|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 2018加拿大心境障碍与焦虑障碍治疗协作组/国际双相障碍学会指南:双相障碍的管理显示文摘加拿大心境障碍与焦虑障碍治疗协作组(Canadian Network for Mood and Anxiety Treatments,CANMAT)曾于2005年发布了第1版双相障碍管理指南,并分别于2007、2009和2013年对该指南进行了更新,其中最近的2次更新是与国际双相障碍学会(International Society for Bipolar Disorders,ISBD)合作完成。2018版CANMAT/ISBD双相障碍治疗指南(以下简称指南)反映了自2005年首版指南发表以来本领域取得的重大进展,包括疾病诊断与疾病管理的更新以及药物治疗与心理治疗的近期研究进展。这些前沿进展中综合考虑了循证证据的级别,并基于治疗疗效、临床实践经验、安全性、耐受性和药物导致的转相风险等,对一线、二线及三线治疗方案进行了简明而清晰的推荐。本指南中新增内容涵盖了双相Ⅰ型障碍(BD-Ⅰ)的躁狂发作急性期、抑郁发作急性期和双相障碍维持期的一线及二线治疗推荐等级划分。这种对治疗推荐等级的划分综合考虑了治疗方法对双相障碍不同时相的影响,将进一步帮助临床医生做出基于循证证据的治疗决策。锂盐、喹硫平、双丙戊酸盐、阿塞那平、阿立哌唑、帕利哌酮、利培酮和卡利拉嗪单药或联合使用被推荐为躁狂发作急性期的一线治疗选择。BD-Ⅰ抑郁期的一线治疗选择包括喹硫平、鲁拉西酮、锂盐、拉莫三嗪单药,鲁拉西酮联合锂盐或双丙戊酸盐或拉莫三嗪辅助治疗。尽管急性期治疗有效的药物通常应继续用于BD-Ⅰ的维持期治疗,但也存在一些特殊情况(例如抗抑郁药)。现有数据表明,锂盐、喹硫平、双丙戊酸盐、拉莫三嗪、阿塞那平和阿立哌唑单药或联合治疗应被视为维持治疗的初始或更换治疗方案时的一线选择。除了探讨BD-Ⅰ的相关问题外,本指南中还对双相Ⅱ型障碍(BD-Ⅱ)的临床管理进行了系统回顾并给予治疗推荐,同时针对特殊人群也有相关推荐,如处于各个生殖周期的女性、儿童、青少年和老年人。此外,本指南中还讨论了特定精神疾病及共病(如物质滥用、焦虑障碍和代谢性疾病)的影响。最后,本指南中概述了安全性和药物监测的相关问题。CANMAT/ISBD工作组希望本指南能够成为全球临床医生的实用工具。 | Lakshmi N Yatham Sidney H Kennedy Sagar V Parikh Ayal Sehaffer David J Bond Benicio N Frey Verinder Sharma Benjamin I Goldstein Soham Rej Serge Beaulieu Martin Alda Glenda MaeQueen Roumen V Milev Arun Ravindran Claire O'Donovan Diane Mclntosh Raymond W Lam Gustavo Vazquez Flavio Kapczinski Roger S Melntyre Jan Kozicky Shigenobu Kanba Beny Lafer Trisha Suppes Joseph R Calabrese Eduard Vieta Gin Malhi Robert M Post Michael Berk 胡晨(译) 王刚(译) | 2019 | 中华精神科杂志2019，52，1： | 25 |
| 2 | Numerical prediction experiment on Typhoon Maggie (9903)显示文摘The movement of Typhoon Maggie (9903) in June 1999 is one of the rare cases ever seen in the history. At 00U on June 6 Maggie was located at about 70 km to the southwest of Taiwan. When it arrived at the coastal region of Shanwei City (22.8N, 116.5E), it turned suddenly to move southwestward along the southern China coastal line. De June 7 Maggie finally turned to move northward, making landfall to the north of Shangchuan Island. The experimental numerical prediction system on typhoon movement that was designed based on MM5 is proved quite successful for the 48h prediction of Maggie’s movement and rainfall. The mean prediction error of typhoon track is 81 km for 0-24 h and 74 km for 24-48 h. The location of typhoon center in the initial field of the model is approximately 100 km away from the actual observations. In order to modify the location of typhoon center, a bogus typhoon was intro- duced into the model and the prediction of typhoon track was improved in 0-24 h time interval. But the prediction error was enlarged in 24-36 h. We also performed a sensitivity experiment of changing the land of southern China into the ocean. It is found that the orientation of South China coastal line and the topography have no obvious effect on the movement of Typhoon Maggie. | Fong Soi Kun, Wu Chisheng, Hao I Pan, Lam Kin Hang Ku Chi Meng, Wang Anyu, Lin Wenshi (1. Macao Meteorological and Geophysical Bureau, Macao, China 2. Department of Atmospheric Sciences, Zhongshan University, Guangzhou 510275, China) | 2001 | Acta Oceanologica Sinica2001，20，2： | 3 |
