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199篇 您的检索式：作者名="Kremmer"

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	题名	作者	年代	出处	被引量
1	The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy显示文摘The chemokine receptor CCR7 and its ligands CCL19 and CCL21 guide the homing and positioning of dendritic and T cells in lymphoid organs,thereby contributing to several aspects of adaptive immunity and immune tolerance.In the present study,we investigated the role of CCR7 in the pathogenesis of collagen-induced arthritis(CIA).By using a novel anti-human CCR7 antibody and humanized CCR7 mice,we evaluated CCR7 as a target in this autoimmune model of rheumatoid arthritis(RA).Ccr7-deficient mice were completely resistant to CIA and presented severely impaired antibody responses to collagen II(CII).Selective CCR7 expression on dendritic cells restored arthritis severity and anti-CII antibody titers.Prophylactic and therapeutic treatment of humanized CCR7 mice with anti-human CCR7 mAb 8H3-16A12 led to complete resistance to CIA and halted CIA progression,respectively.Our data demonstrate that CCR7 signaling is essential for the induction of CIA and identify CCR7 as a potential therapeutic target in RA.	Georgios L.Moschovakis Anja Bubke Michaela Friedrichsen Jasmin Ristenpart Jaap Willem Back Christine S.Falk Elisabeth Kremmer Reinhold Forster	2019	Cellular & Molecular Immunology2019，16，10：	3
2	Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death显示文摘	Alexander Seiler Manuela Schneider Heidi F?rster Stephan Roth Eva K. Wirth Carsten Culmsee Nikolaus Plesnila Elisabeth Kremmer Olof R?dmark Wolfgang Wurst Georg W. Bornkamm Ulrich Schweizer Marcus Conrad	2008	Cell Metabolism2008，，3：	2
3	l Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human esophagus 显示文摘	Gerber JK RichterT KremmerE et a	2002	J Patho2002，197，3：	1
4	显示文摘	Kremmer S Selbach J M Ayertey H D	2001	Klin Monbl Augenheilkd2001，218，4：	1
5	Novel mutation - specific monoclonal E - cadherin antibodies make possible allele differentiation at the protein level in tumors 显示文摘	Becker I Becker KF Kremmer E	1999	Verh Dtsch Ges Pathol1999，83，：	1
6	Role for erbin in bacterial activation of Nod2显示文摘	Kufer TA Kremmer E Banks DJ	2006	Infect Immun2006，74，6：	1
7	Analysis of E - cadherin in diffuse - type gastric cancer using a mutation - specific monoclonal antibody显示文摘	Becker KF Kremmer	1999	Am J Pathol1999，155，：	1
8	Protective effects of type Ⅰ and type Ⅱ interferon stoward Rous sarcoma virus-induced tumors in chickens显示文摘	PLACHY J WEINING K C KREMMER g	1999	Virology1999，256，1：	1
9	Protective effects of type I and type Ⅱ interferons toward Rous sarcoma virusinduced tumors in chickens显示文摘	Plachy J Weining K C Kremmer E	1999	Virology1999，256，1：	1
10	Dipeptide repeat protein pathology in C9orf72 mutation cases: clinico-pathological correlations 显示文摘	MACKENZIE I R ARZBERGER T KREMMER E	2013	Acta Neuropathologica2013，126，6：	1
11	Expression of deoxyurine triphosphatase (dUTPase) in colorectal tumors显示文摘	FLEISCHMANN J KREMMER E MULLER S	1999	Int J Cancer1999，84，：	1
12	Epstein-Barr virus encoded latent membrane protein 1 (LMP1) and TNF receptor associated factors (TRAF):colocalisation of LMP1 and TRAF1 in primary EBV infection and in EBV associated Hodgkin lymphoma显示文摘	Siegler G Kremmer E Gonnella R		0，，03：	1
13	Multi-parameter determination of TNFalpha, PCT and CRP for point-of-care testing显示文摘	Kramer P M Kess M Kremmer E	2011	Analyst2011，136，4：	1
14	Epstein-Barr virus encoded latent membrane protein 1 (LMP1)and TNF receptor associated factors(TRAF):colocalisation of LMP1 and TRAF1 in primary EBV infection and in EBV associated Hodgkin lymphorna显示文摘	Siegler G Kremmer E Gonnella R	2003	Mol Pathol2003，56，3：	1
15	A method for representing boundaries in discrete element modelling-part II-Kine- matics显示文摘	KREMMER M FAVIER J F	2001	International Journal for Numerical Methods in Engineering2001，51，：	1
16	The E-cadhefin repressor snail plays a role in tumor progression of endometrioid adenocarcinomas 显示文摘	Blechschmidt K Kremmer E Hollweck R Mylonas I Hofler H Kremer M	2007	Diagn Mol Pathol2007，16，4：	1
17	Helicobacter pylori induces MAPK phosphorylation and AP-1 activation via a NOD1- dependent mechanism 显示文摘	Allison CC Kufer TA Kremmer E	2009	J Immunol2009，183，12：	1
18	Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesoagus显示文摘	Gerber JK Richter T Kremmer E	2002	J Pathol2002，197，3：	1
19	Protective effects of type Ⅰ and type Ⅱ interferons toward Rous sarcoma virus-induced tumors in chickens显示文摘	Plachy J Weining K C Kremmer E	1999	Virology1999，256，1：	1
20	A method for representing boundaries in discrete element modelling - Part Ⅱ: Kinematics显示文摘	Kremmer M Favier J F	2001	International Journal for Numerical Methods in Engineering2001，51，：	1

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