger hepatocyte proliferation through activation of several nuclear receptors.Following biliary passage into the intestines,enterocytes reabsorb the bile acids,which results in the activation of farnesoid X receptor(FXR),the consequent excretion of fibroblast growth factor(FGF)19/FGF15,and its release into the enterohepatic circulation.FGF19/FGF15 subsequently binds to its cognate receptor,fibroblast growth factor receptor 4(FGFR4)complexed withβ-klotho,on the hepatocyte membrane,which initiates the second wave of proliferative signaling.Because some bile acids are toxic,the remnant hepatocytes must resolve the potentially detrimental state of bile acid excess.Therefore,the hepatocytes orchestrate a bile acid detoxification and elimination response as a protective mechanism in concurrence with the proliferative signaling.The response in part results in the excretion of(biotransformed)bile acids into the canalicular system,causing the bile acids to end up in the intestines.Relevance for patients:Recently,FXR agonists have been shown to promote regeneration via the gut-liver axis.This type of pharmacological intervention may prove beneficial for patients with hepatobiliary tumors undergoing PHx.In light of these developments,the review provides an in-depth account of the pathways that underlie post-PHx liver regeneration in the context of bile acid homeostasis in the liver and the gut-liver signaling axis. | Lianne de Haan Sarah Jvan der Lely Anne-Loes K.Warps Quincy Hofsink Pim B.Olthof Mark J.de Keijzer Daniel A.Lionarons Lionel Mendes-Dias Bote G.Bruinsma Korkut Uygun Hartmut Jaeschke Geoffrey C.Farrell Narci Teoh Rowan Fvan Golen Tiangang Li Michal Heger | 2018 | Journal of Clinical & Translational Research2018，4，1： | 2 |
| 4 | A new technique for abdominal heart transplantation in rats显示文摘 | Demirsoy E Arbatli H Korkut AK | 2003 | J Cardiovasc Surg2003，44，6： | 1 |
| 5 | Modeling of adsorption and ultrasonic desorption of cadmium(Ⅱ) and zinc(Ⅱ) on local bentonite显示文摘 | LACIN O BAYRAK B KORKUT O | 2005 | Journal of Colloid and Interface Science2005，292，2： | 1 |
| 6 | The compari- son of dexmedetomidine and midazolam used for sedation of patients during upper endoscopy: A prospective, randomized study 显示文摘 | DEMIRARAN Y KORKUT E TAMER A | 2007 | Can J Gastroenterol2007，21，1： | 1 |
| 7 | The effect of heat treatment on some chemical properties and colour in Scots pine and Uludag fir wood显示文摘 | Mehmet Akgul S Oleyman Korkut | 2012 | International Journal of Physical Sciences2012，7，21： | 1 |
| 8 | The Effect of Niobium on the Microst Ructure of Ferritic Stainless Steel 显示文摘 | Kuzucu V Aksoy M Korkut M H | 1997 | Mater Sci Eng1997，230，122： | 1 |
| 9 | Effect of particulate reinforcement on wear behavior of aluminium matrix composites显示文摘 | KORKUT M H | 2004 | Materials Science and Technology2004，20，： | 1 |
| 10 | Two successive pregnancies after ursodeoxycholic acid therapy in a previously infertile woman with antimitochondriM antibody-negative primary biliary cirrhosis显示文摘 | Korkut E Kisacik B Akcan Y | 2005 | Fertil Steril2005，83，： | 1 |
| 11 | A case study for the effect of a flow improvement device (a Partial wake equalizing duet)on ship Powering characteristics显示文摘 | KORKUTE | | 0，，02： | 1 |
| 12 | The effect ofniobium and homogenization on the wear resistance and somemechanical properties of ferritic stainless steel containingl7 - 18wt% chromium显示文摘 | Aksoy M Kuzucu V Korkut M H | 1999 | Journal of Materials Processing Technology1999，91，： | 1 |
| 13 | Strategies to rescue steatotic livers before transplantation in clinical and experimental studies显示文摘The shortage of donor livers has led to an increased use of organs from expanded criteria donors. Included are livers with steatosis, a metabolic abnormality that increases the likelihood of graft complications posttransplantation. After a brief introduction on the etiology, pathophysiology, categories and experimental models of hepatic steatosis, we herein review the methods to rescue steatotic donor livers before transplantation applied in clinical and experimental studies. The methods span the spectrum of encouraging donor weight loss, employing drug therapy, heat shock preconditioning, ischemia preconditioning and selective anesthesia on donors, and the treatment on isolated grafts during preservation. These methods work at different stages of transplantation process, although share similar molecular mechanisms including lipid metabolism stimulation through enzymes or nuclear receptor e.g. , peroxisomal proliferator-activated receptor, or anti-inflammation through suppressing cytokines e.g. , tumor necrosis factor-α, or antioxidant therapies to alleviate oxidative stress. This similarity of molecular mechanisms implies possible future attempts to reinforce each approach by repeating the same treatment approach at several stages of procurement and preservation, as well as utilizing these alternative approaches in tandem. | Qiang Liu Maria-Louisa Izamis Hongzhi Xu Tim Berendsen Martin Yarmush Korkut Uygun | 2013 | World Journal of Gastroenterology2013，19，29： | 1 |
| 14 | Effect of various fire retardants on surface roughness of plywood显示文摘 | Nadir Ayrilmis Suleyman Korkut Ercan Tanritanir | 2006 | Building and Environment2006，41，7： | 1 |
| 15 | The Effect of Niobium and Homogenization on the Wear Resistance and Some Mechanical Properties of Ferritie Stainless Steel Containing 17 218wt% Chromium 显示文摘 | Aksoy M Kuzucu V Korkut M H | 1999 | J Mater Process Technol1999，91，123： | 1 |
| 16 | Modeling of ad- sorption and ultrasonic desorption of cadmium( Ⅱ ) and zinc( Ⅱ ) on local bentonite显示文摘 | Oral Lacin Bahar Bayrak Ozlem Korkut | 2005 | Journal of Colloid and Interface Science2005，292，2： | 1 |
| 17 | The comparison of dexmedetomidine and midazolam used for sedation of patients during upper endoscopy:A prospective,randomized study显示文摘 | Demiraran Y Korkut E Tamer A | | 0，，01： | 1 |
| 18 | Investigation of the effect of rake angle on main cutting forces 显示文摘 | Gunay M Aslan E Korkut I | 2004 | International Journal of Machine Tools and Manufacture2004，44，9： | 1 |
| 19 | Development and operation of gold and cobalt oxide nanoparticles containing polypropylene based enzymatic fuel cell for renewable fuels显示文摘 | Kilic M S Korkut S Hazer B et aI | 2014 | Biosensors and Bioelectronics2014，61，： | 1 |
| 20 | Effect of various fire retardants on surface roughness of plywood 显示文摘 | Nadir Ayrilmis Suleyman Korkut Ercan Tanritanir | 2006 | Building and Environment2006，41，7： | 1 |
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