| 3 | Drug the rapy for small-cell lung cancer(SCLC)-new molecular strategies fol the rapy显示文摘 | Bruck I W M Lam pert S | 2008 | Pneum oiogie2008，62，1： | 1 |
| 4 | Preferred risk allocation in target cost contracts in con- struction显示文摘 | Joseph H L Chan Daniel W M Chan Patrick T I Lam | 2011 | Facilities2011，29，1314： | 1 |
| 5 | Prevalence of dementia in Chinese elderly in Hong Kong显示文摘 | Chiu HFK Lam LCW Chi I | 1998 | Neurology1998，50，： | 1 |
| 6 | Flame propagation through layered fuel-air mixtures显示文摘 | Feng C C Lam S H Glassman I | 1975 | Combustion Scienee and Technology1975，，10： | 1 |
| 7 | A decision support system for environmental effects monitoring显示文摘 | Booty W G Wong I Lam D | | Environment Model- ling Software0，24，： | 1 |
| 8 | Constant normal stiffness direct shear testing for socketed pile design in weak rock显示文摘 | JONSTON I W LAM T S K WILLIAMS A F | 1987 | Geotechnique1987，37，1： | 1 |
| 9 | Simulation of Heat Transfer and Cure in Pultrusion with a General-Purpose Finite Element Package显示文摘 | CROUCH I G LAM Y C | 2000 | Composites Science and Technology2000，60，6： | 1 |
| 10 | Three-dimensional ultrasound features of the polycystic ovary and the effect of different phenotypic expressions on these parameters显示文摘 | LAM P M JOHNSON I R RAINE-FENNING N J | 2007 | Hum Reprod2007，22，12： | 1 |
| 11 | A community study of sleep disordered breathing in middle-aged Chinese men in Hong Kong 显示文摘 | Ip M S Lam B Lauder I J etal | 2001 | Chest2001，119，1： | 1 |
| 12 | Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial显示文摘 | Chu T Benzie I Lam C | 2012 | British journal of Nutrition2012，107，7： | 1 |
| 13 | Prevalence of pH - documented laryngopharyngeal reflux in Chinese patients with clinically suspec- ted reflux laryngitis显示文摘 | LAM P WEI W I HUI Y | 2006 | Am J Otolaryngol2006，27，3： | 1 |
| 14 | Variability of the hepatotoxin microcystin - LR in hypereutrophic drinking water lakes显示文摘 | KOTAK B G LAM A K I PREPAS E E | 1995 | J Phycol1995，3，： | 1 |
| 15 | Nanosized bioceramic particles could function as efficient gene delivery vehicles with target specificity for the spleen显示文摘 | TAN K CHEANG P HO I A W LAM P Y P HUI K M | 2007 | Gene Therapy2007，14，： | 1 |
| 16 | Right ventricular stunning in inferior myocardial infarction显示文摘 | Ramzy'I S O'Sullivan C A Lam Y Y | 2009 | Int J Cardiol2009，136，3： | 1 |
| 17 | Molecular damage in the bronchial epithelium of current and former smokers显示文摘 | Wistuba I I Lam S Behrens C | 1997 | J Natl Cancer Inst1997，89，： | 1 |
| 18 | Community Attitudes towards Living Arrangements between the Elder and their Adult Children in Hong Kong显示文摘 | Lam T-p Chi I Piterman L Lam C Lauder I | 1998 | Journal of Cross-Cultural Gerontology1998，，13： | 1 |
| 19 | Bulk-quantity Si nanowires synthesized by SiO sublimation 显示文摘 | Zhang Y F Tang Y H Lam C Wang N Lee C S Bello I Lee S T | 2000 | Journal of Crystal Growth2000，212，2： | 1 |
| 20 | Mesenchymal stem cells inhibit proliferation and apoptosis of tumor cells: impact on in vivo tumor growth 显示文摘 | Ramasamy R Lam EW Soeiro I | 2007 | Leukemia2007，21，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员