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81篇 您的检索式:作者名="Larry Williams"
    题名 作者 年代 出处 被引量
1Experimental and Modeling Study of Forest Fire Effect on Soil Thermal Conductivity显示文摘An understanding of soil thermal conductivity after a wildfire or controlled burn is important to land management and post-fire recovery efforts. Although soil thermal conductivity has been well studied for non-fire heated soils, comprehensive data that evaluate the long-term effect of extreme heating from a fire on the soil thermal conductivity are limited. The purpose of this study was to evaluate the long-term impact of fire on the effective thermal conductivity of soils by directly comparing fire-heated and no-fire control soils through a series of laboratory studies. The thermal conductivity was measured for ten soil samples from two sites within the Manitou Experimental Forest, Colorado, USA, for a range of water contents from saturation to the residual degree of saturation. The thermal conductivity measured was compared with independent estimates made using three empirical models from literature, including the Campbell et al.(1994), Cté and Konrad(2005), and Massman et al.(2008) models. Results demonstrate that for the test soils studied, the thermal conductivity of the fire-heated soils was slightly lower than that of the control soils for all observed water contents.Modeling results show that the Campbell et al.(1994) model gave the best agreement over the full range of water contents when proper fitting parameters were employed. Further studies are needed to evaluate the significance of including the influence of fire burn on the thermal properties of soils in modeling studies.Kathleen M.SMITS Elizabeth KIRBY William J.MASSMAN Larry Scott BAGGETT 2016Pedosphere2016,26,4:5
2局部缓释IUdR治疗恶性星形细胞瘤实验研究(英文)显示文摘目的研究脑局部缓释125碘标记的5-碘脱氧尿苷(IUdR)的作用。方法为了控制释放125碘-IUdR,合成了25μCi的羧基苯氧丙烷:癸二酸(PCPPSA)(2080)125碘-IUdR聚合体。体外将合成的三聚体缓释剂(10mgPCPPSA)置于37℃磷酸盐缓冲溶液(PBS)中孵育不同时间后移出溶剂并置换为新的PBS,将移出液于放射计数器上测量数值。在体研究采用雄性裸鼠(6周)颅内接种U251人恶性星形细胞瘤及皮下接种对比研究。将颅内荷瘤鼠瘤腔内及皮下接种肿瘤组织内分别应用三聚体缓释剂及空白缓释剂,于不同时间分别测量动物头颅及皮下结节的放射活性,间接定量研究缓释状况;采血了解全身代谢情况。对于多聚磷酸酯(PPE)缓释剂研究采用皮下肿瘤结节内局部应用并测量其缓释的方法,放射自显影研究及全身不同器官缓释剂的吸收代谢研究采用接种后2、4和8d收集标本,分别行切片放射自显影和器官放射活性测定。结果体内和体外研究均显示PCPP:SA缓释剂对125碘-IUdR的控制性释放作用,尤其在体研究分别显示颅内和皮下接种的肿瘤组织对标记的IUdR的释放程度存有极大的差异,提示颅内局部应用的优越性。放射自显影定性研究显示了随距离的增加被标记的IUdR的递减趋势,为确定缓释剂施放部位和间距提供了参考数据。各主要脏器放射性测定的结果显示早期小肠内放射性较高,其次为脾脏,提示IUdR主要的代谢渠道,为处理应用其而可能引发的其他脏器损害或作用提供了线索。结论放射标记的IUdR缓释剂主要集中在接种部位且缓释作用确切。马晓东 Jerry R.Williams Larry E.Dillehay Jeffery A Williams 2005中华神经外科疾病研究杂志2005,4,4:3
