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| 1 | H pylori status and angiogenesis factors in human gastric carcinoma显示文摘AIM: To investigate H pylori expression in gastric cancer patients in relation to primary tumor angiogenic markers, such as microvessel density (MVD), thymidine phospho- rylase (TP), vascular endothelial growth factor receptor-1 (VEGF-R1), p53 and circulating VEGF levels. METHODS: Angiogenic markers were analyzed immu- nohistochemically in 56 primary gastric cancers. H pylori cytotoxin (vacA) and the cytotoxin-associated gene (cagA) amplification were evaluated using PCR assay. Serum H pylori IgG antibodies and serum/plasma circulating VEGF levels were detected in 39 and 38 patients by ELI- SA, respectively. RESULTS: A total of 69% of patients were positive for circulating IgG antibodies against H pylori. cagA-positive H pylori strains were found in 41% of gastric patients. vacA was found in 50% of patients; s1 strains were more highly expressed among vacA-positive patients. The presence of the s1 strain was signifi cantly associ- ated with cagA (P = 0.0001). MVD was signifi cantly cor- related with both tumor VEGF expression (r = 0.361, P = 0.009) and serum VEGF levels (r = -0.347, P = 0.041).Conversely, neither VEGF-R1 expression nor MVD was related to p53 expression. However, H pylori was not related to any angiogenic markers except for the plasma VEGF level (P = 0.026). CONCLUSION: H pylori antigen is related to higher plasma VEGF levels, but not to angiogenic character- istics. It can be hypothesized that the toxic effects of H pylori on angiogenesis occurs in early preclinical dis- ease phase or in long-lasting aggressive infections, but only when high H pylori IgG levels are persistent. | Anita Mangia Annalisa Chiriatti Girolamo Ranieri Ines Abbate Maria Coviello Giovanni Simone Francesco Alfredo Zito Severino Montemurro Antonello Rucci Alfredo Di Leo Stefania Tommasi Pasquale Berloco Jian Ming Xu Angelo Paradiso | 2006 | World Journal of Gastroenterology2006,12,34: | 5 |
| 2 | Search for light vector boson production in e + e ? → μ + μ ? γ interactions with the KLOE experiment显示文摘 | D. Babusci I. Balwierz-Pytko G. Bencivenni C. Bloise F. Bossi P. Branchini A. Budano L. Caldeira Balkest?hl F. Ceradini P. Ciambrone F. Curciarello E. Czerwiński E. Danè V. De Leo E. De Lucia G. De Robertis A. De Santis P. De Simone A. Di Cicco A. Di Dome | 2014 | Physics Letters B2014,,: | 3 |
| 3 | Agri-environmental policies in the EU and United States: A comparison显示文摘 | Kathy Baylis Stephen Peplow Gordon Rausser Leo Simon | 2007 | Ecological Economics2007,,4: | 3 |
| 4 | Adjustable white-light emission from a photo-structured micro-OLED array显示文摘White organic light-emitting diodes(OLEDs)are promising candidates for future solid-state lighting applications and backplane illumination in large-area displays.One very specific feature of OLEDs,which is currently gaining momentum,is that they can enable tunable white light emission.This feature is conventionally realized either through the vertical stacking of independent OLEDs emitting different colors or in lateral arrangement of OLEDs.The vertical design is optically difficult to optimize and often results in efficiency compromises between the units.In contrast,the lateral concept introduces severe area losses to dark regions between the subunits,which requires a significantly larger overall device area to achieve equal brightness.Here we demonstrate a color-tunable,two-color OLED device realized by side-by-side alignment of yellow and blue p-i-n OLEDs structured down to 20μm by a simple and up-scalable orthogonal photolithography technique.This layout eliminates the problems of conventional lateral approaches by utilizing all area for light emission.The corresponding emission of the photo-patterned two-unit OLED can be tuned over a wide range from yellow to white to blue colors.The independent control of the different units allows the desired overall spectrum to be set at any given brightness level.Operated as a white light source,the microstructured OLED reaches a luminous efficacy of 13 lm W^(−1) at 1000 cd m^(−2) without an additional light outcoupling enhancement and reaches a color rendering index of 68 when operated near the color point E.Finally,we demonstrate an improved device lifetime by means of size variation of the subunits. | Simonas Krotkus Daniel Kasemann Simone Lenk Karl Leo Sebastian Reineke | 2016 | Light(Science & Applications)2016,5,1: | 2 |
| 5 | Lymph Node Involvement in Gastric Cancer for Different Tumor Sites and T Stage显示文摘 | Alberto Leo Daniele Marrelli Franco Roviello Marco Bernini AnnaMaria Minicozzi Simone Giacopuzzi Corrado Pedrazzani Luca Gian Baiocchi Giovanni Manzoni | 2007 | Journal of Gastrointestinal Surgery2007,,9: | 1 |
| 6 | Search for dark Higgsstrahlung in e + e ? → μ + μ ? and missing energy events with the KLOE experiment显示文摘 | A. Anastasi D. Babusci G. Bencivenni M. Berlowski C. Bloise F. Bossi P. Branchini A. Budano L. Caldeira Balkest?hl B. Cao F. Ceradini P. Ciambrone F. Curciarello E. Czerwiński G. D’Agostini E. Danè V. De Leo E. De Lucia A. De Santis P. De Simone A. Di Cic | 2015 | Physics Letters B2015,,: | 1 |
