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5篇 您的检索式:作者名="Kuimova"
    题名 作者 年代 出处 被引量
1Molecular ro- tor measures viscosity of live cells via fluorescence life- time imaging显示文摘Kuimova M K Yahioglu G Levitt J A 2008Journal of the American Chemical Soci- ety2008,130,:1
2Fluorescence anisotropy of molecular rotors 显示文摘Levitt J A Chung P H Kuimova M K 2011ChemPhysOhem2011,12,3:1
3Intramolecular rotation in a porphyrin dimer controls singlet oxygen production 显示文摘KUIMOVA M K BALAZ M ANDERSON H L 2009Journal of the American Chemical Society2009,131,23:1
4Imaging intracellular viscosity of a single cell during photoinduced cell death显示文摘Kuimova M K Botchway S W Parker A W Balaz M Collins H A Anderson H L Suhling K Ogilby P R 2009Nature Chemistry2009,1,1:1
5Fluorescence lifetime imaging of molecular rotors to map microviscosity in cells显示文摘Fluorescence liftime imaging (FLIM) of modified hydrophobic bodipy dyes that act as fluorescent molecular rotors shows that the fluorescence lifetime of these probes is a function of the microviscosity of their environment. Incubating cells with these dyes, we find a punctate and continuous distribution of the dye in cells. The viscosity value obtained in what appears to be endocytotic vesicles in living cells is around 100 times higher than that of water and of cellular cytoplasm.Time-resolved fluorescence anisotropy measurements also yield rotational correlation times consistent with large microviscosity values. In this way, we successfully develop a practical and versatile approach to map the microviscosity in cells based on imaging fluorescent molecular rotors.James A. Levitt Marina K. Kuimova Gokhan Yahioglu Pei-Hua Chung Klaus Suhling David Phillips 2010Chinese Optics Letters2010,8,10:0
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