3抑郁症的非药物治疗:系统性综述与证据图显示文摘背景抑郁症非药物治疗的疗效比较目前仍然不清楚。方法我们对一些系统性综述作了概述,回顾了随机对照试验(RCT),比较抑郁症非药物治疗的有效性和认知行为治疗(CBT)。对多个电子数据库在2016年2月之前发表的所有文献进行了检索,不限制语言。成对的评阅人进行资料纳入、数据提炼并评估偏倚的风险。在适用的时候进行了荟萃分析。结果我们收录了367项RCT,纳入了约2000名患者,进行了11种治疗,导出17项独立的头对头比较。通过标准化的量表评估,发现CBT、自然疗法、行为干预与躯体活动干预可以降低抑郁的严重程度。然而,这些非药物干预的相对疗效仍然缺乏。这些干预对临床缓解和复发的效果不清楚。CBT的发生率比抗抑郁药物更低。局限性由于证据缺乏一致性、证据不清或偏倚风险高,导致证据的质量只是低到中等,限制了我们研究结果的可信度。结论抑郁症的非药物治疗能减少抑郁症状,在轻度到重度抑郁症患者中,应当合并抗抑郁药物治疗,一同进行。对于非药物治疗的选择,应当根据患者的价值观、偏好、临床和社会因素来与患者共同作出决定。Wigdan H Farah Mouaz Alsawas Maria Mainou Fares Alahdab Magdoleen H Farah Ahmed T Ahmed Essa A Mohamed Jehad Almasri Michael R Gionfriddo Ana Castaneda-Guarderas Khaled Mohammed Zhen Wang Noor Asi Craig N Sawchuk Mark D Williams Larry J Prokop M Hassan Murad Annie LeBlanc 2017英国医学杂志中文版2017,20,11:2
4Advances in the use of terminal restriction fragment length polymorphism (T-RFLP) analysis of 16S rRNA genes to characterize microbial communities显示文摘Ursel M. E. Schütte Zaid Abdo Stephen J. Bent Conrad Shyu Christopher J. Williams Jacob D. Pierson Larry J. Forney 2008Applied Microbiology and Biotechnology2008,,3:1
5Tread compounds with highly-dispersible silica显示文摘Larry R E William C Fultz J M 1998Rubb World1998,219,2:1
6Hydrocarbon fuels from vegetable oils via hydrolysis and thermo-catalytic decarboxylation显示文摘Wei-Cheng Wang Nirajan Thapaliya Andrew Campos Larry F. Stikeleather William L. Roberts 2011Fuel2011,,:1
7Does Preoperative Percutaneous Biliary Drainage Reduce Operative Risk or Increase Hospital Cost?显示文摘HENRY A. PITT ANTOINETTE S. GOMES JUAN F. LOIS LINDA L. MANN LARRY S. DEUTSCH WILLIAM P. LONGMIRE 1985Annals of Surgery1985,,5:1
8Overview of the fundamental reactions and degradation mechanisms of NOx storage/reduction catalysts 显示文摘William S Epling Larry E Campbell Aleksey Yezerets 2004Catalysis Reviews2004,46,2:1
9Effects of 17-allylamino-17-demethoxygeldanamycin (17-AAG) in transgenic mouse models of frontotemporal lobar degeneration and Alzheimer’s disease显示文摘Alzheimer’s disease(AD),the most common dementia,is characterized by potentially neurotoxic aggregation of Aβ peptide and tau protein,and their deposition as amyloid plaques and neurofibrillary tangles(NFTs).Tau aggregation also occurs in other common neurodegenerative diseases.Frontotemporal dementia(FTD)can be caused by tau mutations that increase the susceptibility of tau to hyperphosphorylation and aggregation,which may cause neuronal dysfunction and deposition of NFTs.17-allylamino-17-demethoxygeldanamycin(17-AAG)is a potent inhibitor of heat shock protein 90(Hsp90),a cytosolic chaperone implicated in the proper folding and functions of a repertoire of client proteins.17-AAG binds to Hsp90 and enhances degradation of Hsp90 client protein.We sought to determine whether 17-AAG can reduce Aβ and tau pathology in the brains of AD and FTD model mice expressing Aβ or P301L mutant tau,respectively.Mice were randomized to receive 25,5,or 0 mg/kg 17-AAG thrice weekly from age eight to 11 months.Analysis was performed by rotarod test on motor function,on the area occupied by plaques in hippocampus or NFTs in medulla tissue sections,and on mortality.A high dose of 17-AAG tended to decrease NFTs in male mice(p=0.08).Further studies are required to confirm the effect of 17-AAG in diseases of tau aggregation.Shuk Wai Ho Yuk Tung Chanel Tsui Ting Ting Wong Stanley Kwok-Kuen Cheung William B Goggins Lau Ming Yi Kwok Kin Cheng Larry Baum 2013Translational Neurodegeneration2013,2,1:1
