|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 乳汁免疫和猪流行性腹泻病毒病疫苗:历史和现状(译文)显示文摘由于肠道病毒感染导致仔猪在发病率、死亡率和生产能力丧失方面的影响,每年给养猪者带来数百万美元的损失。2013—2014年间,猪流行性腹泻病毒(PEDV)病的暴发给美国养猪业带来了9亿~18亿美元的经济损失。被动乳汁免疫被认为是保护新生哺乳仔猪免受PED等肠道疾病危害的最有希望和有效的方法。通过乳汁免疫被动保护哺乳仔猪的效果依赖于病原特异性IgA浆细胞转运至乳腺的数量和乳汁中分泌型IgA的积累程度,这种免疫途径被定义为'肠-乳腺-sIgA轴'。由于胎盘的不可穿透性,新生仔猪处于无免疫球蛋白的状态,对很多的传染性病原体极易感。它们仅依靠来源于母源的初乳和乳汁抗体获得被动保护。先前开发的关于猪传染性胃肠炎病毒(TGEV)病的活疫苗和灭活疫苗,提供了对母源性免疫和仔猪被动保护机制的理解。在这篇文章中,综述了猪传染性胃肠炎病毒诱导乳汁免疫的研究进展,并指出对当前养猪业正努力控制的猪流行性腹泻病毒感染和相关疫苗的研究方向。同时研究和鉴别出影响乳汁免疫和'肠-乳腺-sIgA轴'的各种因素,有助于改善妊娠母猪预防猪流行性腹泻病毒感染以及改进其它肠道病原用疫苗方案,从而达到提升整个猪群的免疫力、猪群健康和企业生产力的目的。 | Langel Stephanie N Paim Francine Chimelo Lager Kelly M Vlasova Anastasia N Saif Linda J 吕茂杰 | 2017 | 养猪2017，，1： | 3 |
| 2 | Influence of surveillance renal allograft biopsy on diagnosis and prognosis of polyomavirus-associated nephropathy显示文摘 | BUEHRIG C K LAGER D J STEGALL M D | 2003 | Kidney Int2003，64，2： | 1 |
| 3 | Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs显示文摘 | Solorzano A Webby R J Lager K M | 2005 | J Virol2005，79，： | 1 |
| 4 | Development ofreal-time polymerase chain reaction assays for rapid detection and differentiation of wild-type pseudorabies and gene- deleted vaccine viruses显示文摘 | Ma W Lager K M Richt J A | 2008 | Journal of Veterinary Diagnostic Investigation2008，20，4： | 1 |
| 5 | Eta-1 participates in and facilitates developmental expression of hypoxia-induced mitogenic factor n mouse lung 显示文摘 | Li B Lager J Wang D eta| | 2007 | Front Biosci2007，12，： | 1 |
| 6 | Refinement of the structures of Sr3Al2O6 and the hydrogarnet Sr3 Al2 (O4 D4 )3 by Rietveld analysis of neutron powder diffraction data 显示文摘 | Chakoumakos B C Lager G A Fernandez - Baca J A | 1992 | Acta Crystallographica C1992，48，： | 1 |
| 7 | Ets-1 Participates in and facilitates developmental expression of hypoxia-induced mitogenie factor in mouse lung显示文摘 | Li B Lager J Wang D | 2007 | Frony Biosci2007，12，： | 1 |
| 8 | Metanephric adenoma, nephrogenic rests, and Wilms tumor: a histologic and immunophenotypic comparison显示文摘 | Muir T E Cheville J C Lager D J | 2001 | Am J Surg Pathol2001，25，10： | 1 |
| 9 | Ethnic and gender differences in psychosocial factors ; glycemic control, and quality of life among adult type 2 diabetic patients显示文摘 | Misra R Lager J | 2009 | J Diabetes Complications2009，23，1： | 1 |
| 10 | Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs显示文摘 | Solorzano A Webby R J Lager K M | 2005 | J Virol2005，79，12： | 1 |
| 11 | Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays显示文摘 | TENENBAUM S A CARSON C C LAGER P J | 2000 | Proceedings of the National Academy of Sciences2000，97，14： | 1 |
| 12 | A current assessment of the relative role porcine parvovirus as a cause of fetal porcine death显示文摘 | Mengeling W L Lager K M Zimmerman J K | 1991 | J Vet Diagn Invest1991，3，： | 1 |
| 13 | In vivo growth of porcine reproductive and respiratory syndrome virus engineered nsp2 deletion mutants显示文摘 | FAABERG K S KEHRU M J LAGER KM | 2010 | Virus Res2010，154，12： | 1 |
| 14 | A current assessment of the role of porcine parvovirus as a cause of fetal porcine death显示文摘 | Mengeling W L Lager K M Zimmerman J K | 1991 | J Vet Diagn Invest1991，3，： | 1 |
| 15 | Leydig cell tumor of the testis: A clinicopathologic, DNA content, and MIB-1 comparison of nonmetastasizing and metastasizing tumors 显示文摘 | CheviUe JC Sebo T J Lager DJ Bostwick DG Farrow GM | 1998 | Am J Surg Pathol1998，22，： | 1 |
| 16 | Low salinity oil recovery-Anexperimental investigation显示文摘 | Lager A Webb K J Black C J | 2008 | Petrophysics2008，49，1： | 1 |
| 17 | Pharmacokinetics of enfloxacin in fingerling rainbow trout (Oncorhynchus mykiss)显示文摘 | Bowser P R Wooster G A St Lager J | 1992 | J Vet Pharmacol Therap1992，15，1： | 1 |
| 18 | A current assessment of the relative role porcine parvovirus as a cause of fetal porcine death显示文摘 | MENGELING W L LAGER K M ZIMMERMAN J K | 1991 | J Vet Diagn Invest1991，3，： | 1 |
| 19 | Response of the transcriptome of the intertidal red seaweed Chondrus crispus to controlled and natural stresses 显示文摘 | Collan J Guisle-Marsollier I Lager J J | 2007 | New Phytologist2007，176，1： | 1 |
| 20 | Real - time reverse tran- scription - polymerase chain reaction assays for the detection and differentiation of North American swine influenza viruses 显示文摘 | Rieht J A Lager K M Clouser D F | 2004 | J Vet Diagn Invest2004，16，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员