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| 1 | Current approaches to reduce or eliminate mitochondrial DNA mutations显示文摘Mitochondrial DNA(mt DNA)mutations have been implicated in a broad range of disorders which severely affect human health(Wallace,1999).Some drugs have been developed to slow down pathological changes of mitochondrial disorders.However,there is no effective treatment for patients with mt DNA mutations.mt DNA is less protected and has fewer repair mechanisms than nuclear DNA(n DNA).Such a reality results in a much higher | Liang Yang Tingfang Mei Xiaobing Lin Haite Tang Yi Wu Rui Wang Jinglei Liu Zahir Shah Xingguo Liu | 2016 | Science China(Life Sciences)2016，59，5： | 3 |
| 2 | The comparative efficacy of ezetimibe added to atorvastatin 10 mg versus uptitration to atorvastatin 40 mg in subgroups of patients aged 65 to 74 years or greater than or equal to 75 years显示文摘有年龄的背景冠的心疾病(CHD ) 风险增加;然而类脂化合物阴沉的治疗是显著地在病人的 under-utilized > 65 年。目的是评估安全,在更老的病人的类脂化合物阴沉的治疗的功效与 atorvastatin 对待 10 mg + ezetimibe 10 mg (EZ/Atorva ) 对增加 atorvastatin 剂量到 40 mg。方法病人有动脉粥样硬化患者的 65 年脉管的疾病(LDL-C 1.81 mmol/L ) 或在为冠的心的高风险,疾病(LDL-C 2.59 mmol/L ) 为 12 wk 对 uptitration 被使随机化到 EZ/Atorva 到为 6 wk 的 20 mg 由 atorvastatin 跟随了的 atorvastatin 为 6 wk 的 40 mg。在完成 prespecified LDL-C 层次的 LDL-C 和另外的类脂化合物参数和百分比病人的百分比变化在 12 wk 以后被估计。结果 EZ/Atorva 在病人在大多数类脂化合物参数对 atorvastatin 的 uptitration 生产了更大的减小 75 年(n = 228 ) ,与病人通常一致 6574 年(n = 812 ) 。更多的病人在 6 wk 并且在病人在两个年龄组与联合治疗对 monotherapy 完成了 LDL-C 目标在 12 wk 的 75 年。在 12 wk,更多的病人 75 年与 monotherapy 对联合治疗完成了 LDL-C 目标。EZ/Atorva 在大多数类脂化合物生产了更有利的改进对加倍或 quadrupling 在病人的 atorvastatin 剂量 75 年,与在病人的调查结果通常一致 6574 年。我们的结果扩大了证明 ezetimibe 增加了 statin 的以前的调查结果的结论为在病人改进类脂化合物侧面提供了一种通常容忍得好的治疗学的选择 65 ~ 74 年和 75 岁。 | Ori Ben-Yehuda Nanette K. Wenger Christian Constance Franklin Zieve Mary E. Hanson Jian-Xin Lin Arvind K. Shah Charlotte Jones-Burton Andrew M. Tershakovec | 2011 | Journal of Geriatric Cardiology2011，8，1： | 2 |
| 3 | Plastic biliary stent patency in patients with locally advanced pancreatic adenocarcinoma receiving downstaging chemotherapy显示文摘 | Phillip S. Ge Christopher M. Hamerski Rabindra R. Watson Srinadh Komanduri Birtukan B. Cinnor Kiran Bidari Jason B. Klapman Cui L. Lin Janak N. Shah Sachin Wani Timothy R. Donahue V. Raman Muthusamy | 2014 | Gastrointestinal Endoscopy2014，，： | 2 |
| 4 | Increasing anaphylaxis hospi-talizations in the first 2 decades of life:New York State,1990-2006显示文摘 | Lin R Y Anderson A S Shah S N | 2008 | Ann Allergy Asthma Immunol2008，101，4： | 1 |
| 5 | Cyclooxygenase-2:a novel molecular target for the prevention and treatment of head and neck cancer 显示文摘 | Lin DT Subbaramaiah S Shah JP | 2002 | Head Neck2002，792，： | 1 |
| 6 | Cyclooxygenase-2:a novel molecular target for the prevention and treatment of head and neck cancer显示文摘 | Lin DT Subbaramaiah K Shah JP | 2002 | Head Neck2002，24，： | 1 |