| 7 | Color-stable, ITO-free white organic light-emitting diodes with enhanced efficiency using solution-processed transparent electrodes and optical outcoupling layers显示文摘 | Hong-Wei Chang Yong Hyun Kim Jonghee Lee Simone Hofmann Bj?rn Lüssem Lars Müller-Meskamp Malte C. Gather Karl Leo Chung-Chih Wu | 2014 | Organic Electronics2014,,5: | 1 |
| 8 | Limit on the production of a low-mass vector boson in e + e ? → U γ , U → e + e ? with the KLOE experiment显示文摘 | A. Anastasi D. Babusci G. Bencivenni M. Berlowski C. Bloise F. Bossi P. Branchini A. Budano L. Caldeira Balkest?hl B. Cao F. Ceradini P. Ciambrone F. Curciarello E. Czerwiński G. D’Agostini E. Danè V. De Leo E. De Lucia A. De Santis P. De Simone A. Di Cic | 2015 | Physics Letters B2015,,: | 1 |
| 9 | Hydraulic fractures: How far can they go?显示文摘 | Richard J. Davies Simon A. Mathias Jennifer Moss Steinar Hustoft Leo Newport | 2012 | Marine and Petroleum Geology2012,,1: | 1 |
| 10 | Gastric Stump Cancer After Distal Gastrectomy for Benign Disease: Clinicopathological Features and Surgical Outcomes显示文摘 | Alberto Di Leo Corrado Pedrazzani Maria Bencivenga Arianna Coniglio Fausto Rosa Paolo Morgani Daniele Marrelli Alberto Marchet Luca Cozzaglio Simone Giacopuzzi Guido Alberto Massimo Tiberio Giovanni Battista Doglietto Giovanni Vittimberga Franco Roviello | 2014 | Annals of Surgical Oncology2014,,8: | 1 |
| 11 | Agri-environmental Policies in the EU and United States : A Comparison 显示文摘 | Baylis Kathy Stephen Peplow Gordon Rausser and Leo Simon | 2007 | Ecological Economics2007,,7: | 1 |
| 12 | Carbon Monoxide Induces Cytoprotection in Rat Orthotopic Lung Transplantation via Anti-Inflammatory and Anti-Apoptotic Effects显示文摘 | Ruiping Song Masatoshi Kubo Danielle Morse Zhihong Zhou Xuchen Zhang James H. Dauber James Fabisiak Sean M. Alber Simon C. Watkins Brian S. Zuckerbraun Leo E. Otterbein Wen Ning Tim D. Oury Patty J. Lee Kenneth R. McCurry Augustine M.K. Choi | 2003 | The American Journal of Pathology2003,,1: | 1 |
| 13 | The “mitochondrial stress responses”: the “Dr. Jekyll and Mr. Hyde” of neuronal disorders显示文摘Neuronal disorders are associated with a profound loss of mitochondrial functions caused by various stress conditions,such as oxidative and metabolic stress,protein folding or import defects,and mitochondrial DNA alteration.Cells engage in different coordinated responses to safeguard mitochondrial homeostasis.In this review,we will explore the contribution of mitochondrial stress responses that are activated by the organelle to perceive these dangerous conditions,keep them under control and rescue the physiological condition of nervous cells.In the sections to come,particular attention will be dedicated to analyzing how compensatory mitochondrial hyperfusion,mitophagy,mitochondrial unfolding protein response,and apoptosis impact human neuronal diseases.Finally,we will discuss the relevance of the new concept:the“mito-inflammation”,a mitochondria-mediated inflammatory response that is recently found to cover a relevant role in the pathogenesis of diverse inflammatory-related diseases,including neuronal disorders. | Simone Patergnani Giampaolo Morciano Marianna Carinci Sara Leo Paolo Pinton Alessandro Rimessi | 2022 | Neural Regeneration Research2022,17,12: | 1 |
| 14 | Initial experience with wireless capsule enteroscopy in the diagnosis and management of inflammatory bowel disease显示文摘 | William S Mow Simon K Lo Stephan R Targan Marla C Dubinsky Leo Treyzon Maria T Abreu-martin Konstantinos A Papadakis Eric A Vasiliauskas | 2004 | Clinical Gastroenterology and Hepatology2004,,1: | 1 |
| 15 | Social cognition as the default mode of cognizing and its putative relationship to the 'default system' of the brain 显示文摘 | LEO S SIMON B | 2008 | Consciousness and Cognition2008,17,2: | 1 |
| 16 | A comparison of flow field structures of two tri-leaflet polymeric heart valves显示文摘 | Leo HL Simon H Carberry J | 2005 | Ann Biomed Eng2005,33,4: | 1 |
| 17 | Follow-Up After Gastrectomy for Cancer: An Appraisal of the Italian Research Group for Gastric Cancer显示文摘 | Gian Luca Baiocchi Daniele Marrelli Giuseppe Verlato Paolo Morgagni Simone Giacopuzzi Arianna Coniglio Alberto Marchet Fausto Rosa Michela Giulii Capponi Alberto Leo Luca Saragoni Luca Ansaloni Fabio Pacelli Donato Nitti Domenico D’Ugo Franco Roviello Gui | 2014 | Annals of Surgical Oncology2014,,6: | 1 |
| 18 | Generalized B-cell non Hodgkin lymphoma in association with leukocytoclastic vasculitis and disseminated intravascular coagulation 显示文摘 | Carla Cardinali Simone Santini Angelo di Leo | 2006 | Dermatology Online Journal2006,12,3: | 1 |
| 19 | Agri environmental policies in the EU and United States:a com parison显示文摘 | Kathy Baylis Stephen Peplow Gordon Rausser Leo Simon | 2008 | Ecological Economic2008,65,5: | 1 |
| 20 | Minds at rest? Social cognition as the default mode of cognizing and its putative relationship to the “default system” of the brain显示文摘 | Leo Schilbach Simon B. Eickhoff Anna Rotarska-Jagiela Gereon R. Fink Kai Vogeley | 2008 | Consciousness and Cognition2008,,2: | 1 |