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| 1 | Orthotopic liver transplantation for giant liver haemangioma: A case report显示文摘In liver haemangiomas, the risk of complication rises with increasing size, and treatment can be obligatory. Here we present a case of a 46-year-old female who suffered from a giant haemangioma causing severe portal hypertension and vena cava compression, leading to therapy refractory ascites, hyponatremia and venostasis-associated thrombosis with pulmonary embolism. The patients did not experience tumour rupture or consumptive coagulopathy. Surgical resection was impossible because of steatosis of the non-affected liver. Orthotopic liver transplantation was identified as the only treatment option. The patient's renal function remained stable even though progressive morbidity and organ allocation were improbable according to the patient's lab model for end-stage liver disease(lab MELD) score. Therefore, non-standard exception status was approved by the European organ allocation network 'Eurotransplant'. The patient underwent successful orthotopic liver transplantation 16 mo after admission to our centre. Our case report indicates the underrepresentation of morbidity associated with refractory ascites in the lab MELD-based transplant allocation system, and it indicates the necessity of promptly applying for non-standard exception status to enable transplantation in patients with a severe clinical condition but low lab MELD score. Our case highlights the fact that liver transplantation should be considered early in patients with non-resectable, symptomatic benign liver tumours. | Undine G Lange Julian N Bucher Markus B Schoenberg Christian Benzing Moritz Schmelzle Tanja Gradistanac Steffen Strocka Hans-Michael Hau Michael Bartels | 2015 | World Journal of Transplantation2015，5，4： | 6 |
| 2 | 早发急性心肌梗死的长期结局和风险评估:10年随访研究显示文摘早发急性心肌梗死(acute myocardial infarction,AMI)是一种罕见的疾病,发病率和死亡率很高。该文在再灌注治疗广泛应用的大环境下,纳入前瞻性研究人群进行早发AMI的预后研究。方法:这项前瞻性多中心研究中连续纳入102例AMI存活者(≤40岁),临床预后通过奥地利死亡登记处和维也纳集中患者管理系统进行查询。 | 刘莉 叶鹏 Winter MP Blessberger H Alimohammadi A Pavo N Huber K Wojta J Lang IM Wiesbauer F Goliasch G | 2017 | 中华高血压杂志2017，25，4： | 5 |
| 3 | Achalasia: will genetic studies provide insights?显示文摘 | Henning R. Gockel Johannes Schumacher Ines Gockel Hauke Lang Thomas Haaf Markus M. N?then | 2010 | Human Genetics2010，，4： | 3 |
| 4 | Gastroesophageal reflux disease after diagnostic endoscopy in the clinical setting显示文摘AIM: To investigate the outcome of patients with symptoms of gastroesophageal reflux disease (GERD) referred for endoscopy at 2 and 6 mo post endoscopy. METHODS: Consecutive patients referred for upper endoscopy for assessment of GERD symptoms at two large metropolitan hospitals were invited to participate in a 6-mo non-interventional (observational) study.The two institutions are situated in geographically and socially disparate areas. Data collection was by selfcompletion of questionnaires including the patient assessment of upper gastrointestinal disorders symptoms severity and from hospital records. Endoscopic finding using the Los-Angeles classification, symptom severity and it's clinically relevant improvement as change of at least 25%, therapy and socio-demographic factors were assessed. RESULTS: Baseline data were available for 266 patients and 2-mo and 6-mo follow-up data for 128 and 108 patients respectively. At baseline, 128 patients had erosive and 138 non-erosive reflux disease. Allmost all patient had proton pump inhibitor (PPI) therapy in the past. Overall, patients with non-erosive GERD at the index endoscopy had significantly more severe symptoms as compared to patients with erosive or even complicated GERD while there was no difference with regard to medication. After 2 and 6 mo there was a small, but