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| 1 | Enhancing the specificity of T-cell cultures for adoptive immunotherapy of cancer显示文摘 | Connie PM Duong Jennifer A Westwood Linda J Berry Phillip K Darcy Michael H Kershaw | 2011 | Immunotherapy2011，，1： | 1 |
| 2 | Effects of post harvest storage and dormancy status on ABA content,metabolism,and expression of genes involved in ABA biosynthesis and metabolism in potato tuber tissues显示文摘 | Luis D B Donna K Linda H | | 0，，45： | 1 |
| 3 | An emergency evacuation planning model for special needs populations using public transit systems 显示文摘 | Evangelos I K Linda H Alicia B | 2012 | Journal of Public Transportation2012，15，2： | 1 |
| 4 | Relation of frequency and severity of mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failure显示文摘 | Benjamin H Trichon G.Michael Felker Linda K Shaw Christopher H Cabell Christopher M O’Connor | 2003 | The American Journal of Cardiology2003，，5： | 1 |
| 5 | FOLFIRI3-aflibercept in previously treated patients with metastatic colorectal cancer显示文摘AIM To evaluate the efficacy and safety of the modified FOLFIRI3-aflibercept as second-line therapy in patients with metastatic colorectal cancer.METHODS This is a retrospective multicenter cohort, evaluating the efficacy and safety of the association of aflibercept with FOLFIRI3(day 1: aflibercept 4 mg/kg, folinic acid 400 mg/m^2, irinotecan 90 mg/m^2, 5-fluorouracil infusion 2400 mg/m^2 per 46 h; day 3: irinotecan 90 mg/m^2) in patients with previously treated metastatic colorectal cancer. The primary endpoint was overall response rate(ORR). Secondary endpoints were disease control rate(DCR), progression-free survival(PFS), overall survival(OS), and safety.RESULTS Among 74 patients treated in four French centers, nine were excluded due to prior use of aflibercept(n = 3), more than one prior treatment line in irinotecanna?ve patients(n = 3), and inadequate liver function(n = 3). In the 'irinotecan-na?ve' patients(n = 30), ORR was 43.3% and DCR was 76.7%. Median PFS and OS were 11.3 mo(95%CI: 6.1-29.0) and 17.0 mo(95%CI: 13.0-17.3), respectively. The most common(> 5%) grade 3-4 adverse events were diarrhea(37.9%), neutropenia(14.3%), stomatitis and anemia(10.4%), and hypertension(6.7%). In the 'pre-exposed irinotecan' patients(n = 35), 20(57.1%) received ≥ 2 prior lines of treatment. ORR was 34.3% and DCR was 60.0%. Median PFS and OS were 5.7 mo(95%CI: 3.9-10.4) and 14.3 mo(95%CI: 12.8-19.5), respectively.CONCLUSION Minimally modified FOLFIRI has improvement dramatically the FOLFIRI3-aflibercept efficacy, whatever prior use of irinotecan. A prospective randomized trial is warranted to compare FOLFIRI-aflibercept to FOLFIRI3-aflibercept. | CANDice Carola Fran?ois Ghiringhelli Stefano Kim Thierry ANDré Juliette Barlet Le?la Bengrine-Lefevre Hélène Marijon Marie-Line Garcia-Larnicol Christophe Borg Linda Dainese Nils Steuer Hubert Richa Magdalena Benetkiewicz Annette K Larsen Aimery de Gramont Benoist Chibaudel | 2018 | World Journal of Clinical Oncology2018，9，5： | 1 |
| 6 | Evaluation of the effect of culture matrices on induction of CYP3A isoforms in cultured porcine hepatocytes显示文摘 | VINAYAK P H LINDA K H GREGORY J B | 2000 | Chemico-Biological Interactions2000，127，： | 1 |
| 7 | Biocompatible initiators for lactide polymerization显示文摘 | Rachel H Platel Linda M Hodgson Charlotte K Williams | | 0，，01： | 1 |
| 8 | Conference abstracts: endotracheal Suctioning how deep is too deep 显示文摘 | Linda H Baldwin K Bielecki P et at | 2005 | Clinical Nurse Specialist2005，19，2： | 1 |
| 9 | Effects of postharvest storage and dormancy status on ABA content,metabolism, and expres- sion of genes involved in ABA biosynthesis and metabolism in potato tuber tissues显示文摘 | Luis D B Donna K Linda H | 2006 | Plant Molecular Biology2006，61，： | 1 |
| 10 | Hoffmann Aromatic Comound Degradation in Water Using Combination of Sonolysis and Ozonolysis显示文摘 | Linda K W Frank H L Michael R | 1998 | Environ Sci Technol1998，32，18： | 1 |
| 11 | A new hydrophilic softer显示文摘 | LINDA D K GRIFFIN E H | 2000 | Textile Asia2000，，50： | 1 |
| 12 | Improved allelic exchange vectors and their use to analyze 987P fimbria gene expression 显示文摘 | Robert A E Linda H K Dieter M S | 1998 | Gene1998，207，： | 1 |
| 13 | Electrochemical incineration of 4-chlorophenol and the identification of products and intermediates mass spectrometry显示文摘 | Steve K J Linda L H Feng Jianren | 1999 | Environ Sci & Technol1999，，33： | 1 |
| 14 | Kinetics and mechanism of pentachlorophenol degradation by sonication, ozonation, and sonolytic ozonation 显示文摘 | LINDA K W NOAH M MICHAEL R H | 2000 | Environ Sci Technol2000，34，7： | 1 |
| 15 | Effects of postharvest storage and dormancy status on ABA content, Metabolism,and expression of genes involved in ABA biosynthesis and metabo lism in potato tuber tissues显示文摘 | Luis D B Donna K Linda H | 2006 | Plant Molecular Biology2006，61，45： | 1 |
| 16 | Relation of frequency and severity of mitral regurgitation to survival among patients with left ventricular systolic dysfunction and heart failure显示文摘 | Benjamin H Trichon G.Michael Felker Linda K Shaw Christopher H Cabell Christopher M O'Connor | 2003 | The American Journal of Cardiology2003，，5： | 1 |
| 17 | Aromatic compound degradation in water using a combination of sonolysis and ozonolysis显示文摘 | Weavers Linda K Ling Frank H Hoffmann Michael R | 1998 | Environ Sci & Technol1998，32，18： | 1 |
| 18 | Oxidative stress response of a recombinant Aspergillus niger to exogenous menadione and H202 addition显示文摘 | Michaela K Linda M H Brian M | 2002 | Enzyme Microb Technol2002，30，3： | 1 |
| 19 | Nurse staffing and education and hospital mortality in nine European countries: a retrospective observational study显示文摘 | Linda H Aiken Douglas M Sloane Luk Bruyneel Koen Van den Heede Peter Griffiths Reinhard Busse Marianna Diomidous Juha Kinnunen Maria Kózka Emmanuel Lesaffre Matthew D McHugh M T Moreno-Casbas Anne Marie Rafferty Rene Schwendimann P Anne Scott Carol Tishel | 2014 | The Lancet2014，，： | 1 |
| 20 | Changes in nerve growth receptor-like immunoreactivity in the spinal cord after ventral funiculus lesion in adult cats显示文摘 | Risling M Fried K Linda H | 1992 | J Neurocytol1992，21，： | 1 |
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