| 7 | RNA-Seq of human neurons derived from iPS cells reveals candidate long non-coding RNAs involved in neurogenesis and neuropsychiatric disorders 显示文摘 | Lin M Pedrosa E Shah A | 2011 | PloS One2011，6，23： | 1 |
| 8 | Parametric Design of Anchoring Packaging Machine Based on Pro/E Secondary Development Technology显示文摘 | SHAH Li-jun MU Lin | 2010 | Mobile Congress2010，，3： | 1 |
| 9 | Improving modified Rankin scale assessment with a simplified questionnaire显示文摘 | Bruno A Shah N Lin C | 2010 | Stroke2010，41，： | 1 |
| 10 | Summary of invasive pneumo-coccal disease burden among children in the Asia-Pacific region显示文摘 | Lin TY Shah NK Brooks D | 2010 | Vaccine2010，28，48： | 1 |
| 11 | Pooled Analyses of Effects on C-Reactive Protein and Low Density Lipoprotein Cholesterol in Placebo-Controlled Trials of Ezetimibe Monotherapy or Ezetimibe Added to Baseline Statin Therapy显示文摘 | Thomas A. Pearson Christie M. Ballantyne Enrico Veltri Arvind Shah Steven Bird Jianxin Lin Elizabeth Rosenberg Andrew M. Tershakovec | 2009 | The American Journal of Cardiology2009，，3： | 1 |
| 12 | Outcomes in patients hospitalized for periapical abscess in the United States: An analysis involving the use of a nationwide inpatient sample 显示文摘 | Allareddy V Lin CY Shah A | 2010 | JAmDentAssoc2010，141，9： | 1 |
| 13 | Increasing anaphylaxis hospitalizations in the first 2 decades of life:New York State,1990–2006显示文摘 | Lin R Y Anderson A S Shah S N | 2008 | Ann Allergy Asthma Immunol2008，101，38： | 1 |
| 14 | Consistency of extended-release niacin/laro- piprant effects on Lp (a),ApoB,non-HDL-C,ApoAt,and ApoB/ApoAl ratio across patient subgroups 显示文摘 | Bays HE Shah A Lin J | 2012 | American Journal of Cardiovascular Drugs2012，12，3： | 1 |
| 15 | Summary of invasive pneumococcal disease burden among children in the Asia-Pacific region显示文摘 | Lin TY Shah NK Brooks D | 2010 | Vaccine2010，28，48： | 1 |
| 16 | Size dependency of nanocrystalline TiO 2 on its optical property and photocatalytic reactivity exemplified by 2-chlorophenol显示文摘 | H. Lin C.P. Huang W. Li C. Ni S. Ismat Shah Yao-Hsuan Tseng | 2006 | Applied Catalysis B Environmental2006，，1： | 1 |
| 17 | Pancreaticoduodenectomy for pancreatic head cancer: PPPD versus Whipple procedure显示文摘 | Lin PW Shah YS Lin Y J | 2005 | Hepatogastroenterology2005，52，65： | 1 |
| 18 | Summary of invasive pneumococcal disease burden among children in the Asia Pacif- ic region显示文摘 | Lin T Y Shah N K Brooks D | 2010 | Vaccine2010，28，48： | 1 |
| 19 | Upregulated expression of miR-1/miR-206 in a rat model of myocardial infarction 显示文摘 | Shah ZX Lin QX Fu YH | 2009 | Biochem Bio pt y s Res Comrnun2009，381，4： | 1 |
| 20 | Cyclooxygenase-2:a novel molecular target for the prevention and treatment of head and neck cancer显示文摘 | Lin DT Subbaramaiah K Shah JP | 2002 | Head Neck2002，24，： | 1 |
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