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| 1 | Akinetic freezing and trick move- ments in Parkinson's disease 显示文摘 | Stern G Lander C Lees A | 1980 | J Neural Transm Suppl1980，，16： | 1 |
| 2 | Challenge tests to predict the dopaminergic response in untreated Parkinson's disease显示文摘 | Hughes AJ Lees AJ Stern GM | 1991 | Neurology1991，41，： | 1 |
| 3 | Challenge tests to predict the dopaminergic response in untreated Parkinson's disease显示文摘 | Hughes AJ Lees AJ Stern GM | 1991 | Neurology1991，41，： | 1 |
| 4 | United States-based practice patterns and resource utilization in advanced neuroendocrine tumor treatment显示文摘AIM: To assess advanced neuroendocrine tumor (NET) treatment patterns and resource utilization by tumor progression stage and tumor site in the United States. METHODS: United States Physicians meeting eligibility criteria were provided with online data extraction forms to collect patient chart data on recent NET patients. Resource utilization and treatment pattern data were collected over a baseline period (after diagnosis and before tumor progression), as well as initial and secondary progression periods, with progression defined according to measureable radiographic evidence of tumor progression. Resource categories used in the analysis include: Treatments (e.g. , surgery, chemotherapy, radiotherapy, targeted therapies), hospitalizations and physician visits, diagnostic tests (biomarkers, imaging, laboratory tests). Comparisons between categories of resource utilization and tumor progression status were examined using univariate (by tumor site) and multivariate analyses (across all tumor sites). RESULTS: Fifty-five physicians were included in the study and completed online data extraction forms using the charts of 110 patients. The physician sample showed a relatively even distribution for those affiliated with academic versus community hospitals (46% vs 55%). Forty (36.3%) patients were reported to have pancreatic NET (pNET), while 70 (63.6%) patients had gastrointestinal tract (GI)/Lung as the primary NET site. Univariate analysis showed the proportion of patients hospitalized increased from 32.7% during baseline to 42.1% in the progression stages. While surgeries were performed at similar proportions overall at baseline and progression, pNET patients, were more likely than GI/Lung NET patients to have undergone surgery during the baseline (33.3% vs 25.0%) and any progression periods (26.7% vs 23.4%). While peptide-receptor radionuclide and targeted therapy utilization was low across NET types and tumor stages, GI/Lung types exhibited greater utilization of these technologies compared to pNET. Chemotherapy utilization was also greater among GI/Lung types. Multivariate analysis results demonstrated that patients in first progression period were over 3 times more likely to receive chemotherapy when compared to baseline (odds ratio: 3.31; 95%CI: 1.46-7.48, P=0.0041). Further, progression was associated with a greater likelihood of having a study physician visit [relative risk (RR): 1.54; 95%CI: 1.10-2.17, P=0.0117], and an increased frequency of other physician visits (RR: 1.84; 95%CI: 1.10-3.10, P=0.0211). CONCLUSION: Resource utilization in advanced NET in the United States is significant overall and data suggests progression has an impact on resource utilization regardless of NET tumor site. | Jonathan Strosberg Roman Casciano Lee Stern Rohan Parikh Maruit Chulikavit Jacob Willet Zhimei Liu Xufang Wang Krzysztof J Grzegorzewski | 2013 | World Journal of Gastroenterology2013，19，15： | 1 |
| 5 | Sustained low-dose levodopa therapy in Parkinson's disease:a 3-year follow-up显示文摘 | Lees AJ Stern GM | 1983 | Adv Neurol1983，37，： | 1 |
| 6 | Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1显示文摘 | Xu X Lee J Stern DF | | 0，，33： | 1 |
| 7 | Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCAI显示文摘 | Xu X Lee J Stern DF | 2004 | J Biol Chem2004，279，34： | 1 |
| 8 | Advance and prospectus of seasonal prediction: assessment of the APCC/CliPAS 14-model ensemble retrospective seasonal prediction (1980–2004)显示文摘 | Bin Wang June-Yi Lee In-Sik Kang J. Shukla C.-K. Park A. Kumar J. Schemm S. Cocke J.-S. Kug J.-J. Luo T. Zhou B. Wang X. Fu W.-T. Yun O. Alves E. K. Jin J. Kinter B. Kirtman T. Krishnamurti N. C. Lau W. Lau P. Liu P. Pegion T. Rosati S. Schubert W. Stern | 2009 | Climate Dynamics2009，，1： | 1 |
| 9 | AGCM simulations of intraseasonal variability associated with the Asian summer monsoon显示文摘 | D. E. Waliser K. Jin I.-S. Kang W. F. Stern S. D. Schubert M. L. C. Wu K.-M. Lau M.-I. Lee V. Krishnamurthy A. Kitoh G. A. Meehl V. Y. Galin V. Satyan S. K. Mandke G. Wu Y. Liu C.-K. Park | 2003 | Climate Dynamics (-)2003，，5： | 1 |
| 10 | Microcephalin is a DNA damage re sponse protein involved in regulation of CHK1 and BRCA1 显示文摘 | Xu X Lee J Stern DF | 2004 | Biol Chem2004，279，34： | 1 |
| 11 | Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCAI显示文摘 | Xu X Lee J Stern DF | 2004 | J Biol Chem2004，279，34： | 1 |
| 12 | The Prevalence of Undiagnosed HIV Infection in Those Who Decline HIV Screening in an Urban Emergency Department显示文摘 | M. Czarnogorski J. Brown V. Lee J. Oben I. Kuo R. Stern G. Simon Eric Daar | 2011 | AIDS Research and Treatment2011，，： | 1 |
| 13 | Localization of a sulphate-activating system within Euglena mitochondria显示文摘 | SAHIDA T STERN A LEE D | 1985 | Biochem1985，232，： | 1 |
| 14 | Dystonia in Parkinson's disease: clinical and pharmacological features显示文摘 | Poewe WH Lees A J Stern GM | 1988 | Ann Neurol1988，23，： | 1 |
| 15 | Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1显示文摘 | XU X LEE J STERN D F | 2004 | J Biol Chem2004，279，34： | 1 |
| 16 | Use of the vascular closure staple clip applier for microvascular anastomosis in free-flap surgery, 显示文摘 | Cope C Lee K Stern H | 2000 | Plast Reconstr Surg2000，106，1： | 1 |
| 17 | Microcephalin is a DNA damage response protein involved in regulation of CHKI and BRCA1 显示文摘 | Xu X Lee J Stern DF | 2004 | J Biol Chem2004，279，34： | 1 |
| 18 | The Use of Recreation Planning Tools in U.S. Forest Service NEPA Assessments显示文摘 | Lee Cerveny Dale Blahna Marc Stern Michael Mortimer S. Predmore James Freeman | 2011 | Environmental Management2011，，3： | 1 |
| 19 | Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1显示文摘 | Xu X Lee J Stern D F | 2004 | J Biol Chem2004，279，34： | 1 |
| 20 | Glass inclusions in Mariana arc phenocrysts:A new perspective on magmatic evolution in a typical intra-oceanic arc 显示文摘 | Lee J and Stern R J | 1998 | Journal of Geology1998，106，： | 1 |
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