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| 1 | Neuroimaging the brain-gut axis in patients with irritable bowel syndrome显示文摘AIM:To summarize and synthesize current literature on neuroimaging the brain-gut axis in patients with irritable bowel syndrome(IBS).METHODS:A database search for relevant literature was conducted using Pub Med,Scopus and Embase in February 2015.Date filters were applied from the year2009 and onward,and studies were limited to those written in the English language and those performed upon human subjects.The initial search yielded 797articles,out of which 38 were pulled for full text review and 27 were included for study analysis.Investigations were reviewed to determine study design,methodology and results,and data points were placed in tabular format to facilitate analysis of study findings across disparate investigations.RESULTS:Analysis of study data resulted in the abstraction of four key themes:Neurohormonal differences,anatomic measurements of brain structure and connectivity,differences in functional responsiveness of the brain during rectal distention,and confounding/correlating patient factors.Studies in this review noted alterations of glutamate in the left hippocampus(HIPP),commonalities across IBS subjects in terms of brain oscillation patterns,cortical thickness/gray matter volume differences,and neuroanatomical regions withincreased activation in patients with IBS:Anterio cingulate cortex,mid cingulate cortex,amygdala anterior insula,posterior insula and prefrontal cortex.A striking finding among interventions was the substantia influence that patient variables(e.g.,sex,psychologica and disease related factors)had upon the identification of neuroanatomical differences in structure and con nectivity.CONCLUSION:The field of neuroimaging can provide insight into underlying physiological differences that distinguish patients with IBS from a healthy population. | Kristen R Weaver Lee Anne B Sherwin Brian Walitt Gail D'Eramo Melkus Wendy A Henderson | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，2： | 8 |
| 2 | Recent advances in the molecular genetics of primary gliomas 显示文摘 | Kitange GJ Templeton Kristen LBA Jenkins Robert B | 2003 | Curr Opini Oncol2003，15，： | 1 |
| 3 | Cadmium uptake by barley as affected by Cd sources and pH levels显示文摘 | SINGH R B KRISTEN M | 1998 | Geoderma1998，84，： | 1 |
| 4 | Glutamine attenuates endotoxin-induced lung metabolic dysfunction:potential role of enhanced heat shock protein 70显示文摘 | Kristen D S Natalie S Anirban B | 2005 | Nutrition2005，21，： | 1 |
| 5 | Polygalacturonases:Many genes in search of a function显示文摘 | Kristen A Alan B | 1998 | Plant Physiol1998，，117： | 1 |
| 6 | Change to a standardized airway clearance protocol for children with bronchiolitis leads to improved care 显示文摘 | Kristen J Daniela P Kim B | 2014 | Journal of Pediatric Nursing2014，29，3： | 1 |
| 7 | Aerobic and cometabolic MTBE biodegradation at Navato and Port Hueneme显示文摘 | Magar V S Kristen H Christy B | 2002 | J Environ Eng2002，128，9： | 1 |
| 8 | Insuring redevelopment at contaminated urban properties显示文摘 | Wernstedt K Meyer P B Kristen R Y | 2003 | Public Works Management & Policy2003，8，2： | 1 |
| 9 | Sources and species of cryptosporidium oocysts in the wachusett reservoir watershed显示文摘 | Kristen L Jellison Harold F Hemond David B Schauer | 2002 | Appl Environ Microbiol2002，68，： | 1 |
| 10 | Chemical properties of x-3 fortified gels made of protein isolate recovered with isoelectrie solubilisation/precipitation from whole fish 显示文摘 | Reza T Sarah K B Kristen E | 2013 | Food Chemistry2013，139，： | 1 |
| 11 | Transtbrmable facultative thermophile Geobacillus stearothermophilus NUB3621 as a host strain for metabolic engineering显示文摘 | Kristen B Srebrenka R lchiro M | 2014 | Applied Microbiology and Biotechnology2014，98，15： | 1 |
| 12 | Public policies for managing urban growth and protecting open space:policy instruments and lessons learned in the United States显示文摘 | DAVID N B JENNIFER O F KRISTEN C N | 2004 | Landscape and Urban Planning2004，69，23： | 1 |
| 13 | Transcription Activator Interactions with Multiple SWI/SNF Subunits显示文摘 | Kristen E N Ahmed H H Christine E B | 2002 | Molecular and Cellular Biology2002，22，6： | 1 |
| 14 | Fibrogenesis IV,Fibrosis and inflammatory bowel disease,cellular mediators and animal models显示文摘 | Jolanta B Pucilowska Kristen L | 2000 | Am J Physiol Gastrointest Liver Physiol2000，4，279： | 1 |
| 15 | Reprogramming of pancreatic βcells in- to induced pluripotent stem cells显示文摘 | Matthias S Kristen B Konrad H | 2008 | Current Biology2008，10，： | 1 |
| 16 | Non-invasive predictors of survival in cardiac amyloidosis 显示文摘 | Amt V Kristen A Jolanta B | 2007 | Eur J Heart Failure2007，9，： | 1 |
| 17 | Brown adipose tissue regulates glucose homeostasis and insulin sensitivity显示文摘 | Stanford Kristin I Middelbeek Roeland J W Townsend Kristy L An Ding Nygaard Eva B Hitchcox Kristen M Markan Kathleen R Nakano Kazuhiro Hirshman Michael F Tseng Yu-Hua Goodyear Laurie J | 2013 | Journal of Clinical Investigation2013，，1： | 1 |
| 18 | Polygalacturonases : Many genes in search of a function 显示文摘 | Kristen A Alan B | 1998 | Plant Physiol1998，117，： | 1 |
| 19 | Atrazine mineralization potential in two wetlands显示文摘 | AndersonL Kristen Wheeler A K Robinson B J | 2002 | Water Research2002，36，19： | 1 |
| 20 | Polygalacturonases: many genes in search of a function显示文摘 | KRISTEN A ALAN B | 1998 | Plant Physiol1998，117，2： | 1 |
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