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| 1 | 坐骨神经预损伤对脊髓损伤后小鼠神经功能恢复的影响显示文摘目的研究坐骨神经预损伤对脊髓损伤后小鼠神经功能恢复的影响。方法以C57BL/6小鼠为研究对象,分为假手术组(对照组,Control),脊髓损伤(spinal cord injury, SCI)组和坐骨神经预损伤(sciatic nerve injury,SNI)组。假手术组仅移除小鼠T8-T10椎骨上棘暴露胸髓,SCI组移除小鼠T8-T10椎骨上棘暴露胸髓给予外力打击造成标准损伤,SNI组小鼠手术切断右腿坐骨神经,在预损伤7d后进行脊髓损伤。在恢复期(即脊髓损伤14d后),通过电生理实验检测运动神经传导功能,通过组织病理学检验检测组织缺损恢复、髓鞘再生及小胶质细胞的募集活化。结果电生理实验表明SNI组小鼠运动传导功能恢复明显强于SCI组;HE染色结果说明SNI组脊髓组织缺损恢复情况明显强于SNI组;以MBP为指标的免疫荧光结果显示SNI组髓鞘含量明显多于SCI组,髓鞘再生能力明显增强;以IBA-1为指标的免疫荧光结果显示SNI组小胶质细胞明显增多,坐骨神经预损伤明显增强了小胶质细胞的募集活化作用。结论坐骨神经预损伤处理可促进小鼠脊髓损伤后组织形态恢复、小胶质募集活化作用、髓鞘再生作用和神经传导功能的恢复。 | 毛东升 李怡萱 许凤燕 唐旭东 JAY PRAKASH PRASAD KUMAL 吴迪 孙亮 吴树亮 | 2019 | 解剖科学进展2019，0，5： | 4 |
| 2 | Radiiographic Analysis ofHallux Valguis 显示文摘 | 〔17〕 Yasuhito Tanaka Yoshinori Takaoura Tsukasa Kumal | 1995 | J-Bone-Joint-Surg1995，77，2： | 1 |
| 3 | Neuroprotective effect of erythropoietin on hypoxicischemic brain in jury in neonatal显示文摘 | Kumal A Ozar E Yilmaz O | 2003 | Biol Neonate2003，83，： | 1 |
| 4 | Application of inorganic carrier-based formulations of fluorescent pseudomonads and Piriformospora indica on tomato plants and evaluation of their efficacy显示文摘 | Sarma M Kumal V Saharan K | | 0，，： | 1 |
| 5 | Customer Loyalty: Toward an Integrated Conceptual Framewnrk显示文摘 | Dick Alan & Basu Kumal | 1994 | Journal of the Academy of Marketing Science1994，22，： | 1 |
| 6 | ACE inhibition versus angiotensin type 1 receptor antagonism:differential effects on PAL-1 over time显示文摘 | Brown N J Kumal S Painter CA | | 0，，06： | 1 |
| 7 | Characterization ofnickel doped CCTO: CaCu2gNio,Ti4Ot2 and CaCu;iTi39Ni0lO12 syn-thesized by semi-wet route显示文摘 | RAI A K MANDAL K D KUMAL D | 2010 | J Alloys Compd2010，491，： | 1 |
| 8 | Application of inorganic carrier-based formulations of fluorescent pseudomonads and Pir- iformospora indica on tomato plants and evaluation of their effi- cacy显示文摘 | Sarma M Kumal V Saharan K | 2011 | Journal of Applied Microbiology2011，111，： | 1 |
| 9 | 电针联合二甲双胍对创伤性脑损伤的治疗作用显示文摘目的探讨二甲双胍与电针对创伤性脑损伤(TBI)的治疗作用。方法以C57BL/6小鼠为研究对象,分为对照组(Control),TBI组,TBI+E(Electroacupuncture,E)组,TBI+M(Metformin,M)组和TBI+E+M组。对照组仅摘除颅骨,TBI组实施重物坠落法造成脑损伤,TBI+E组在损伤后第二天以电针治疗,TBI+M组在损伤后第二天以二甲双胍治疗,TBI+E+M组在损伤后第二天以电针和二甲双胍联合治疗。在TBI后7d,通过新物体识别试验检测认知功能,通过组织病理学实验检测组织缺损、小胶质细胞的募集活化和髓鞘再生。结果TBI+E+M组小鼠认知功能恢复明显强于TBI组,TBI组出现组织缺损、皮层空洞;TBI+E组、TBI+M组和TBI+E+M组小胶质细胞数目均出现降低,TBI+E+M组恢复到对照组水平,小胶质细胞的募集活化受到明显抑制;TBI+E+M组髓鞘含量明显多于TBI+E组和TBI+M组,髓鞘再生能力明显增强。结论二甲双胍联合电针治疗脑损伤改善小鼠认知功能障碍,抑制小胶质细胞的募集活化和促进髓鞘再生。 | 李怡萱 李波 唐旭东 JAY PRAKASH PRASAD KUMAL 许凤燕 孙亮 吴树亮 | 2023 | 解剖科学进展2023，29，4： | 0 |
| 10 | Passive diffusion sampling of sulfur dioxide in India: Impact assessment on arid areas显示文摘Environmental constraints have drastically limited options of sustainable developmentand have severely offset many developmental schemes. In this paper, possibilities of acidic depo-sition, as a counter measure of desertification, are analyzed. Seasonal data of ambient sulfur di-oxide, pH of rain water and soil acidity are collected for over an year and analyzed. Arid environ-ment of surrounding areas of Delhi is considered and analyzed. Though ambient sulfur depositionis well below critical level, it might not be truly indicative of plant survival in arid areas. Results maybe useful in arid area afforestation, and polluting industries relocation, which holds tremendouspotential vis-a-vis sustainable development. | S. Kumal M. Mohan R. Datta | 2002 | Science China Earth Sciences2002，45，z1： | 0 |
