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| 1 | Postoperative adjunctive bevacizumab versus placebo in primary trabeculectomy surgery for glaucoma显示文摘AIM: To compare the effectiveness of postoperative adjunctive use of subconjunctival bevacizumab in altering the outcome of primary trabeculectomy in terms of sustained lowering of intraocular pressure(IOP) and reduction of postoperative bleb vascularization and fibrosis.METHODS: A prospective, one center, randomized, placebo-control study. Fifty-nine patients(59 eyes) with uncontrolled IOP under maximal tolerated medical treatment(MTMT) were recruited. A primary trabeculectomy with mitomycin C(MMC) was done and the patients were randomized to either postoperative subconjunctival injection of bevacizumab(1.25 mg/0.05 mL) or balanced salt solution(BSS). Forty-seven patients(47 eyes) completed at least one year of follow up and were included in the study. The main outcome measure was the IOP, and secondary outcome measures include bleb morphology, vascularization, and fibrosis, as well as the need for glaucoma medications and 5-fluorouracil(5-FU) needling.RESULTS: At 1-year follow up, there was no significant difference between groups for IOP(P=0.65), bleb morphology(P=0.65), and the need for glaucoma medications(P=0.65) or 5-FU needling requirements(P=0.11). However, the bevacizumab group had a higher rate of success results, lower use of glaucoma medications after surgery, and optimal bleb aspect in more patients, but more 5-FU needling procedures required. CONCLUSION: A bigger sample size is needed in order to determine whether the differences found in the bevacizumab group are statistically significant. | Sana’Muhsen Javiera Compan Tze Lai Christoph Kranemann Catherine Birt | 2019 | International Journal of Ophthalmology(English edition)2019，12，10： | 4 |
| 2 | Surgical repositioning of dislocated capsular tension rings 显示文摘 | AHMED I I CHEN S H KRANEMANN C | 2005 | Ophthalmology2005，112，110： | 1 |
| 3 | Small-incision iris fixation of foldable intraocular lenses in the absence of capsule support 显示文摘 | C-ondon GP Masket S i Kranemann C Crandall AS Ahmed Ⅱ | 2007 | Ophthalmology2007，114，7： | 1 |
| 4 | Surgical repositioning of dislocated capsular tension rings显示文摘 | Ahmed IIK Chen SH Kranemann C | 2005 | Ophthahmology2005，112，： | 1 |
| 5 | Optimal timing of capsular tension ring implantation:Miyake-Apple video analysis显示文摘 | Ahmed IIK Cionni RJ Kranemann C | 2005 | J Cataract Refract Surg2005，31，： | 1 |
| 6 | Ultrasound biomicroscopyin Sturge-Weber-associated glaucoma 显示文摘 | Kranemann CF Pavlin CJ Trope GE | 1998 | Am J Ophthalmol1998，125，： | 1 |
| 7 | Optimal timing of capsular tension ring implantation:miyake-apple video analysis显示文摘 | Ahmed IIK Cionni RJ Kranemann C | 2005 | J Cataract Refract Surg2005，31，9： | 1 |
| 8 | Surgical repositioning of dislocated capsular tension rign 显示文摘 | Ahmed II Chen SH Kranemann C | 2005 | Ophthalmology2005，112，17： | 1 |
| 9 | Surgical repositioning of dislocated capsular tension rings 显示文摘 | Ahmed I Chen S Kranemann C Wong D | 2005 | Ophthalmology2005，112，10： | 1 |
| 10 | Surgical repositioning of dislocated capsular tension rings, 显示文摘 | Ahmed II Chen SH Kranemann C | 2005 | Ophthalmology2005，112，10： | 1 |
| 11 | Revisiting early postoperative follow up after phaco-emulsification显示文摘 | Ahmed IIK Kranemann C Chipman M | 2002 | J Cataract Refract Surg2002，28，1： | 1 |
| 12 | Five-year results of 5-fluorouracil augmented needling revision of failing blebs显示文摘 | DALVI R ORZECH N KRANEMANN C | 2012 | Ophthalmic Surg Lasers Imaging2012，43，1： | 1 |
| 13 | Small-incision iris fi xation of foldable intraocular lenses in the absence of capsule support 显示文摘 | Condon GP Masket S Kranemann C | 2007 | Ophthalmol2007，114，7： | 1 |
| 14 | Small-incision iris fi xation of foldable intraocular lenses in the absence of capsule support显示文摘 | Condon GP Masket S Kranemann C | | 0，，07： | 1 |
| 15 | Optimal timing of cap- sular tension ring implantation: Miyake-Apple video analysis 显示文摘 | Ahmed II Cionni R J Kranemann C | 2005 | J Cataract Refract Surg2005，31，9： | 1 |
| 16 | Ultrasound biomicroscopy in Sturge-Weber-associated glaucoma 显示文摘 | Kranemann CF Pavlin CJ Trope GE | 1998 | Am Ophthalmol1998，125，1： | 1 |
| 17 | Ultrasound biomicroscopy in sturge-Weber-associated glaucoma显示文摘 | Kranemann CF Pavlin CJ Trope GE | 1998 | Am J Ophthamol1998，125，1： | 1 |
| 18 | Optimal timing of capsular tension ring implantation:Miyake-apple video analysis显示文摘 | Ahmed II Cionni RJ Kranemann C | 2005 | J Cataract Refract Surg2005，31，9： | 1 |
| 19 | Surgical repositioning of dislocated capsular tension rings显示文摘 | Ahmed Ⅱ Chen SH Kranemann C Wong DT | 2005 | Ophthalmology2005，112，10： | 1 |
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