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| 1 | Rationale for the potential use of mesenchymal stromal cells in liver transplantation显示文摘Mesenchymal stromal cells(MSCs) are multipotent and self-renewing cells that reside essentially in the bone marrow as a non-hematopoietic cell population, but may also be isolated from the connective tissues of most organs. MSCs represent a heterogeneous population of adult, fibroblast-like cells characterized by their ability to differentiate into tissues of mesodermal lineages including adipocytes, chondrocytes and osteocytes. For several years now, MSCs have been evaluated for their in vivo and in vitro immunomodulatory and ‘tissue reconstruction' properties, which could make them interesting in various clinical settings, and particularly in organ transplantation. This paper aims to review current knowledge on the properties of MSCs and their use in pre-clinical and clinical studies in solid organ transplantation, and particularly in the field of liver transplantation. The first available clinical data seem to show that MSCs are safe to use, at least in the medium-term, but more time is needed to evaluate the potential adverse effects of long-term use. Many issues must be resolved on the correct use of MSCs. Intensive in vitro and pre-clinical research are the keys to a better understanding of the way that MSCs act, and to eventually lead to clinical success. | Morgan Vandermeulen Céline Grégoire Alexandra Briquet Chantal Lechanteur Yves Beguin Olivier Detry | 2014 | World Journal of Gastroenterology2014，20，44： | 2 |
| 2 | HSV -1 thymidine kinase gene therapy for colorectal adenocarcinoma - derived peritoneal carcinomatosis 显示文摘 | Lechanteur C Princen F Lo Bue S | 1997 | Gene Ther1997，4，11： | 1 |
| 3 | Association of smoking and CFH and ARMS2 risk variants with younger age at onset of neovascular age related macular degeneration 显示文摘 | Lechanteur YT van de Camp PL Smailhodzie D | 2015 | JAMA Ophthalmol2015，133，5： | 1 |
| 4 | Cotransplantation of mesenehyrnal stem cells might prevent death from graftversus- host disease (GVHD) without abrogating graft-versus tumor effects after HLA-mismatched allogeneie transplantation following nonmyeloablative conditioning显示文摘 | Baron F Lechanteur C Willems E | 2010 | Blood and Marrow Transplant2010，16，6： | 1 |
| 5 | Cytosine deaminase suicide gene therapy for peritoneal carcinomatosis 显示文摘 | Bentires-Alj M Hellin AC Lechanteur C | 2000 | Cancer Gene Ther2000，7，1： | 1 |
| 6 | Cytosine deaminase suicide gene therapy for peritoneal carcinomatosis 显示文摘 | Bentires-Alj M Hellin AC Lechanteur C | 2000 | Cancer Gene Ther2000，7，1： | 1 |
| 7 | Cytosine deaminase suicide gene therapy for peritoneal carcinomatosis 显示文摘 | Bentires-Alj M Hellin AC Lechanteur C | 2000 | Cancer Gene Ther2000，7，1： | 1 |
| 8 | Cotransplantation of mesenchymal stem cells might prevent death from graft-versus-host disease(GVHD)without abrogating graft-versus-tumor effects after HLA-mismatched allogeneic transplantation following nonmyeloablative conditioning显示文摘 | Baron F Lechanteur C Willems E | | 0，，： | 1 |
| 9 | Cytosine deaminase suicide gene therapy for peritoneal carcinomatosis 显示文摘 | Bentires-Alj M Hellin AC Lechanteur C | 2000 | Cancer Gene Ther2000，7，1： | 1 |
| 10 | HSV-1 thymidine Kinase gene therapy for peritoeal carcinomatosis显示文摘 | Lechanteur C Princen F Lo Bue S | 1998 | Adv Exp Med Biol1998，451，11： | 1 |
| 11 | HSV-1 thymidine kinase gene therapy for peritoneal carcinomatosis 显示文摘 | Lechanteur C Princen F Lo Bue S | 1998 | Adv Exp Med Biol1998，451，： | 1 |
| 12 | Genetic, behavioral,and sociodemographic risk factors for second eye progression in age-related macular degeneration 显示文摘 | Lechanteur YT van de Ven JP Smailhodzic D | 2012 | Invest Ophthahnol Vis Sci2012，53，9： | 1 |
| 13 | Cytosine deaminase suicide gene therapy for peritoneal carcinomatosis显示文摘 | Bentires-Alj M Hellin AC Lechanteur C | 2000 | Cancer Gene Ther2000，7，1： | 1 |
| 14 | Impact of bone marrow-derived mesenchymal stromal cells on experimental xenogeneic graft-versus-host disease显示文摘 | Bruck F Belle L Lechanteur C | 2013 | Cytotherapy2013，15，3： | 1 |
| 15 | Cotransplantation of mesenchymal stem cells mighttprevent death from graft-versus-host disease(GVHD)without abrogating graft-versus-tumor effects after HLA-mismatched allogeneic transplantation following nonmyeloablative conditioning显示文摘 | Baron F Lechanteur C Wil ems E | | 0，，： | 1 |
| 16 | Cotransplantation of mesen- chymal stem cells might prevent death from graft-versus-host disease (GVHD) without abrogating graft-versus-tumor effects after HLA-mis- matched allogeneic transplantation following nonmyeloablative condi- tioning显示文摘 | Baron F Lechanteur C Willems E | 2010 | Biol Blood Marrow Transplant2010，16，6： | 1 |
| 17 | Cotransplantation ofmesenchymal stem cells might prevent death from graftversus-host disease (GVHD) without abrogating graft-versus tumoreffects after HLA-mismatched allogeneic transplantationfollowing nonmyeloablative conditioning 显示文摘 | Baron F Lechanteur C Willems E | 2010 | Biol BloodMarrow Transplant2010，16，6： | 1 |
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