10The effect of rootstock and applied water on vine water atatus and gas eschang of Cabemet Sauvignon显示文摘ABU-HILAL I COLLESANO G LARRY E WILLIAMS 2000Acta Horticulture2000,,526:1
11A quantitative of DNA extraction and purification from compost显示文摘Michael H William C G Larry P W 2003Journal of Microbiological Method2003,54,:1
12Real-time continual Leveal of detail rendering of height fields 显示文摘P Lindstrom David Koller William Ribarsky Larry F Hodges Nick Faust Gregory A Turner 1996In Proceedings of ACM SIGGRAPH 961996,,:1
13Vascular Smooth Muscle Cells Derived from Atherosclerotic Human Arteries Exhibit Greater Adhesion, Migration, and Proliferation Than Venous Cells显示文摘Peter L. Faries Darren I. Rohan Mark C. Wyers Michael L. Marin Larry H. Hollier William C. Quist Frank W. LoGerfo 2002Journal of Surgical Research2002,,1:1
14Treatment outcome of late steroid-resistant nephrotic syndrome: a study by the Midwest Pediatric Nephrology Consortium显示文摘Caroline Straatmann Rose Ayoob Rasheed Gbadegesin Keisha Gibson Michelle N. Rheault Tarak Srivastava Cheryl L. Tran Debbie S. Gipson Larry A. Greenbaum William E. Smoyer V. Matti Vehaskari 2013Pediatric Nephrology2013,,8:1
15A Randomized, Controlled Pilot Study of Autologous CD34+ Cell Therapy for Critical Limb Ischemia显示文摘Douglas W. Losordo Melina R. Kibbe Farrell Mendelsohn William Marston Vickie R. Driver Melhem Sharafuddin Victoria Teodorescu Bret N. Wiechmann Charles Thompson Larry Kraiss Teresa Carman Suhail Dohad Paul Huang Candice E. Junge Kenneth Story Tara Weistro 2012Circulation: Cardiovascular Interventions2012,,6:1
16Montelukast Reduces Asthma Exacerbations in 2 to 5 year-Old Children with intermittent Asthma显示文摘Todd D Green and Larry W Williams 2006Pediatrics2006,118,:1
17Tire tread compounds with silica/CB blends显示文摘Fultz William C Evans Larry R 1998Rubber World1998,218,1:1
18The copper-catalyzed addition of arenesulfonyl chlorides to conjugated dienes, trienes, and phenylacetylene 显示文摘WILLIAM E CHRISTIAN T LARRY W 1972Journal of Organic Chemistry1972,35,12:1
19Interaction of applied water amounts and leaf removal in the fruiting zone on grapevine water relations and productivity of Merlot显示文摘Larry Williams 2012Irrigation Science2012,,5:1
20The Management of the Open Abdomen in Trauma and Emergency General Surgery: Part 1—Damage Control显示文摘Jose J. Diaz Daniel C. Cullinane William D. Dutton Rebecca Jerome Richard Bagdonas Jarolslaw O. Bilaniuk Bryan R. Collier John J. Como John Cumming Maggie Griffen Oliver L. Gunter John Kirby Larry Lottenburg Nathan Mowery William P. Riordan Niels Martin J 2010The Journal of Trauma: Injury, Infection, and Critical Care2010,,6:1
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