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334篇 您的检索式：作者名="Lakatta"

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	题名	作者	年代	出处	被引量
1	限制卡路里摄入可抑制大鼠促进动脉衰老的炎症反应,保持年轻的表型显示文摘老化呈指数性增加典型心血管病的发病率和死亡率,这主要是由于动脉壁内分子、细胞和组织水平的动脉促炎变化。动物实验中,大鼠的卡路里限制(calorie restriction,CR)改善了动脉功能并延长了健康跨度和寿命。然而,CR如何影响大鼠动脉壁内分子,细胞和组织表型促炎变化仍有待阐明。该文选取随意喂食的344只年轻(6个月大)和老(24个月大)的Fischer大鼠,获取主动脉;另外选取1组在1个月大时开始只维持40%CR。	刘青叶鹏 Wang MY Zhang L Zhu WQ Zhang J Kim SH Wang YS Ni L Telljohann R Monticone RE McGraw K Liu LJ Rafael de Cabo Lakatta EG	2018	中华高血压杂志2018，26，11：	3
2	人的衰老:心血管在结构与功能方面的改变显示文摘在衰老的过程中,心血管系统功能降低的速度因人而异,这提示多种因素调控“生物钟”,或遗传机理决定年龄对循环系统的影响。调节衰老的诸因素疾病发生影响衰老的一个因素是疾病的发生,对疾病和衰老必须详细描述,以便能够加以识别。当疾病的临床症状和体征明显时,识别并不困难;然而,隐匿性疾病虽可引起显著的功能损害,但可无症状表现。在研究年龄对人体心血管功能影响时,尤需慎重考虑,因冠状动脉粥样硬化的患病率随年龄增长显著增加,而且在老年人隐性较显性更常见。在老年人的尸检中,冠状动脉狭窄的百分比虽增高。	Lakatta E G 吕国良	1989	国外医学(老年医学分册)1989，，3：	2
3	Elevated Aortic Pulse Wave Velocity, a Marker of Arterial Stiffness, Predicts Cardiovascular Events in Well-Functioning Older Adults显示文摘	Kim Sutton-Tyrrell Samer S. Najjar Robert M. Boudreau Lakshmi Venkitachalam Varant Kupelian Eleanor M. Simonsick Richard Havlik Edward G Lakatta Harold Spurgeon Stephen Kritchevsky Marco Pahor Douglas Bauer Anne Newman	2005	Circulation2005，，25：	2
4	Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease 显示文摘	Lakatta EG Levy D	2003	Circulation2003，107，2：	1
5	A coupled system ofin - tracellular Ca2+ clocks and surface membrane voltageclocks controls the timekeeping mechanism of the heart’s pace-maker显示文摘	Lakatta EG Maltsev VA Vinogradova TM	2010	Circ Res2010，106，：	1
6	κandδopioid receptor stimulation affects cardiac myocyte function and Ca2+release from an intracellular pool in myocytes and neurons显示文摘	Spurgeon H Lakatta EG	1992	Circ Res1992，70，：	1
7	Arterial aging and subelinical arterial disease are fundamentally interwined at macroscopic and molecular levels显示文摘	Lakatta EG Wang M Najjar SS	2009	Med Clin North Am2009，93，3：	1
8	Arterial and cardiac aging:major shareholders in cardiovascular disease enterprises:Part I:aging arteries:a 'set up' for vascular disease显示文摘	Lakatta EG Levy D	2003	Circulation2003，107，1：	1
9	Arterial-ventricular coupling: mechanistic insights into cardiovascular performance at rest and during exercise显示文摘	Chantler PD Lakatta EG Najjar SS	2008	J Appl Physiol ( 1985 )2008，105，4：	1
10	Perspectives on mammalian cardiovascular aging: humans to molecules显示文摘	Lakatta EG Sollott SJ	2002	Comp Biochem Physiol A Mol Integr Physiol2002，132，4：	1
11	Role of muscle loss in the age-associated reduction in VO2max显示文摘	FLEG J L LAKATTA E G	1988	J Appl Physiol1988，65，3：	1
12	Cyclic variation of intracellular calcium: a critical factor for cardiac pacemaker cell dominance 显示文摘	Lakatta EG Maltsev VA Bogdanov KY	2003	Circ Res2003，92，3：	1
13	A coupled SYSTEM of intracellular Ca^2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker 显示文摘	LAKATTA E G MALTSEV V A VINOGRADOVA T M	2010	Circ Res2010，106，4：	1
14	Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises part Ⅰ: aging arteries: a 'set up' for vascular disease 显示文摘	Lakatta EG Levy D	2003	Circulation2003，107，1：	1
15	Arterial and cardiac aging major share-holders is in cardiovascular disease enterprises Part II the agingheart in health links to heart disease显示文摘	Lakatta EG Levy D	2003	Circulation2003，107，10：	1
16	A coupled sys- tem of intraeellular Ca^2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pace- maker显示文摘	Lakatta E G Maltsev V A Vinogradova T M	2010	CircRes2010，106，4：	1
17	Arterial-ventricular coupling with aging and disease显示文摘	Chantler PD Lakatta EG	2012	Front Physiol2012，3，：	1
18	Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part Ⅲ:cellular and molecular clues to heart and arterial aging 显示文摘	Lakatta EG	2003	Circulation2003，107，3：	1
19	Direct measurement of SR release flux by tracking Ga2+ spikes' in rat cardiac myocytes显示文摘	Song LS Sham JS Stem MD Lakatta EG Cheag H		0，，3：	1
20	Normal heart rhythm is initiated and regulated by an intracellular calcium clock within pacemaker cells显示文摘	Maltsev VA Lakatta EG	2007	Heart Lung Circ2007，16，5：	1

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