statistically significant improvement in symptom severity (7.02 ± 5.5 vs 5.9 ± 5.4 and 5.5 ± 5.4 respectively); however, the majority of patients continued to have symptoms (i.e. , after 6 mo 81% with GERD symptoms). Advantaged socioeconomic status as well as being unemployed was associated with greater improvement. CONCLUSION: The majority of GORD patients receive PPI therapy before being referred for endoscopy even though many have symptoms that do not sufficiently respond to PPI therapy. | Nora B Zschau Jane M Andrews Richard H Holloway Mark N Schoeman Kylie Lange William CE Tam Gerald J Holtmann | 2013 | World Journal of Gastroenterology2013，19，16： | 2 |
| 5 | CD133,a novel marker for human prostatic epithelial stem cells显示文摘 | Richardson G D Robson C N Lang S H Neal D E Maitland N J Collins A T | 2004 | J Cell Sci2004，117，16： | 1 |
| 6 | Continuous intra-and postoperative thoracic epidural analgesia attenuates brain natriuretic peptide release after major abdominal surgery显示文摘 | SUTTNER S LANG K PIPER S N | 2005 | Anesth Analg2005，101，3： | 1 |
| 7 | Up-regulation of a cysteine protease accompanies the ethylene-insensitive senescence of daylily (Hemerocallis) flowers显示文摘 | Valpuesta V Lange N E Guerrero C | 1995 | Plant Molecular Biology1995，28，： | 1 |
| 8 | Application of flowcytometry and fluorescent in situ hybridization for assessment of exposures to airborne bacteria显示文摘 | Lange J L Thorne P S Lyncjh N 2001 | 2001 | Applied and Environmental Microbiology2001，63，4： | 1 |
| 9 | Hyperfractionated Cyclophosphamide in Combination with Pulsed Dexamethasone and Thalidomide(HyperCDT) in Primary Refractory or Relapsed Multiple Myeloma显示文摘 | Kropff M H Lang N Bisping G | 2003 | Br J Haematol2003，122，： | 1 |
| 10 | Effective-medium theory of chemical binding: Application to chemisorption显示文摘 | Norskov J K Lang N D | 1980 | Phys Rev B1980，21，： | 1 |
| 11 | Multitarget tracking using probability hypothesis density smoothing 显示文摘 | Nadarajah N Kirubarajan T Lang T | 2011 | IEEE Transactions on Aerospace and Electronic Systems2011，47，4： | 1 |
| 12 | miR-137 targets Cdc42 expression,in- duces cell cycle G1 arrest and inhibits invasion in colorectal cancer cells显示文摘 | Liu M Lang N Qiu M | 2011 | Int J Cancer2011，128，6： | 1 |
| 13 | Epidemiologieal survey of ossi- fication of the ligamentum flavum in thoraeic spine: CT imaging observation of 993 eases显示文摘 | Lang N Yuan HS Wang HL | 2013 | Eur Spine J2013，22，4： | 1 |
| 14 | Attachment formation following replantation of cultured cells into periodontal defects-a study in minipigs 显示文摘 | Lang H Schiller N Nolden R | 1998 | J Dent Res1998，77，2： | 1 |
| 15 | Obesity in pregnancy:a study of the impact of maternal obesity on NHS maternity services显示文摘 | Heslehurst N Lang R Rankin J | 2007 | BJOG2007，114，3： | 1 |
| 16 | Development and characterization of a Triticum aestivum-Haynaldia villosa translocation line T4VS·4DL conferring resistance to wheat spindle streak mosaic virus显示文摘 | ZHANG Q P LI Q WANG X WANG H Y LANG S P WANG Y N WANG S L CHEN P D LIU D J | 2005 | Euphytica2005，145，： | 1 |
| 17 | Anesthetic preconditioning as the alternative to ischemic preconditioning显示文摘 | Lange M Roewer N Kehl F | 2006 | J Thorac Cardiovasc Surg2006，131，1： | 1 |
| 18 | Comparison of aminolevulinic acid and hexylester aminolevulinate induced protoporphyrin IX distribution in human bladder cancer 显示文摘 | Marti A Jichlinski P Lange N | 2003 | J Urol2003，170，： | 1 |
| 19 | Truncating mutations of HSNF5/INI1 in aggressive paediatric cancer显示文摘 | Versteege I Sevenet N Lange J | 1998 | Nature1998，394，6689： | 1 |
| 20 | Bacterial colonization immediately after installation on oral titanium implants 显示文摘 | Furst M M Salvi G E Lang N P | 2007 | Clin Oral Implants Res2007，18，： | 1 |
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