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| 1 | Low hypoxia inducible factor-1α(HIF-1α)expression in testicular germ cell tumors--a major reason for enhanced chemosensitivity?显示文摘The molecular basis for enhanced chemosensitivity of testicular germ cell tumors(GCT)has been an area of great interest,as it could potentially give us therapeutic leads in other resistant malignancies.Thus far,however,the increased sensitivity of GCT has been variously attributed to multiple factors—an inability to detoxify cisplatin,a lack of export pumps,an inability to repair the DNA damage,an intact apoptotic cascade and lack of p53 mutation;but a unifying underlying etiology leading to the aforementioned processes and having a translational implication has so far been elusive.Herein,we offer evidence to support a potential significant role for the previously demonstrated low hypoxia inducible factor-1α(HIF-1α)expression in mediating the general exquisite chemosensitivity of testicular GCT,through the aforementioned processes.This molecular mechanism based hypothesis could have a significant translational implication in platinum refractory GCT as well as other platinum resistant malignancies. | niraj shenoy roxana dronca fernando quevedo stephen a boorjian john cheville brian costello manish kohli thomas witzig lance pagliaro | 2017 | Chinese Journal of Cancer Research2017，29，4： | 4 |
| 2 | Recognizes veterinary shortage in public health 显示文摘 | JESSUP D A KARESH W B LANCE W R | 2005 | J Am Vet bled Assoc2005，227，3： | 1 |
| 3 | linoleic acid oxidation and transfer into milk in stunted lactating women with contrasting body mass indexes显示文摘 | Villalpando S Del Prado M Lance A | 2001 | Am J Clin Nutr2001，74，6： | 1 |
| 4 | Static and dy- namic shoulder stabilizer adaptations in javelin throwers: A preliminary study显示文摘 | EDOUARD P DAMOTTE A LANCE G | 2013 | Isok Exe Sci2013，21，1： | 1 |
| 5 | Slope stability analysis by finite elements显示文摘 | Griffiths D V Lanc P A | | 0，，03： | 1 |
| 6 | Effects of simulated acidic rain on yields of field- grown crops 显示文摘 | Lance S E Keith F L Elizabeth A C | 1982 | New Phytologist1982，91，： | 1 |
| 7 | One size does not fit all: The emerging frontier in large-scale marine conservation显示文摘 | Robert J. Toonen T. ‘Aulani Wilhelm Sara M. Maxwell Daniel Wagner Brian W. Bowen Charles R.C. Sheppard Sue M. Taei Tukabu Teroroko Russell Moffitt Carlos F. Gaymer Lance Morgan Nai‘a Lewis Anne L.S. Sheppard John Parks Alan M. Friedlander | 2013 | Marine Pollution Bulletin . 2013 (1-2)2013，，1： | 1 |
| 8 | Fixation failure in femoral neck fractures显示文摘 | Lance S Estrada David A Volgas James P Stannard | 2002 | Clinical Orthopaedics and Related Research2002，399，： | 1 |
| 9 | Fixation failure in femoral neck fractures显示文摘 | Lance S Estrada David A | 2002 | Iainical orthopaedics and related research2002，399，： | 1 |
| 10 | Variation inplasma lipids during the reproductive cycle of male and femaledesert tortoises,Gopherus agassizii 显示文摘 | LANCE V A PLACE A R GRUMBLES J S | 2002 | Journal of ExperimentalZoology2002，293，7： | 1 |
| 11 | Characterization of commercial EB-PVD TBC systems with CVD(Ni,Pt) Al bond coatings显示文摘 | HAYNES J A LANCE M J PINT B A WRIGHT I G | 2001 | Surface and Coatings Technology2001，，： | 1 |
| 12 | β-glu- can content and viscosity of extracts from waxy barley 显示文摘 | Ullrich S E Clancy J A Eslick R F Lance R C M | 1986 | Journal of Cereal Science1986，，4： | 1 |
| 13 | 3-165 MHz CMOS PLL Frequency Synthesizer for 3 V/5 V Operation显示文摘 | Yang HQward C Lee Lance K and Co Ramon S A Low Jitter 0 | 1997 | IEEE Solid-State Circuits1997，32，4： | 1 |
| 14 | TEMORA 1: a new zircon standard for Phanerozoic U-Pb geochronology显示文摘 | Lance P B Sandra L K Charlotte M A | 2003 | Chemical Geology2003，200，： | 1 |
| 15 | Sperm storage in the oviduct of the American alligator 显示文摘 | Gist D H Bagwill A Lance V | 2008 | J Exp Zool Part Ecol Genet Physiol2008，309，10： | 1 |
| 16 | Fixation failure in femoral neck fractures 显示文摘 | Lance S Estrada David A | 2002 | Clin Orthop2002，21，399： | 1 |
| 17 | Adult prostate sarcoma:The anderson cancer center experience显示文摘 | Sexton W J Lance R E Reyes A O | 2001 | J Urol2001，166，： | 1 |
| 18 | Efficacy of multifunnel traps for capturing Emeral ash borer (Coleoptera:Buprestidae): Effect of Color, Glue,and Other Trap Coatings 显示文摘 | Francese J A Fraser I Lance D R | 2011 | Journal Of Economic Entomology2011，104，3： | 1 |
| 19 | Optical properties metal nanoparticles and nano particle aggregates important in biosensors显示文摘 | Lazarides A A Lance Kelly K Jensen T R | 2000 | Journal of Molecular Structure2000，529，： | 1 |
| 20 | Thomas goetzen electrophilic tetraal-kylammonium nitrate nitration显示文摘 | SCOTT A SHACKELFORD MARK B ANDERSON LANCE C CHRISTIE | 2003 | Org Chem2003，68，2： | 1 |
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