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| 1 | Testicular sperm extraction and intracytoplasmic sperm injection in non obstructive azoospermia显示文摘Objective To report the experience in sperm extraction from testicular biopsies (TESE) performed from March 1996 to July 1998 in men with non obstructive azoospermia (NOA) Methods Comparisons of age, volume of both testes, serum FSH and testosterone in men, and histology of testicular samples in the first cycles between cycles with spermatozoa found and those without spermatozoa found were performed Comparisons of fertilization, cleavage and pregnancy rates between cycles with spermatozoa injected and those with spermatids injected were performed Results Spermatozoa were found in only 12 out of 26 first TESE cycles (46 2%) and other cycles had spermatids (round cells) only Age of men, history of mumps orchitis/oligozoospermia, volume of both testes and serum FSH/testosterone levels in men were not significantly different between cycles with and without spermatozoa The fertilization rate was significantly higher in cycles with spermatozoa injected than those with round cell injections (63 3% vs 23 2%, P <0 0001, Chi squared test) The pregnancy rate was 14 3% per cycle when spermatozoa were injected Conclusions TESE followed by Intracytoplasmic sperm injection (ICSI) is an effective treatment in patients with NOA Less than half of the patients undergoing TESE had spermatozoa recovered Age of men, volume of both testes and serum FSH/ testosterone levels in men were not useful in predicting successful recovery Compared to using ejaculated and epididymal spermatozoa, fertilization and pregnancy rates were achieved when testicular spermatozoa were used for | Ng Hung Yu Ernest, Lau Yee Lan, Yeung Shu Biu, So Wai Ki, Tam Po Chor and Ho Pak Chung | 2000 | Chinese Medical Journal2000，，3： | 7 |
| 2 | A Subpopulation of CD26 + Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer显示文摘 | Roberta Pang Wai Lun Law Andrew C.Y. Chu Jensen T. Poon Colin S.C. Lam Ariel K.M. Chow Lui Ng Leonard W.H. Cheung Xiao R. Lan Hui Y. Lan Victoria P.Y. Tan Thomas C. Yau Ronnie T. Poon Benjamin C.Y. Wong | 2010 | Cell Stem Cell2010，，6： | 4 |
| 3 | Hydrocarbon Systems in the North-Eastern Area of the Song Hong Basin显示文摘 | Trinh Xuan Cuong Phan Ngoc Trung Tong Duy Cuong Nguyen Bich Ha Phung Lan Phtro'ng Hoang ThiLan Nguyen Hoang Son | 2013 | Journal of Earth Science and Engineering2013，3，12： | 3 |
| 4 | Theoretical basis of a beneficial role for vitamin D in viral hepatitis显示文摘Abnormal bone metabolism and dysfunction of the calcium-parathyroid hormone-vitamin D axis have been reported in patients with viral hepatitis. Some studies suggested a relationship between vitamin D and viral hepatitis. Genetic studies have provided an opportunity to identify the proteins that link vitamin D to the pathology of viral hepatitis (i.e., the major histocompatibility complex class Ⅱ molecules, the vitamin D receptor, cytochrome P 450 , the renin-angiotensin system, apolipoprotein E, liver X receptor, toll-like receptor, and the proteins regulated by the Sp1 promoter gene). Vitamin D also exerts its effects on viral hepatitis via non-genomic factors, i.e., matrix metalloproteinase, endothelial vascular growth factor, prostaglandins, cyclooxygenase-2, and oxidative stress. In conclusion, vitamin D could have a beneficial role in viral hepatitis. Calcitriol is best used for viral hepatitis because it is the active form of the vitamin D 3 metabolite. | Khanh vinh quoc Luong Lan Thi Hoàng Nguyen | 2012 | World Journal of Gastroenterology2012，18，38： | 3 |
