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| 1 | Epidemiology of hepatitis B virus infection among young adults in Taiwan,China after public vaccination program显示文摘背景肝炎 B 病毒( HBV )的公共种痘程序在台湾在 1984 期间被运行, China.However ,在比 15 岁老的青少年之中的 HBV 种痘的长持续的保护的功效是很少, recorded.Methods A seroepidemiological 调查在台湾在 4575 个第一年的大学学生之中被进行,中国包括由严峻的 HBV 表面抗原( HBsAg )的 HBV 的血清学的数据,在 2000~2003 期间出现抗体( anti-HBs ), HBV 核心抗体( anti-HBc )并且在东方台湾的男、女的学生让最高的 HBsAg 搬运人与另外的地方相比评价。使用多重逻辑回归分析,与在 1984 年 7 月以后出生的学生,相比调整或 HBsAg,搬运人率为从 1983 年 7 月出生的学生为在 1981 年 6 月前出生的学生从 3.10 减少了到 1.56 到 1984 年 6 月(95%CI 1.96-4.91, P0.001;95%C/1.06-2.28, P=0.024;分别地).Conclusions 公众种痘再提供长持续的保护在在台湾的大学学生之中的 HBV 感染,比 18 岁旧的中国。有在在台湾的年轻成年人之中的 HBV 感染的一个地理变化,中国。 | CHEN Chun-Chieh YEN Chi-Hua WU Wei-Ya HU Suh-Woan CHEN Shiuan-Chih William R. Bell LEE Meng-Chih | 2007 | Chinese Medical Journal2007，，13： | 6 |
| 2 | Long-term outcomes after fractional flow reserve-guided percutaneous coronary intervention in patients with severe coronary stenosis显示文摘Objective To explore the safety and efficacy of FFR-guided percutaneous coronary intervention (PCI) in vessels with severe diameter stenosis. Methods & Results Of 1090 patients undergoing fractional flow reserve (FFR) assessment from 2002 to 2009,we identified 167 patients in whom FFR was measured in at least one 70%–89% stenotic lesion. These patients were subdivided into an FFR-defer group (n = 49) if PCI was deferred (FFR > 0.80),and an FFR-perform group (n = 118) if PCI was performed (FFR ≤ 0.80). Comparatively,an additional 1176 patients undergoing PCI in at least one lesion with 70%–89% stenosis but without measurement of FFR served as a control (angiography- guided) group. Clinical outcomes were compared during a median follow-up of 49.0 months. The 5-year Kaplan-Meier estimated revascularization rates were 16% in the FFR-defer group and 33% in the FFR-perform group (P = 0.046). The incidence of major adverse cardiac events were comparable in these two groups (HR = 0.82,95% CI: 0.37–1.82,P = 0.63). The number of stents placed was significantly lower in the FFR-guided group (0.9 ± 0.8 vs. 1.4 ± 0.8,P < 0.001). Conclusions Functional revascularization for lesions with visually severe stenosis is clinically safe and associated with fewer stents use. This study suggests that extending the use of FFR to more severe coronary lesions may be reasonable. | Ying-Hua ZHANG Jing LI Andreas J. Flammer Yoshiki Matsuo Moo-Sik Lee Ryan J. Lennon Malcolm R. Bell David R. Holmes John F. Bresnahan Charanjit S. Rihal Lilach O. Lerman Amir Lerman | 2019 | Journal of Geriatric Cardiology2019，16，4： | 2 |
| 3 | Monitoring dioxins and PCBs in eggs as sensitive indicators for environmental pollution and global contaminated sites and recommendations for reducing and controlling releases and exposure显示文摘This review compiles information on PCDD/F-and PCB-contaminated eggs from 20 years of global egg monitoring around emission sources in four continents conducted by the International Pollutants Elimination Network(IPEN)and Arnika as well as a compilation of data from scientific literature.IPEN monitored 127 pooled egg samples including samples from 113 chicken flocks at potential PCDD/F-and PCB-contaminated sites around priority sources listed in the Stockholm Convention(e.g.waste