|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F显示文摘 | Moritz Leppkes Christoph Becker Ivaylo I. Ivanov Sebastian Hirth Stefan Wirtz Clemens Neufert Sandrine Pouly Andrew J. Murphy David M. Valenzuela George D. Yancopoulos Burkhard Becher Dan R. Littman Markus F. Neurath | 2009 | Gastroenterology2009，，1： | 2 |
| 2 | STAT3 links IL-22 sig- naling in intestinal epithelial cells to mucosal wound healing显示文摘 | Pickert G Neufert C Leppkes M | 2009 | J Exp Med2009，206，7： | 1 |
| 3 | Scientific Registry of Transplant Recipients:collecting,analyzing,andreporting data on transplantation in the United States显示文摘 | Leppke S Leighton T Zaun D | 2013 | Transplant Rev(Orlando)2013，27，2： | 1 |
| 4 | Retrograde inspection vs standard forward view for the detection of colorectal adenomas during colonoscopy: A back-to-back randomized clinical trial显示文摘BACKGROUND The adenoma detection rate(ADR)is inversely associated with the incidence of interval colorectal cancer and serves as a benchmark quality criterion during screening colonoscopy.However,adenoma miss rates reach up to 26%and studies have shown that a second inspection of the right colon in retroflected view(RFV)can increase ADR.AIM To assess whether inspection of the whole colon in RFV compared to standard forward view(SFV)can increase ADR.METHODS Patients presenting for screening or surveillance colonoscopy were invited to participate in this randomized controlled trial and randomized into two arms.In RFV arm colonoscopy was initially performed with SFV,followed by a second inspection of the whole colon in RFV.In the SFV arm first withdrawal was performed with SFV,followed by a second inspection of the whole colon again with SFV.Number,size and morphology of polyps found during first and second inspection in each colonic segment were recorded and all polyps were removed and sent for histopathology in separate containers.RESULTS Two hundred and five patients were randomly assigned to the RFV(n=101)and SFV(n=104)arm.In the RFV arm,both polyp detection rate(PDR)and ADR were increased under second inspection in RFV(PDR 1st SFV:39.8%,PDR 2nd RFV:46.6%;ADR 1st SFV:35.2%,ADR 2nd RFV:42%).Likewise,in the SFV arm,PDR and ADR were increased under second inspection(PDR 1st SFV:37.5%,PDR 2nd SFV:46.6%;ADR 1st SFV:34.1%,ADR 2nd SFV:44.3%)with no significant differences in ADR and PDR between the SFV and RFV arm.Mean number of adenomas per patient(APP)was increased in the RFV and SFV(APP RFV arm:1st SFV:1.71;2nd RFV:2.38;APP SFV arm:1st SFV:1.83,2nd SFV:2.2).The majority of adenomas additionally found during second inspection in RFV or in SFV were located in the transverse and left-sided colon and were>5 mm in size.CONCLUSION Second inspection of the whole colon leads to increased adenoma detection with no differences between SFV and RFV.Hence,increased detection is most likely a feature of the second inspection itself but not of the inspection mode. | Timo Rath Lukas Pfeifer Clemens Neufert Andreas Kremer Moritz Leppkes Arthur Hoffman Markus F Neurath Steffen Zopf | 2020 | World Journal of Gastroenterology2020，26，16： | 1 |
| 5 | Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK显示文摘 | Neufert Clemens Becker Christoph Türeci ?zlem Waldner Maximilian J Backert Ingo FIoh Katharina Atreya lmke Leppkes Moritz Jefremow Andre Vieth Michael Schneider-Stock Regine Klinger Patricia Greten Florian R Threadgill David W Sahin Ugur Ne | 2013 | Journal of Clinical Investigation2013，，4： | 1 |
| 6 | STAT3 links IL - 22 sig- naling in intestinal epithelial cells to mucosal wound healing显示文摘 | Pickert G Neufert C Leppkes M | 2009 | J Exp Med2009，206，7： | 1 |
| 7 | STAT3links IL-22signaling in intestinal epithelial cells to mucosal wound healing显示文摘 | Pickert G Neufert C Leppkes M | 2009 | J Exp Med2009，206，7： | 1 |
| 8 | STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing显示文摘 | Pickert G Neufert C Leppkes M | 2009 | J Exp Med2009，206，7： | 1 |
| 9 | RORgamma-expressing Th17cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F显示文摘 | Leppkes M Becker C Ivanov II | 2009 | Gastroenterology2009，136，1： | 1 |
| 10 | STAT3 links IL - 22 signaling in intestinal epithelial cells to mucosal wound healing 显示文摘 | PICKERT G NEUFERT C LEPPKES M | 2009 | J Exp Med2009，206，7： | 1 |
| 11 | Pleiotropie functions of TNF-a in the regulation of the intestinal epithelial response to in- flammation显示文摘 | Leppkes M Roulis M Neurath MF | 2014 | Int Immunol2014，26，9： | 1 |
| 12 | RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redun- dant effects of IL-17A and IL-17F显示文摘 | Leppkes M Becker C Ivanov Ⅱ | 2009 | Gastroenterology2009，136，1： | 1 |
| 13 | RORg-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F显示文摘 | Leppkes M Becker C Ivanov II | 2009 | Gastroenterology2009，136，1： | 1 |
| 14 | STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing显示文摘 | Pickert G Neufert C Leppkes M | 2009 | J Exp Med2009，206，7： | 1 |
| 15 | STAT3 links IL 22 signaling in intestinal epitheli al cells to mucosal wound healing显示文摘 | Pickert G Neufert C Leppkes M Zheng Y Wittkopf N Warn tien M | 2009 | J Exp Med2009，206，： | 1 |
| 16 | STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing显示文摘 | Pickert G Neufert C Leppkes M et at | 2009 | J Exp Meal2009，206，7： | 1 |
| 17 | STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing显示文摘 | Pickert G Neufert C Leppkes M | 2009 | J ExpMed2009，206，7： | 1 |
| 18 | ROR gamma-ex- pressing Thl7 cells induce murine chronic intestinal in- flammation via redundant effects of IL-17A and IL-17F 显示文摘 | Leppkes M Becker C Ivanov II | 2009 | Gastroenterology2009，136，1： | 1 |
| 19 | STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing显示文摘 | Pickert G Neufert C Leppkes M | 2009 | J Exp Med2009，206，7： | 1 |
| 20 | RORqamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F显示文摘 | LEPPKES M BECKER C IVANOV I | 2009 | Gastroenterology2009，136，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员