维普中文期刊产品整合服务
13篇 您的检索式:作者名="Lapauw"
    题名 作者 年代 出处 被引量
1Serum estradiol is associated with volumetric bone mineral density an d modulates the impact ofphysical activity on bone size at the age ofpeak bonemass : A study in healthy male siblings 显示文摘LAPAUW B M TAES Y BOGAERT V 2009Joumal of Bone and Mineral Reseach2009,24,6:1
2Estrogen-specific action on bone geometry and volumetric bone density: longitudinal ob- servations in an adult with complete androgen insensitivity 显示文摘Taes Y Lapauw B Vandewalle S 2009Bone2009,45,:1
3Chemerin as biomarker for insulin sensitivity in males without typical characteristics of metabolic syndrome 显示文摘Ouwens DM Bekaert M Lapauw B 2012Arch Physiol Biochem2012,118,3:1
4Current and future treatments of osteoporosis in men显示文摘Kaufman JM Lapauw B Goemaere S 2014Best Pract Res Clin Endocrinol Metab2014,28,6:1
5Body composition,volumetric and areal bone parameters in male-to-female transsexual persons显示文摘Lapauw B Taes Y Simoens S 2008Bone2008,43,6:1
6Thyroid hormone status within the physiological range affects bone mass and density in healthy men at the age of peak bone mass显示文摘Roef G Lapauw B Goemaere S 0,,6:1
7Body composition and metabolic parameters are associated with variation in thyroid hormone levels among euthyroid young men显示文摘Roef G Lapauw B Goemaere S 2012Eur J Endo- erinol2012,167,5:1
8Chemerin as biomarker for insulin sensitivity in males without typical characteristics of metabolic syndrome显示文摘Ouwens DM Bekaert M Lapauw B 0,,03:1
9Chemerin as biomarker for insulin sensitivity in males without typical ~haracteristics of metabolic syndrome显示文摘Ouwens DM Bekaert M Lapauw B et d 2012Arch Physiol Bio- ~hem2012,118,3:1
10Serum estradiol is associated with volumetric bone mineral density and modulates the impact of physical activity on bone size at the age of peak bone mass:A study in healthy male siblings显示文摘Lapauw B M Taes Y Bogaert V 2009Journal of Bone and Mineral Reseach2009,24,6:1
11Fat mass is negatively associated with cortical bone size in young healthy male siblings显示文摘Taes YE Lapauw B Vanbillemont G 0,,07:1
12Sex hor-mone-binding globulin at the crossroad of body composition,somatotropic axis and insulin/glucose homeostasis in younghealthy men显示文摘Vanbillemont G Lapauw B De Naeyer H 2012Clin Endocrinol ( Oxf)2012,76,1:1
13Histologically proven hepatic steatosis associates with lower testosterone levels in men with obesity显示文摘Men with obesity often present with low testosterone(T)and sex hormone-binding globulin(SHBG)levels.Several mechanisms for this have been proposed,but as SHBG is secreted by hepatocytes and sex steroids undergo hepatic metabolization,this study investigates whether severity and histological components of nonalcoholic fatty liver disease(NAFLD)are associated with sex steroid levels in obese men.This cross-sectional study included 80 obese men(age:46±11 years;body mass index:42.2±5.5 kg m^-2).Serum levels of total T and estradiol(E.)were measured using liquid chromatography coupled with tandem mass spectroscopy(LC/MS-MS)and SHBG and gonadotropins by immunoassay.Liver biopsies were evaluated using Steatosis.Activity,and Fibrosis scoring.Participants with steatohepatitis had similar median(1st quartile-3rd quartile)total T levels(7.6[5.0-11.0]nmol l^-1 vs 8.2[7.2-10.9]nmol l^-1;P=0.147),lower calculated free T(cFT)levels(148.9[122.9-188.8]pmol 1-1 s 199.5[157.3-237.6] pmol l^-1;P=0.006),and higher free E.T ratios(10.0[6.4-13.9]×10^-3 vs 7.1[5.7-10.7]×10^-3;P=0.026)compared to men with only nonalcoholic fatty liver.Among the histological components of NAFLD.only steatosis was independently associated with total T(r=-0.331.P=0.003)and cFT levels(r=-0.255.P=0.025).Obese men with.steatohepatitis have even lower cFT levels compared to those without,an association mainly driven by grade of steatosis.Whether this reflects a subgroup of men with a more severe obesity-related phenotype or results from direct relations between hepatic steatosis and sex steroid metabolism needs further investigation.Frederique Van de Velde Marlies Bekaert Anne Hoorens Anja Geerts Guy T'Sjoen Tom Fiers Jean-Marc Kaufman Yves Van Nieuwenhove Bruno Lapauw 2020Asian Journal of Andrology2020,22,3:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费