| 11 | Content analysis of documents using neural networks: A study of Antarctic science research articles published in international journals显示文摘Content analysis of scientific papers emanating from Antarctic science research during the 25 years period (1980-2004) has been carried out using neural network based algorithm-CATPAC. A total of 10 942 research articles published in Science Citation Indexed (SCI) journals were used for the study. Normalized co-word matrix from 35 most-used significant words was used to study the semantic association between the words. Structural Equivalence blocks were constructed from these 35 most-used words. Four-block model solution was found to be optimum. The density table was dichotomized using the mean density of the table to derive the binary matrix, which was used to construct the network map. Network maps represent the thematic character of the blocks. The blocks showed preferred connection in establishing semantic relationship with the blocks, characterizing thematic composition of Antarctic science research. The analysis has provided an analytical framework for carrying out studies on the content of scientific articles. The paper has shown the utility of co-word analysis in highlighting the important areas of research in Antarctic science. | DASTIDAR Prabir G JHA, Deepak Kumal | 2012 | Advances in Polar Science2012，23，1： | 0 |
| 12 | Preparation and cellular uptake behaviors of uniform fiber-like micelles with length controllability and high colloidal stability in aqueous media显示文摘Fragmentation/disassembly of fiber-like micelles generated by living crystalline-driven self-assembly(CDSA)is usually encountered in aqueous media,which hinders the applications of micelles.Herein,we report the generation of uniform fiber-like micelles consisting of a��Л-conjugated oligo(p-phenylenevinylene)core and a crosslinking silica shell with grafted poly(ethylene glycol)(PEG)chains by the combination of living CDSA,silica chemistry and surface grafting-onto strategy.Owing to the presence of crosslinking silica shell and the outmost PEG chains,the resulting micelles exhibit excellent dispersity and colloidal stability in PBS buffer,BSA aqueous solution and upon heating at 80℃ for 2 h without micellar fragmentation/disassembly.The micelles also show negligible cytotoxicity toward both HeLa cervical cancer and HEK239T human embryonic kidney cell lines.Interestingly,micelles with Ln of 156 nm show the“stealth”property with no significant uptake by HeLa cells,whereas some certain amounts of micelles with Ln of 535 nm can penetrate into HeLa cells,showing length-dependent cellular uptake behaviors.These results provide a route to prepare uniform,colloidally stable fiber-like nanostructures with tunable length and functions derived for biomedical applications. | Junyu Ma Chen Ma Xiaoyu Huang Pedro Henrique Hermes de Araujo Amit Kumal Goyal Guolin Lu Chun Feng | 2023 | Fundamental Research2023，3，1： | 0 |
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