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| 1 | Osteopontin is a biomarker for early autoimmune uveoretinitis显示文摘Osteopontin(OPN)is an extracellular matrix protein with a diverse range of functions,including roles in cell adhesion,migration,and immunomodulation,which are associated with the modulation of neuroinflammation in the central nervous system.The present study was performed to evaluate the involvement of OPN in the eyes of an experimental autoimmune uveoretinitis(EAU)model.The EAU model was developed by immunization of Lewis rats with interphotoreceptor retinoid-binding protein.The results showed the OPN level was remarkably upregulated in the eye of EAU rats on day 9 post-immunization.The level of CD44,a ligand of OPN,was increased in the ciliary body of EAU rats.Furthermore,OPN was also detected in the ciliary body and activated microglia/macrophages in the EAU retina.The results suggest that OPN was significantly upregulated in the eyes of EAU rats,and that it may be useful as an early biomarker of ocular autoimmune diseases.All animal experiments were approved by the Institutional Animal Care and Use Committee of Jeju National University(approval No.2020-0012)on March 11,2020. | Jeongtae Kim Meejung Ahn Yuna Choi Jiyoon Chun Kyungsook Jung Akane Tanaka Hiroshi Matsuda Taekyun Shin | 2022 | Neural Regeneration Research2022，17，7： | 3 |
| 2 | Phenotypic alterations of petal and sepal by ectopic expression of a rice MADS box gene in tobacco显示文摘 | Hong-Gyu Kang Yoo-Sun Noh Yong-Yoon Chung Michael A. Costa Kyungsook An Gynheung An | 1995 | Plant Molecular Biology1995，，1： | 1 |
| 3 | Alteration of floral organ identity in rice through ectopic expression of OsMADS16显示文摘 | Sichul Lee Jong-Seong Jeon Kyungsook An Yong-Hwan Moon Sanghee Lee Yong-Yoon Chung Gynheung An | 2003 | Planta2003，，6： | 1 |
| 4 | Computational analysis of hydrogen bonds in protein–RNA complexes for interaction patterns显示文摘 | Hyunwoo Kim Euna Jeong Seong-Wook Lee Kyungsook Han | 2003 | FEBS Letters2003，，2： | 1 |
| 5 | Generation of T-DNA Tagging Lines with a Bidirectional Gene Trap Vector and the Establishment of an Insertion-Site Database显示文摘 | Choong-Hwan Ryu Jung-Hwa You Hong-Gyu Kang Junghe Hur Young-Hea Kim Min-Jung Han Kyungsook An Byoung-Chull Chung Choon-Hwan Lee Gynheung An | 2004 | Plant Molecular Biology2004，，4： | 1 |
| 6 | Prediction of common folding structures of homologous RNAs 显示文摘 | Han Kyungsook Kim Hongjin | 1993 | Nucleic Acids Re- search1993，21，5： | 1 |
| 7 | SIRT1 regulates tyrosine hydroxylase expression and differentiation of neuroblastoma cells via FOXO3a显示文摘 | Min-Ju Kim Kyungsook Ahn Seong-Hoon Park Hong-Jun Kang Bong Geom Jang Soo-Jin Oh Sun-Mee Oh Yu-Jin Jeong Jee-In Heo Jun-Gyo Suh Soon Sung Lim Yoon-Jung Ko Sung-Oh Huh Sung Chan Kim Jae-Bong Park Jaebong Kim Jong-Il Kim Sangmee Ahn Jo Jae-Yong Lee | 2009 | FEBS Letters2009，，7： | 1 |
| 8 | KSMIN' s: Knockout switch-based multstage interconnection networks for high-speed packet switching显示文摘 | Young Man Kim Kyungsook Y Lee | 1995 | IEEE Trans Commun1995，43，8： | 1 |
| 9 | Characterization of tobacco MADS-box genes involved in floral initiation 显示文摘 | Seonghoe J Kyungsook A Shinyoung L | 2002 | Plant Cell Physiol2002，43，1： | 1 |
| 10 | Old stellar population synthesis:new age and mass estimates for Mayall II = G1显示文摘Mayall II = G1 is one of the most luminous globular clusters (GCs) in M31. Here, we determine its age and mass by comparing multicolor photometry with theoretical stellar population synthesis models. Based on farand near-ultraviolet GALEX photometry, broad-band UBV RI, and infrared JHKs 2MASS data, we construct the most extensive spectral energy distribution of G1 to date, spanning the wavelength range from 1538 to 20 000 A?. A quantitative comparison with a variety of simple stellar population (SSP) models yields a mean age which is consistent with G1 being among the oldest building blocks of M31 and having formed within ~1.7Gyr after the Big Bang. Irrespective of the SSP model or stellar initial mass function adopted, the resulting mass estimates (of order 107M ) indicate that G1 is one of the most massive GCs in the Local Group. However, we speculate that the cluster's exceptionally high mass suggests that it may not be a genuine GC. Our results also suggest that G1 may contain, on average, (1.65±0.63)×102L far-ultraviolet-bright,hot, extreme horizontal-branchstars, depending on the adopted SSP model. In addition, we demonstrate that extensive multi-passband photometry coupled with SSP analysis enables one to obtain age estimates for old SSPs that have similar accuracies as those from integrated spectroscopy or resolved stellar photometry, provided that some of the free parameters can be constrained independently. | Jun Ma Richard de Grijs Zhou Fan Soo-Chang Rey Zhen-Yu Wu Xu Zhou Jiang-Hua Wu Zhao-Ji Jiang Jian-Sheng Chen Kyungsook Lee Sangmo Tony Sohn | 2009 | Research in Astronomy and Astrophysics2009，9，6： | 0 |
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