| 5 | Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant显示文摘Dear Editor,Most recently,a new SARS-CoV-2 variant of concern(VOC)Z Omicron(B.1.1.529),was first reported to the World Health Organization(WHO)from South Africa and then quickly spread to many countries,1,2 posing a serious threat to current vaccine prevention and antibody therapeutic strategies.Several studies have reported that the Omicron variant successfully escapes from neutralizing antibodies elicited by COVID-19 vaccines or from COVID-19 convalescent patients. | Shuai Xia Jasper Fuk-Woo Chan Lijue Wang Fanke Jiao Kenn Ka-Heng Chik Hin Chu Qiaoshuai Lan Wei Xu Qian Wang Chao Wang Kwok-Yu ng Yuen Lu Lu Shibo Jiang | 2022 | Cell Research2022，32，4： | 2 |
| 6 | Macrophage apoptosis in rat crescentic glomerulonephritis显示文摘 | Lan HY Mitsuhashi H Ng YY | 1997 | Am J Pathol1997，151，2： | 1 |
| 7 | A rapid decline in serum estradiol concentrations around the mid - luteal phase had no adverse effect on outcome in 763 assisted reproduction cycles 显示文摘 | Hung Yu Ng E Shu Biu Yeung W Yee Lan Lau E | 2000 | Hum Reprod2000，15，9： | 1 |
| 8 | Association of Human-Leukocyte-Antigen Class I (B * 0703) and Class II(DRB1 * 0301) Genotypes with Suscepti- bility and Resistance to the Development of Severe Acute Respiratory Syn- drome显示文摘 | Ng M H Lan K M Li L et a/ | 2004 | Infect Dis2004，190，3： | 1 |
| 9 | Incomplete ablation after radiofrequency ablation of hepatocellular carcinoma:analysis of risk factors and prognostic factor显示文摘 | Lan VW Ng KK Chok KS | | 0，，03： | 1 |
| 10 | Optimization of a piezoelectric ceramic actuator显示文摘 | Jiang T Y Ng T Y Lan K Y | 2001 | Sensors and Actuators2001，84，： | 1 |
| 11 | High serum oestradiol concentrations in fresh IVF cycles do not impair implantation and pregnancy rates in subsequent frozen-thawed embryo transfer cycles显示文摘 | Yu Ng EH Yeung WS Yee Lan Lau E | 2000 | Hum Reprod2000，15，2： | 1 |
| 12 | Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats显示文摘 | Lan HY Ng YY Huang TP | 1998 | Kidney Int1998，54，3： | 1 |
| 13 | Stable and optimal anticoagulation is achieved with asingle dose of intravenous enoxaparin in patients undergoing percutaneouscoronary intervention显示文摘 | Chen WH Lan CP Lan NG | 2002 | J Invasive Cardiol2002，14，8： | 1 |
| 14 | High serum oestradiol concentrations in fresh IVF cycles do not impair implantation and pregnancy rates in subsequent frozen-thawed embryo transfer cycles显示文摘 | YU NG E H YEUNG W S YEE LAN LAU E | 2000 | Hum Reprod2000，15，2： | 1 |
| 15 | High serumoes tradiol concentrations infresh IVF cyclesdonot impair implantation and prgnancy rates in subsequent frozenthawed embryotransfer cycles Hum显示文摘 | Ernest Hung Yu Ng William Shu Biu Yeung Estella Yee Lan Lau | 2000 | Reprod2000，15，5： | 1 |
| 16 | High serum oestradiol concentrations in fresh IVF cycles od not impair implantation and pregnancy rates in subsequent frozen-thawed embryo transfer cycles显示文摘 | Yu Ng EH Yeung WS Yee Lan Lau E | 2000 | Hum Reprod2000，15，2： | 1 |
| 17 | A rapid de-cline in serum oestradiol concentrations around the midluteal phasehad no adverse effect on outcome in 763 assisted reproduction cy-cles 显示文摘 | Hung Yu Ng E Shu Biu Yeung W Yee Lan Lan E | 2000 | Hum Reprod2000，15，9： | 1 |
| 18 | High serum oestradiol concentrations in fresh IVF cycles do not impair implantation and pregnancy rates in subsequent frozen-thawed embryo transfer cycles显示文摘 | Yu Ng EH Yeung WS Yee Lan Lau E | | 0，，02： | 1 |
| 19 | A simple,reliable,and sensitivemethod for nonradioactive in situ hybridization:use of microwaveheating to improve hybridization efficiency and preserve tissue mor-phology显示文摘 | Lan H Y Mu W NG Y Y | 1996 | J Histochem Cytochem1996，44，3： | 1 |
| 20 | Anti-AIDS Age nts-X X VI,structure-activiy correlat ions of gomisin-Grelates anti HIV lig naris from Kadsura interior and of re lates syntheticanaiogs显示文摘 | CHEN DAOFENG ZHANG SHUNXI NG XIE LAN | 1997 | Bioorg Med C hem1997，5，8： | 1 |
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