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| 1 | Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis显示文摘Background Stroke is a major cause of death or long-term disability worldwide.Many patients with stroke receive integrative therapy consisting of Western medicine(WM)and routine rehabilitation in conjunction with Chinese medicine(CM),such as acupuncture and Chinese herbal medicine.However,there is no available evidence on the effectiveness of the combined use of WM and CM interventions in stroke rehabilitation.Aims The purpose of this meta-analysis is to evaluate the results of all individual studies to assess the combined use of CM and WM in stroke rehabilitation compared with WM only.Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines were followed.MEDLINE,EMBASE,Cochrane and China National Knowledge Infrastructure(CNKI)were searched.The included outcomes were dependency,motor function,depression and swallowing function.Subgroup analysis was performed,and publication bias was assessed using funnel plots.Summary of review 58 studies and 6339 patients were included in the meta-analysis.Subgroup analysis revealed that combined therapy comprising both acupuncture and WM had a superior effect on improving dependency and swallowing function compared with standard WM therapy alone.Potential superiority of combined therapy comprising CM and WM in improving depression compared with standard WM therapy was also found.Conclusions Our results indicate that the combined use of CM and WM could be more efficacious in stroke rehabilitation compared with the use of WM therapy alone.However,most studies were short in duration(2 to 4 weeks)and prone to different types of biases,which prevents making any conclusion regarding the long-term effects and raises concerns regarding true efficacy in context of high likelihood of Hawthorn bias.So,more randomised controlled trials with more rigorous design and longer duration of treatment and follow-up need to be conducted to compare WM alone versus WM and CM combined. | Linda LD Zhong Ya Zheng Alexander Y Lau Norman Wong Liang Yao Xingyao Wu Tengteng Shao Zhenxing Lu Huijuan Li Chun Sum Yuen Jianwen Guo Suzanne Lo Janita Chau Kam Wa Chan Bacon Fung Leung Ng Zhaoxiang Bian Edwin Chau-leung Yu | 2022 | Stroke & Vascular Neurology2022，7，1： | 7 |
| 2 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng FRCSEd (Gen) Ka Lau Leung MD FRCS (Edin) Janet F. Y. Lee MD FRCSEd (Gen) Raymond Y. C. Yiu FRCSEd (Gen) Jimmy C. M. Li FRACS Anthony Y. B. Teoh MRCS (Edin) Wing Wa Leung MSc | 2008 | Annals of Surgical Oncology2008，，9： | 2 |
| 3 | Acute mesenteric ischemi- a :a clinical review显示文摘 | Oldenburg WA Lau LL Rodenberg TJ | 2004 | Arch Intern Med2004，164，10： | 1 |
| 4 | Acute mesenteric ischaemia: a clinical review显示文摘 | Oldenburg WA Lau LL Rodenberg TJ | 2004 | Arch Intern Med2004，164，10： | 1 |
| 5 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng FRCSEd (Gen) Ka Lau Leung MD FRCS (Edin) Janet F. Y. Lee MD FRCSEd (Gen) Raymond Y. C. Yiu FRCSEd (Gen) Jimmy C. M. Li FRACS Anthony Y. B. Teoh MRCS (Edin) Wing Wa Leung MSc | 2008 | Annals of Surgical Oncology2008，，9： | 1 |
| 6 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng Ka Lau Leung Janet F. Y. Lee Raymond Y. C. Yiu Jimmy C. M. Li Anthony Y. B. Teoh Wing Wa Leung | 2008 | Annals of Surgical Oncology2008，，9： | 1 |
| 7 | Laparoscopic-assisted versus open total mesorectal excision with anal sphincter preservation for mid and low rectal cancer: a prospective, randomized trial显示文摘 | Simon S. M. Ng Janet F. Y. Lee Raymond Y. C. Yiu Jimmy C. M. Li Sophie S. F. Hon Tony W. C. Mak Dennis K. Y. Ngo Wing Wa Leung Ka Lau Leung | 2014 | Surgical Endoscopy2014，，1： | 1 |
| 8 | Acute mesenteric ischemia: a clinical review显示文摘 | 01denburg WA Lau LL Rodenberg TJ | 2004 | Arch Intern Med2004，164，10： | 1 |
| 9 | Pharmacological characterization of endothelin receptor subtypes in the guinea-pig prostate gland显示文摘 | Lau WA Cox SL Pennefather JN | 1999 | Br J Pharmacol1999，127，5： | 1 |
| 10 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng FRCSEd (Gen) Ka Lau Leung MD FRCS (Edin) Janet F. Y. Lee MD FRCSEd (Gen) Raymond Y. C. Yiu FRCSEd (Gen) Jimmy C. M. Li FRACS Anthony Y. B. Teoh MRCS (Edin) Wing Wa Leung MSc | 2008 | Annals of Surgical Oncology2008，，9： | 1 |
| 11 | The contractile effects of endothelins on the smooth muscle of the rat prostate gland显示文摘 | Salamoussa A Lau WA | 2000 | European Journal of Pharmacology2000，403，12： | 1 |
| 12 | Acute mesenteric ischemia:a clinical review显示文摘 | Oldenburg WA Lau LL Rodenberg TJ | 2004 | Arch Intern Med2004，164，10： | 1 |
| 13 | Acute mesenteficischemia:aclinicalre view显示文摘 | Oldenburg WA Lau LL Redenberg TJ et a1 | 2004 | Amh Intem Med2004，164，10： | 1 |
| 14 | Emergency Laparoscopic-assisted versus Open Right Hemicolectomy for Obstructing Right-sided Colonic Carcinoma: A Comparative Study of Short-term Clinical Outcomes显示文摘 | Simon S. M. Ng Janet F. Y. Lee Raymond Y. C. Yiu Jimmy C. M. Li Wing Wa Leung Ka Lau Leung | 2008 | World Journal of Surgery2008，，3： | 1 |
| 15 | Acute mesenteric ischemia:a clinical review 显示文摘 | Oldenburg WA Lau LL Rodenberg TJ | 2004 | Arch intern med2004，164，10： | 1 |
| 16 | Acute mesenteric ischemia: a clinical review显示文摘 | Oldenburg WA Lau LL Rodenberg TJ | 2004 | Arch Intern Med2004，164，10： | 1 |
| 17 | Acute mesenteric ischemia:a clinical review显示文摘 | Oldenburg WA Lau LL Rodenberg TJ | 2004 | Arch Intern Med2004，164，： | 1 |
| 18 | Acute mesenteric ischemia :a ehinical review显示文摘 | Oldenburg WA Lau LL Rodenberg TJ | 2004 | Arch Intern Med2004，164，： | 1 |
| 19 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng FRCSEd (Gen) Ka Lau Leung MD FRCS (Edin) Janet F. Y. Lee MD FRCSEd (Gen) Raymond Y. C. Yiu FRCSEd (Gen) Jimmy C. M. Li FRACS Anthony Y. B. Teoh MRCS (Edin) Wing Wa Leung MSc | 2008 | Annals of Surgical Oncology2008，，9： | 1 |
| 20 | Karyotype/pheno- type correlation in partial trisomies of the long ann of chromosome 16: case report and review of literature显示文摘 | Laus AC Baratela WA Laureano LA | 2012 | Am J Med Genet A2012，158，4： | 1 |
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