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| 1 | Gastrointestinal stromal tumor presenting with prominent calcification显示文摘We present a rare case of a gastrointestinal stromal tumor (GIST) in the stomach with prominent calcifica-tion at presentation. A 61-year-old woman visited our hospital because of epigastric discomfort. A spherical calcified lesion with a diameter of about 30 mm was incidentally shown in the left upper quadrant on an abdominal X-ray. Computed tomography demonstrated that the tumor was growing from the upper gastric body, with calcification in the peripheral ring area. A laparoscopic partial gastrectomy was performed, and the resected specimen revealed a well-circumscribed tumor with exophytic growth from the gastric muscularis propria. Microscopic examination revealed spindle- shaped tumor cells with calcification and hemorrhage. Additionally, positive immunoreactivity of the tumor to KIT and CD34 and a low mitotic index resulted in the diagnosis of very low risk GIST. There are a few case reports of heavily calcified GIST, although solitary or punctate calcification of primary GIST has been reported in several case series. Dystrophic calcification of necrotic or degenerative tissue is the supposed cause of primary calcified GISTs. In contrast, appearance of calcification after administration of imatinib mesylate, which may be one indicator of disease response, is possibly caused by a different mechanism. | Naoki Izawa Takeshi Sawada Ryuichi Abiko Daisuke Kumon Mami Hirakawa Mika Kobayashi Nobuyuki Obinata Masahito Nomoto Tadateru Maehata Shun-ichi Yamauchi Takefumi Kouro Takashi Tsuda Satoshi Kitajima Hiroshi Yasuda Keiichi Tanaka Ichiro Tanaka Masahiro Hoshikawa Masayuki Takagi Fumio Itoh | 2012 | World Journal of Gastroenterology2012，18，39： | 2 |
| 2 | Emission of BTEX and PAHs from molding sands with furan cold setting resins containing different contents of free furfuryl alcohol during production of cast iron显示文摘At present, furan resin is the largest selling no-bake system of moulding sands. The most commonly used furan no-bake binders(FNB) are condensation products of furfuryl alcohol(FA) urea, formaldehyde and phenol. They are generally cured by exposure to organic sulfonic acids. FNB provide excellent mold and core strength, cure rapidly and allow the sand to be reclaimed at fairly high yields, generally 75%-80%, especially in applications where due allowance is made for the need to keep total sulfur content below 0.1%. However, due to probable carcinogenic properties of furfuryl alcohol, the EU Directive limits the content of this substance(in a monomer form in resin) to 25%. The classification of furfuryl alcohol and the resulting furan resin products has changed from 'harmful' to 'toxic by inhalation'. The aim of this study was to determine the effect of free furfuryl alcohol content in the resin on the emission of harmful substances from the BTEX(Benzene Toluene Ethylbenzene & Xylene) and PAHs(polycyclic aromatic hydrocarbon) group exposed to high temperature and how it affects the emissions allowance of reclaimed sand in the matrix. Three resins from a leading manufacturer were examined, which contain a free furfuryl alcohol content of 71%-72%, about 50% and < 25%, respectively. The hardener for each resin was 65% aqueous solution of paratoluenesulfonic acid. Tests were carried out in semi-industrial conditions where liquid cast-iron was poured into sample sand mold at 1,350 °C. The matrix of the studied sands was reclaimed in the amount of 0, 50%, 100%, respectively.With the increase of free furfuryl alcohol content, the volume of evolved gases decreased. For all resins the main component from the BTEX group dominating in the emitted gases was benzene; however toluene also appeared in the amount of a few percentages. In contrast, ethylbenzene and xylenes occurred only in the gases emitted from resin-bonded sands with the largest furfuryl alcohol content. The increase in the share of reclaimed sands resulted in very significant increase in the volume of gas generated and participation of benzene in these gases. In terms of emission of compounds from the PAHs group virtually for all resins, the total content of these substances was comparable(within the limits of error). The main components were: fluoranthene, pyrene and benzo(a) anthracene. | Mariusz Holtzer Sylwia Zymankowska–Kumon Angelika Kmita Rafal Dańko | 2015 | China Foundry2015，12，6： | 2 |
