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| 1 | A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells显示文摘CCL5 是响应压力信号在有免疫力、非有免疫力的房间的一个宽数组表示的 CC chemokine 家庭的一个成员。有先进人的乳癌的 CCL5 表示相互关联。然而,它行动的功能的意义和模式没被建立。这里,我们证明 CCL5 缺乏的老鼠对高度好攻击的、三元组否定的乳房的肿瘤生长抵抗。造血的 CCL5 在这显型是主导的。造血的 CCL5 的缺席由积累 Ly6C +/Gr-1+, 的异常产生导出 myeloid 的 suppressor 房间(MDSC )> 嗨有损害能力到的 和 Ly6G + MDSC 压制 CD8 + T 房间的 cytotoxicity。CCL5 的这些性质在 orthotopic 和自发的乳房的肿瘤被观察。CCL5 的调停抗体的全身的封锁禁止肿瘤前进并且对非产生免疫性的肿瘤提高治疗学的种痘的功效。CCL5 也帮助维持人的 MDSC 的抑制免疫力的能力。我们的学习揭开经由与导出肿瘤的刺激殖民地的因素在合作在骨头髓产生 MDSC 支持乳房的肿瘤前进的造血地导出的 CCL5 的一项新奇、 chemokine 独立的活动。学习在在造血的分隔空间和肿瘤壁龛之间的相互影响上打开可观的灯。因为在正常生理学的这个分子的明显的非必需的性质, CCL5 可以象有 MDSC 渗入的重要数量的大量稳固的肿瘤一样为乳癌在免疫疗法代表一个优秀治疗学的目标。 | Yan Zhang Dandan Lv Ha-Jeong Kim Robert A Kurt Wen Bu Yi Li Xiaojing Ma | 2013 | Cell Research2013，23，3： | 9 |
| 2 | A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse显示文摘 | Erhe Gao Yong Hong Lei Xiying Shang Z. Maggie Huang Lin Zuo Matthieu Boucher Qian Fan J. Kurt Chuprun Xin L. Ma Walter J. Koch | 2010 | Circulation Research2010，，12： | 1 |
| 3 | Low-grade in traosseous osteosarcoma显示文摘 | Kurt MA Unni KK Mc Leod RA | | 0，，： | 1 |
| 4 | Neurodegenerative changes associated with beta- amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes 显示文摘 | Kurt MA Davies DC Kidd M | 2001 | Exp Neurol2001，171，： | 1 |
| 5 | Essential Role of Caveolin-3 in Adiponectin Signalsome Formation and Adiponectin Cardioprotection显示文摘 | Yajing Wang Xiaoliang Wang Jean-Fran?ois Jasmin Wayne Bond Lau Rong Li Yuexin Yuan Wei Yi Kurt Chuprun Michael P. Lisanti Walter J. Koch Erhe Gao Xin-Liang Ma | 2012 | Arteriosclerosis Thrombosis and Vascular Biology2012，，4： | 1 |
| 6 | Female Sexual Function After Pure Transvaginal Appendectomy: A Cohort Study显示文摘 | Daniel Solomon MD Rachel Lentz MD Andrew J. Duffy MD Robert L. Bell MD MA Kurt E. Roberts MD | 2012 | Journal of Gastrointestinal Surgery2012，，1： | 1 |
| 7 | Hyperphosphorylated tau and paird helical filament- like structures in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1transgenes显示文摘 | Kurt MA Davies DC Kidd M | 2003 | Neurobiol Dis2003，14，： | 1 |
| 8 | A practical approach to glomerular filtration rate mesurements; Creatinine clearance estimation using cimetidine显示文摘 | Serdar MA Kurt I Ozcelik F | 2001 | Am Clin Lab Seien2001，31，： | 1 |
| 9 | Rhodenthoside A, a new type of aeylated seeolrldold glyeoside from Gentiana rhodentha 显示文摘 | Ma WG Fruzzati N Kurt H | 1994 | Helvetiea Chlmimiea Aeta1994，77，6： | 1 |
| 10 | Low-grade in traosseous osteosarcoma显示文摘 | Unni KK Me kod RA | 1990 | Cancer1990，65，： | 1 |
| 11 | The peri-microvascular edema in hippocampal CA1 area in a rat model of sepsis显示文摘 | Kafa IM Ari I Kurt MA | 2007 | Neuropathology2007，27，3： | 1 |
| 12 | Oxidant scavenger function of ambroxol in vitro: a comparison withN-acetylcysteine显示文摘 | Adrian Gillissen Birgit Sch?rling Ma?gorzata Jaworska Almut Bartling Kurt Rasche Gerhard Schultze-Werninghaus | 1996 | Research in Experimental Medicine1996，，1： | 1 |
| 13 | Neurodegenerative changes asso- ciated with beta - amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin - 1 transgenes 显示文摘 | Kurt MA Davies DC Kidd M | 2001 | Exp Neurol2001，171，： | 1 |
| 14 | An Integrative Genomics Approach Identifies Activation of Thioredoxin/Thioredoxin Reductase-1-Mediated Oxidative Stress Defense Pathway and Inhibition of Angiogenesis in Obese Nondiabetic Human Subjects显示文摘 | Swapan K. Das Neeraj K. Sharma Sandra J. Hasstedt Ashis K. Mondal Lijun Ma Kurt A. Langberg Steven C. Elbein | 2011 | The Journal of Clinical Endocrinology & Metabolism2011，，8： | 1 |
| 15 | Theoretical study on the isomerization reaction of fluorine substituted disilene显示文摘For the isomerization reaction of monofluoro-disilene,the geometrical structures of reac-tant,product and transition state have been optimized and energy constant,vibrational frequencycalculated.By means of the statistical thermodynamics and Eyring’s transition state theory,theequilibrium constant,rate constant and heat of isomerization have also been computed.Hence,this reaction has been analysed completely. | JU,Guan-Zhi MA,Wan-Yong Theoretical Institute of Chemistry,Shandong University,Jinan 250100CHRISTOFFEL,Kurt Chemistry Department,Augustana College,Rock Island IL 61201,USA | 1990 | Chinese Journal of Chemistry1990，8，3： | 0 |
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