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| 1 | Prevalence of obesity and diabetes in patients with schizophrenia显示文摘AIM To compare the prevalence of diabetes in patients with schizophrenia treated at a community mental health center with controls in the same metropolitan area and to examine the effect of antipsychotic exposure on diabetes prevalence in schizophrenia patients. METHODS The study was a comprehensive chart review of psychiatric notes of patients with schizophrenia and schizoaffective disorder treated at a psychosis program in a community mental health center. Data collected included psychiatric diagnoses, diabetes mellitus diagnosis, medications, allergies, primary care status, height, weight, body mass index(BMI), substance use and mental status exam. Local population data was downloaded from the Centers for Disease Control Behavioral Risk Factor Surveillance System. Statistical methods used were χ~2 test, Student's t test, general linear model procedure and binary logistic regression analysis.RESULTS The study sample included 326 patients with schizophrenia and 1899 subjects in the population control group. Demographic data showed control group was on average 7.6 years older(P = 0.000), more Caucasians(78.7% vs 38.3%, P = 0.000), and lower percentage of males(40.7% vs 58.3%, P = 0.000). Patients with schizophrenia had a higher average BMI than the subjects in the population control(32.11, SD = 7.72 vs 27.62, SD = 5.93, P = 0.000).Patients with schizophrenia had a significantly higher percentage of obesity(58.5% vs 27%, P = 0.000) than the population group. The patients with schizophrenia also had a much higher rate of diabetes compared to population control(23.9% vs 12.2%, P = 0.000). After controlling for age sex, and race, having schizophrenia was still associated with increased risk for both obesity(OR = 3.25, P = 0.000) and diabetes(OR = 2.42, P = 0.000). The increased risk for diabetes remained even after controlling for obesity(OR = 1.82, P = 0.001). There was no difference in the distribution of antipsychotic dosage, second generation antipsychotic use or multiple antipsychotic use within different BMI categories or with diabetes status in the schizophrenia group. CONCLUSION This study demonstrates the high prevalence of obesity and diabetes in schizophrenia patients and indicates that antipsychotics may not be the only contributor to this risk. | Aniyizhai Annamalai Urska Kosir Cenk Tek | 2017 | World Journal of Diabetes2017，8，8： | 6 |
| 2 | Surgical outcomes after breast cancer surgery:measuring actute lymphedema显示文摘 | Rymal C Koppolu P | 2001 | J Surg Res2001，95，2： | 1 |
| 3 | Surgical outcomes after breast cancer surgery:Measuring actute lymph edema 显示文摘 | KOSIR M A RYMAL C KOPPOLU P | 2001 | J Surg Res2001，95，2： | 1 |
| 4 | Surgical outeomes after breast cancer surgery : Measuring actute lymph edema 显示文摘 | Kosir MA Rymai C Kppolu P | 2001 | J Surg Res2001，95，2： | 1 |
| 5 | Reversed phase monolithic analytical columns for the determination of HA1 subunit of influ-enza virus haemagglutinin显示文摘 | Urbas L Kosir B Peterka M | | 0，，17： | 1 |
| 6 | Pediatric abdominal lymphangiomas: a plea for early recognition显示文摘 | Kosir MA Sonnino RE Gauderer MWL | 1991 | J Pediatr Surg1991，26，1： | 1 |
| 7 | Alternative to the conven- tionalheating and cooling systems in public buildings 显示文摘 | Kosir M Krainer A Dovjak M | 2010 | StrojniSkivestnik-J Mech Eng2010，，56： | 1 |
| 8 | Determination of authenticy, regional origin, and vintage of Slovenian wines using a combination of IRMS and SNIF-NMR analyses显示文摘 | Ogrinc N Kosir I J Kocjancic M | 2001 | Journal of Agricultural and Food Chemistry2001，49，3： | 1 |
| 9 | Optimization of Multi-attribute User Modeling Approach显示文摘 | Matevz Pogacnik Jurij Tasic and Andrej Kosir | 2004 | International Journal of Electronics and Communications2004，，： | 1 |
| 10 | Is the ABO incompatibility a risk factor in bone marrow transplantation?显示文摘 | Rozman P Kosir A Bohinjec M | 2005 | Transpl Immu- nol2005，14，34： | 1 |
| 11 | Surgical outcomesafter breast cancer surgery: measuring actute lymph edema 显示文摘 | Kosir M A Rymal C Koppolu P | 2001 | J Surg Res2001，95，2： | 1 |
| 12 | Determination of reference genes for circadian studies in different tissues and mouse strains 显示文摘 | Kosir R Acimovic J Golicnik M | 2010 | BMC Mol Biol2010，11，： | 1 |
| 13 | Automaticauy controued daylighting for visual and non--visual effect 显示文摘 | Kosir M Krainer A Dovjak M | 2011 | Lighting Research and Technology2011，43，： | 1 |
| 14 | Surgical out comes after breast cancer surgery: measuring actute lymph edema显示文摘 | Kosir MA Rymai C Kppolu P | 2001 | J Surg Res2001，95，2： | 1 |
| 15 | Surgical cutcomes after breast cancer surgery: measuring acute lymph edema显示文摘 | Kosir MA Rymal C Koppolu P | 2001 | J Surg Res2001，95，： | 1 |
| 16 | CXCL7-mediated stimula- tion of lymphangiogenic factors VEGF-C, VEGF-D in human breast cancer cell显示文摘 | Yu M Berk R Kosir M A | 2010 | J Oncol2010，7，： | 1 |
| 17 | Acute lower extremity compartment syndrome (ALECS) screening protocol in critically ill trauma patients 显示文摘 | Kosir R Moore FA Selby JH | 2007 | J Trauma2007，63，2： | 1 |
| 18 | Identification of anthocyanins in wines by liquid chromatography, liquid chromatography-mass spectrometry and nuclear magnetic resonance显示文摘 | Kosir IJ Lapornik B Andrensek S | 2004 | Analytica Chimica Acta2004，513，： | 1 |
| 19 | Surgical outcomes after breast cancer surgery: Measuring actute lymph edema 显示文摘 | Kosir MA Rymai C Kppolu P | 2001 | J Surg Res2001，95，2： | 1 |
| 20 | Fuzzy control system for thermal and visual comfort in building显示文摘 | KRISTL Z KOSIR M MATEJA T L | 2008 | Renewble Energy2008，33，4： | 1 |
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