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18篇 您的检索式：作者名="Lake Andrew"

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		题名	作者	年代	出处	被引量
	1	Requirement of Pygopus 2 in breast cancer显示文摘	Phillip Andrews Blue Lake Catherine Popadiuk Kenneth Kao	2007	International Journal of Oncology2007，，2：	2
	2	Requirement of pygopus 2 in breast cancer 显示文摘	Andrews PG Lake BB Popadiuk C	2007	Int J Oncol2007，30，2：	1
	3	显示文摘	WU Guo-feng JAN de LEEUW ANDREW K SKIDMORE Will the Three Gorges Dam affect the underwater light climate ofVallisneris spiralis L and food habitat of Siberian crane in Poyang Lake	2009	Hydrobiologia2009，623，：	1
	4	Requirement of pygopus 2 in breast cancer显示文摘	Andrews P G Lake B B Popadiuk C Kao K R	2007	Int J Oncol2007，30，：	1
	5	Requirement of Pygopus 2 in breast cane er 显示文摘	Andrews PG Lake BB Popadiuk C	2007	Int J Oneo12007，30，2：	1
	6	Requirement of Pygopus 2 in breast cancer显示文摘	Andrews P G Lake B B Popadiuk C	2007	Int J Oncol2007，30，2：	1
	7	Evaluation of low-temperature properties of HMA mixtures 显示文摘	Peter E Sebaaly Andrew Lake Jon Epps	2002	J Trans Eng2002，128，6：	1
	8	Requirement of Pygopus 2 in breast cancer显示文摘	Andrews PG Lake BB Popadiuk C	2007	IntJ Oncol2007，30，2：	1
	9	Evaluation of Low-Temperature Properties of HMA Mixtures显示文摘	Peter E Sebaaly Andrew Lake Jon Epps	2002	J Transp Engrg2002，128，6：	1
	10	Requirement of Pygopus 2 in breast cancer显示文摘	Andrews PG Lake BB Popadiuk C	2007	Int J Oncol2007，30，2：	1
	11	Evaluation of low-temperature properties of HMA mixtures 显示文摘	Sebaaly Peter E Lake Andrew Epps Jon	2002	Journal of Transportion Engineering2002，128，6：	1
	12	Requirement of Pygopus 2 in breast cancer 显示文摘	Andrews PG Lake BB Popadiuk C	2007	Int J Oncol2007，30，2：	1
	13	Evaluation of low- temperature properties of HMA mixtures 显示文摘	Sebaaly Peter E Lake Andrew Epps Jon	2002	Journal of Transportion Engineering2002，128，6：	1
	14	LowMolecular Weight Fucoidan Increases VEGF165 -induced En-dothelial Cell Migration by Enhancing VEGF165 Binding to VEG-FR-2 and NRP1 J 显示文摘	Andrew C Lake Roger Vassy Melanie Di Benedetto	2006	Biol Chem2006，281，37：	1
	15	Requirement of Pygopus 2 in breast cancer显示文摘	Andrews PG Lake BB Popadiuk C	2007	Int J Oncol2007，30，2：	1
	16	腹部X线片对于重症监护病房的胃肠道出血患者无益	Andrews A.H Lake J.M Shorr A.F 程欣	2005	世界核心医学期刊文摘(胃肠病学分册)2005，0，8：	0
	17	绳结花园显示文摘Ruy Klein建筑事务所综合建筑,自然和技术,思考当代设计的问题。20世纪引人瞩目的技术变革开拓出了材料在人工和自然间具有模糊边界的奇特领域。	Andrew Lucia Andrew Ruggles Matthew Lake Megan Born Aaron Jessi	2010	城市环境设计2010，，10：	0
	18	FOXP3 protects conventional human T cells from premature restimulation-induced cell death显示文摘The adaptive immune response relies on specific apoptotic programs to maintain homeostasis.Conventional effector T cell(Tcon)expansion is constrained by both forkhead box P3(FOXP3)^(+)-regulatory T cells(Tregs)and restimulation-induced cell death(RICD),a proprlocidal apoptosis pathway triggered by repeated stimulation through the T-cell receptor(TCR).Constitutive FOXP3 expression protects Tregs from RICD by suppressing SLAM-associated protein(SAP),a key adaptor protein that amplifies TCR signaling strength.The role of transient FOXP3 induction in activated human CD4 and CD8 Tcons remains unresolved,but its expression is inversely correlated with acquired RICD sensitivity.Here,we describe a novel role for FOXP3 In protecting human Tcons from premature RICD during expansion.Unlike FOXP3-mediated protection from RICD in Tregs,FOXP3 protects Tcons through a distinct mechanism requiring de novo transcription that does not require SAP suppression.Transcriptome profiling and functional analyses of expanding Tcons revealed that FOXP3 enhances expression of the SLAM family receptor CD48,which in turn sustains basal autophagy and suppresses pro-apoptotic p53 signaling.Both CD48 and FOXP3 expression reduced p53 accumulation upon TCR restimulation.Furthermore,silencing FOXP3 expression or blocking CD48 decreased the mitochondrial membrane potential in expanding Tcons with a concomitant reduction in basal autophagy.Our findings suggest that FOXP3 governs a distinct transcriptional program in early-stage effector Tcons that maintains RICD resistance via CD48-dependent protective autophagy and p53 suppression.	Kelsey Voss Camille Lake Christopher R.Luthers Nathaniel M.Lott Batsukh Dorjbal Swadhinya Arjunaraja Bradly M.Bauman Anthony R.Soltis Gauthaman Sukumar Clifton LDalgard Andrew L.Snow	2021	Cellular & Molecular Immunology2021，18，1：	0

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