incinerators,metal industries,cement plants,and open burning).99(88%)of pooled egg samples were above the EU maximum limits for PCDD/Fs(2.5 pg PCDD/F-TEQ/g fat)or the sum of PCDD/Fs and dioxinlike PCBs(5 pg PCDD/F-PCB-TEQ/g fat).Children consuming such eggs exceed the tolerable weekly intake(TWI).This demonstrates that close to 90%of these areas were not safe for the production of free-range eggs.Sixteen out of the 113 egg samples(14%)were contaminated above 50 pg TEQ/g fat and exceeded the EU maximum limit more than 10 times.From the 26 pooled egg samples around incinerators 24(92%)exceeded the limit with a mean of 43.1 pg TEQ/g fat(2.6e234 pg TEQ/g).All 21 egg samples around metal industries(4.4e112.6 pg TEQ/g fat)were above limits with mean concentration of 26.0 pg TEQ/g fat.Also all 7 egg samples measured at e-waste recycling sites were above limits(mean 308 pg TEQ/g fat).In 58(51%)pooled egg samples the PCB-TEQ was above 5 pg TEQ/g fat exceeding the EU maximum limit with dioxin-like PCBs alone.This highlights the role of commercial PCBs for global contamination with dioxin-like compounds.It was discovered that around metal industries,shredder plants,open burning sites of e-waste and dump sites,a high share of contamination was caused by dl-PCBs.This clearly shows severe PCB release from the end-of-life management of PCB-containing equipment in developing countries.Also highly contaminated eggs were found at many sites where plastic was incinerated.The highest contaminated egg sample ever measured came from an e-waste site in Ghana and had 856 pg TEQ/g fat plus 300 pg TEQ from brominated dioxins(PBDD/Fs).Other extreme PCDD/F contaminations of eggs were found at a chlor-alkali site(514 pg TEQ/g fat),Agent Orange contaminated areas in Vietnam(490,249 and 246 pg TEQ/g fat)and e-waste sites(568 and 520 pg TEQ/g fat).Where DR CALUX®bioassay revealed higher TEQ compared to measured PCDD/F-PCB-TEQ in IPEN studies,polybrominated PBDD/F were also measured and detected up to 300 pg TEQ/g fat at e-waste sites.One positive outcome from the IPEN studies is that all 10 pooled supermarket eggs in developing countries were below regulatory limit.Policy recommendations are made including:a systematic assessment of areas around PCDD/Fs and PCBs sources;measures for reduction of exposures of populations;urgent control of emission sources including PCB equipment,the open burning of plastic,and the use of plastic as fuel in boilers/incinerators in developing countries without air pollution control.Furthermore,soil limits need to be re-assessed and lowered for free-range poultry. | Jindrich Petrlik Lee Bell Joe DiGangi Serge Molly Allo'o Allo'o Gilbert Kuepouo Griffins Ochieng Ochola Valeriya Grechko Nikola Jelinek Jitka Strakova Martin Skalsky Yuyun Ismawati Drwiega Jonathan N.Hogarh Eric Akortia Sam Adu-Kumi Akarapon Teebthaisong Maria Carcamo Bjorn Beeler Peter Behnisch Claudia Baitinger Christine Herold Roland Weber | 2022 | Emerging Contaminants2022，8，1： | 2 |
| 4 | Bolus or slow titrated injection of midazolam prior to upper gastrointestinal endoscopy? Relative effect on oxygen saturation and prophylactic value of supplemental oxygen 显示文摘 | Bell GD Antrobus JH Lee J | 1990 | Aliment Pharmacol Ther1990，4，： | 1 |
