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| 1 | Establishment of a Core Collection for the Chinese annual wild soybean (Glycine Soja)显示文摘With more than 6000 accessions collected from across China, the Chinese National Crop Gene Bank (CNCGB) holds the largest collection of annual wild soybean (Glycine Soja) germplasm in the world. To facilitate the management and utilization of these germplasm collections, it is important to establish a Core Collection. This study compares five sampling strategies, namely random, constant, proportional, logarithmic and genetic diversity-based, to establish a Core Collection for the annual wild soybean germplasm. Among the strategies evaluated, the genetic di- versity-based was found to be the simplest and most efficient. Using hierarchical classification and cluster analysis, in the genetic diversity diversity-based strategy, 652 accessions, accounting for 10.65% of the total 6172 accessions, were se- lected out to represent the total accessions. The established Core Collection has the following features: (i) the 21 de- scriptors observed in the entire collection were compared by the Core Collection, all 18 quality characters of entire collec- tion were preserved by core collection, and coincidence rate of average was 98.4%; (ii) the variant of 13 descriptors of the two collections was very similar, with the coincidence index being 0.96; (iii) the coincidence rate of genetic diversity be- tween the two collections was 81.38% DNA alleles; (iv) the geographic distribution pattern of core collection was the same as the entire collection; (v) molecular marker analysis by 20 SSR primer pairs on 299 accessions showed that the Core Collection covered 83.64% of the entire collection. It thus is concluded that the established Core Collection is rep- resentative and will be a valuable entry point for better evaluation and more efficient utilization of the genetic re- sources available in the annual wild soybean germplasm bank. | ZHAOLimei DONGYingshan LIUBao HAOShui WANGKejing LIXianghua | 2005 | Chinese Science Bulletin2005，50，10： | 4 |
| 2 | Cost-utility analysis of the newly recommended adjuvant chemotherapy for resectable gastric cancer patients in the2011 Chinese National Comprehensive Cancer Network(NCCN)Clinical Practice Guidelines in Oncology:Gastric Cancer显示文摘 | Chongqing T Liubao P Xiaohui Z | 2014 | Pharmacoeconomics2014，32，3： | 1 |
| 3 | The clinical application of zoledronic acid显示文摘 | Peng Liubao Cui Wei | 2007 | Zhong Guo Xin Yao Yu Lin Chuang Za Zhi2007，26，3： | 1 |
| 4 | The clinical application of zoledronic acid显示文摘 | Peng Liubao Cui Wei | 2007 | Zhong Guo Xin Yao Yu Lin Chuang Za Zhi2007，26，3： | 1 |
| 5 | Cost-u- tility analysis of the newly recommended adjuvant chemothera- py for resectable gastric cancer patients in the 2011 Chinese National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines in Oncology: Gastric Cancer显示文摘 | TAN Chongqing PENG Liubao ZENG Xiaohui etal | 2014 | Pharmaco- economics2014，32，3： | 1 |
| 6 | National Comprehensive Cancer Network:Clinical Practice Guidelines in Oncology:Gastric Cancer显示文摘 | Chongging T Liubao P Xiaobao Z | 2014 | Pharm-aceconom-ics2014，32，3： | 1 |
| 7 | Cost-effective- ness analysis of adjuvant therapy for operable breast can- cer from a Chinese perspective: doxorubicin plus cyclo- phosphamide versus docetaxel plus cyclophosphamide显示文摘 | Liubao P Xiaomin W Chongqing T | 2009 | Pharmacoeconomics2009，27，10： | 1 |
| 8 | Studies on the apoptosis of autonomic neuron in streptozotocin-induced diabetic rats显示文摘Objective: The aim of the study was to investigate apoptosis of the autonomic neuron in streptozotocin-induced diabetic rats, and observe the effect of intervention with nerve growth factor(NGF) on the apoptosis. Methods: A total of 29 male Sprague-Dawley rats were divided into three groups, i.e. normal control(NC, n = 12), untreated diabetic(DM, n = 9) and diabetic treated with NGF daily of 500 μg/kg for 30 days(DM+NGF, n = 8). The diabetic rat models were produced by intraperitoneal injection with streptozotocin(65 mg/kg). Over 3 months since the diabetes were setup, the superior cervical sympathetic ganglions(SCG) and the celiac ganglions(CG) were removed and fixed with 10% paraformaldchyde. Apoptosis was measured using terminal deoxynucleotidyl transferase-mediated dUTP nick-end labelling(TUNEL). Apoptotic index (AI) was calculated by computer image analysis system. Results: The AI of SCG and CG in DM and DM+NGF group were significant higher than those of NC group(P < 0.001) respectively. There was no difference of AI of SCG and CG between DM group and DM+NGF group (both P > 0.05). Conclusion: Neuron apoptosis may contribute to the pathophysiology of diabetic autonomic neuropathy and NGF can not prevent the apoptosis of autonomic neuron in diabetic rats. | Qinglin Lou Rongwen Bian Tao Peng Xiaojun Ouyang Hui Xia Liubao Gu Yongzhen Mo | 2006 | Journal of Nanjing Medical University2006，20，6： | 0 |
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