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2篇 您的检索式：作者名="Larry Croft"

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		题名	作者	年代	出处	被引量
	1	Experimental study of the effect of automated fiber placement induced defects on performance of composite laminates显示文摘	KAVEN CROFT LARRY LESSARD DAMIANO PASINI	2011	Composites : Part A2011，，42：	1
	2	Pseudomonas aeruginosa:Infections and novel approaches to treatment“Knowing the enemy”the threat of Pseudomonas aeruginosa and exploring novel approaches to treatment显示文摘Pseudomonas aeruginosa is an aerobic Gram-negative rod-shaped bacterium with a comparatively large genome and an impressive genetic capability allowing it to grow in a variety of environments and tolerate a wide range of physical conditions.This biological flexibility enables the P.aeruginosa to cause a broad range of infections in patients with serious underlying medical conditions,and to be a principal cause of health care associated infection worldwide.The clinical manifestations of P.aeruginosa include mostly health care associated infections and community-acquired infections.P.aeruginosa possesses an array of virulence factors that counteract host defence mechanisms.It can directly damage host tissue while utilizing high levels of intrinsic and acquired antimicrobial resistance mechanisms to counter most classes of antibiotics.P.aeruginosa co-regulates multiple resistance mechanisms by perpetually moving targets poses a significant therapeutic challenge.Thus,there is an urgent need for novel approaches in the development of anti-Pseudomonas agents.Here we review the principal infections caused by P.aeruginosa and we discuss novel therapeutic options to tackle antibiotic resistance and treatment of P.aeruginosa infections that may be further developed for clinical practice.	Nikhil Sathe Peter Beech Larry Croft Cenk Suphioglu Arnab Kapat Eugene Athan	2023	Infectious Medicine2023，2，3：	0

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