| 5 | A unifying information-theoretic framework for independent component analysis 显示文摘 | GIROLAMI M BELL A J | 2000 | Comput & Math Appl2000，，39： | 1 |
| 6 | Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans显示文摘 | Mark J. Graham Richard G. Lee Thomas A. Bell Wuxia Fu Adam E. Mullick Veronica J. Alexander Walter Singleton Nick Viney Richard Geary John Su Brenda F. Baker Jennifer Burkey Stanley T. Crooke Rosanne M. Crooke | 2013 | Circulation Research2013，，11： | 1 |
| 7 | Effect of sequence varia-tion in Plasmodium falciparum histidine - rich protein 2on binding of specific monoclonalantibodies : Implica-tions for rapid diagnostic tests for malaria显示文摘 | Lee N Baker J Bell D | 2006 | J Clin Mi-crobiol2006，44，8： | 1 |
| 8 | Vitamin D deficiency: animportant, common, and easily treatable cardiovascular riskfactor显示文摘 | Lee JH O'Keefe JH Bell D | 2008 | J Am Coll Cardiol2008，52，24： | 1 |
| 9 | Differences in cell proliferation and prognostic significance of proliferating cell nuclear antigen and Ki-67 antigen immunoreactivity in situ and invasive carcinomas of the extrahepatic tract显示文摘 | Lee CS Hua SW Bell DH | 2005 | Cancer2005，78，： | 1 |
| 10 | Thydrodenitrogenation of quinoline over high-surface-area Mo2N显示文摘 | Lee K S Abe H Reimer J A Bell A | 2010 | Catal2010，139，： | 1 |
| 11 | A unifying information theoretical framework for independent component analysis显示文摘 | Lee T W Girolami M Bell A J | 2000 | Computers and Mathematics with Application2000，31，11： | 1 |
| 12 | Antisense oligonucleotide inhibition of apolipoprotein C-Ⅲ reduces plasma triglycerides in rodents,nonhuman primates,and humans显示文摘 | Graham MJ Lee RG Bell TA 3rd | | 0，，： | 1 |
| 13 | Vitamin D Deficiency显示文摘 | John H. Lee James H. O’Keefe David Bell Donald D. Hensrud Michael F. Holick | 2008 | Journal of the American College of Cardiology2008，，24： | 1 |
| 14 | Quantitative analysis of multidrug resisrance gene expression in human osteosarcoma显示文摘 | Nobel-Topham SE Bell RS | 1996 | Br J Cancer1996，74，7： | 1 |
| 15 | Adverse reactions to OsteoSet bone graft substitute,the incidence in a consecutive series显示文摘 | Lee GH Khoury JG Bell JE | 2002 | Iowa Orthop J2002，22，： | 1 |
| 16 | Use of satellite-based aerosol optical depth and spatial clustering to predict ambient PMz concentrations显示文摘 | Lee H J Coull BA Bell ML | 2012 | Environ Res2012，118，10： | 1 |
| 17 | Vitamin D deficiency animportant, common, and easily treatable cardiovascular riskfactor-显示文摘 | Lee JH O'Keefe JH Bell D | 2008 | J Am Coll Cardiol2008，52，24： | 1 |
| 18 | Antisense oligonucleotide inhibition of apolipoprotein C-Ⅲ reduces plasma triglycerides in rodents, nonhuman primates, and humans显示文摘 | Graham M J Lee RG Bell TA 3rd | 2013 | Circ Res2013，112，11： | 1 |
| 19 | X chromosome inactivation patterns in normal and X-linked hereditary nephropathy cartier dogs显示文摘 | Bell RJ Lees GE Murphy KE | 2008 | Cytogenet Genome Res2008，122，1： | 1 |
| 20 | Effect of Hypercarbia and Isoflurane on Brain Cell Death and Neurocognitive Dysfunction in 7-day-old Rats显示文摘 | Greg Stratmann Laura D. V. May Jeffrey W. Sall Rehan S. Alvi Joseph S. Bell Brandi K. Ormerod Vinuta Rau Joan F. Hilton Ran Dai Michael T. Lee Kavel H. Visrodia Ban Ku Emanuel J. Zusmer Jeremy Guggenheim Atoosa Firouzian | 2009 | Anesthesiology2009，，4： | 1 |
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