| 3 | Serum paraoxonase activity decreases in rheumatoid arthritis 显示文摘 | TANIMOTO N KUMON Y SUEHIRO T | 2003 | Life Sciences2003，72，25： | 1 |
| 4 | Potential of adenovirus‐mediated REIC / Dkk ‐3 gene therapy for use in the treatment of pancreatic cancer显示文摘 | Daisuke Uchida Hidenori Shiraha Hironari Kato Teruya Nagahara Masaya Iwamuro Junro Kataoka Shigeru Horiguchi Masami Watanabe Akinobu Takaki Kazuhiro Nouso Yasutomo Nasu Takahito Yagi Hiromi Kumon Kazuhide Yamamoto | 2014 | J Gastroenterol Hepatol2014，，5： | 1 |
| 5 | Delayed facial palsy aftermicrovaseular decompression for hernifacial spasm due to reactivation of varicella2zoster virus 显示文摘 | Furukawa K Sakoh M Kumon Y | 2003 | No Shinkei Geka2003，31，8： | 1 |
| 6 | Three-dimensional imaging for presentation of the causative vessels in patients with hemifacial spasm and trigeminal neuralgia显示文摘 | KUMON Y SAKAKI S KOHNO K | 1997 | Surg Neurol1997，47，2： | 1 |
| 7 | Surgical management of brainstem cavernomas:selection of approaches and microsurgical techniques显示文摘 | Ohue S Fukushima T Kumon Y | 2010 | Neurosurg Rev2010，33，3： | 1 |
| 8 | Prostate cancer gene therapy显示文摘 | Nasu Y Kumon H | 2005 | Nippon Rinsho2005，63，3： | 1 |
| 9 | Anatomy of the caudate lobe with special reference to portal vein and bile dact显示文摘 | Kumon M | 1985 | Acta Hepatol JPH1985，26，1： | 1 |
| 10 | Evaluation of prognostic factors following expansive laminoplasty for cervical spinal stenosis myelopathy显示文摘 | Kohno K Kumon Y Oka Y | 1997 | Surg Neurol1997，48，3： | 1 |
| 11 | Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia 显示文摘 | Kumon Y Kim SC Tompkins P | 2000 | J Neurosurg2000，92，： | 1 |
| 12 | PTEN gene transfer suppresses the invasive potential of human ma- lignant gliomas by regulating cell invasion-related molecules显示文摘 | Furukawa K Kumon Y Harada H | 2006 | Int J Oncol2006，29，1： | 1 |
| 13 | Double-folded monopole antenna using parallel line or coaxial cable显示文摘 | Tsukiji T Kumon Y Yamasaki M | 2002 | IEE Proceedings of Microwaves Antennas and Propagation2002，149，1： | 1 |
| 14 | Intercellular adhesion molecule- 1 expression on the hepatocyle membrane of patients with chronic hepatitis B and C显示文摘 | Horiike N Onji M Kumon t | 1993 | Liver1993，13，1： | 1 |
| 15 | Prostate cancer gene therapy 显示文摘 | Nasu Y Abzrzua F Kumon H | 2005 | Nippon Rinsho2005，63，12： | 1 |
| 16 | Combination effect of fosfomycin and ofloxacin against Pseudomonas aeruginosa growing in a biofilm显示文摘 | Kumon H Ono N Iida M | 1995 | Antimicrob Agents Chemother1995，39，5： | 1 |
| 17 | Increase in P53 protein expression following cortical infarction in the spontaneously hypertensive rat显示文摘 | Ohta S Kumon Y | 1999 | Brain Res1999，837，： | 1 |
| 18 | A sandwich cup method for the penetration assay of antimicrobial agents through Pseudomonas exopolysaccharides显示文摘 | Kumon H Tomochika K Matunaga T | 1994 | Microbiol Immunol1994，38，8： | 1 |
| 19 | Combination effect of fosfomycin and ofloxacin againsl pseudomonas aetugi nosa growing in a biofilm显示文摘 | kumon H Ono N Lida M | 1995 | Antimicrob Agents Chemother1995，39，： | 1 |
| 20 | Intercellular adhesion molecule- 1 expression on the hepatocyte meo mbrane of patients with chronic hepatitis B and C 显示文摘 | Horiike N Onji M Kumon I | 1993 | Liver1993，13，： | 1 |
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