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| 1 | 我国农村居民的红细胞脂肪酸、血浆脂质与心血管疾病显示文摘对我国49个县的心血管疾病(CVD,包括冠心病、高血压心脏病和脑卒中)死亡率和4900例35~64岁成年男女的膳食进行了调查,并测定了血浆脂质[总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和甘油三酸酯(TG)]的含量,结果指出:1.和西方国家人群比较,我国农民血浆TC、TG、HDL-C和依此计算而得的LDL-C水平较低,而HDL-C/TC比值较高,CVD死亡率也较西方国家的为低。2.在TC、LDL-C与CVD死亡率之间无相关,但在红细胞油酸水平与CVD死亡率间有显著负相关。3.红细胞油酸水平与血浆TC含量间无相关,而与红细胞花生四烯酸水平呈显著负相关。指出油酸对CVD死亡率的影响有可能是通过另一条途径,即减低血小板的聚集作用。4.我国的CVD死亡率呈现明显的地区性分布,即南方低于北方。其分布与红细胞油酸含量,及大米摄取量的地区性分布呈明显的负关系。5.为解释CVD死亡率与红细胞油酸的负关系,本文提出了油酸可能置换了血小板膜磷脂中多不饱和脂肪酸的设想,但对大米保护CVD的作用则尚需有更多的调查和研究数据才能确证之。 | 范文洵 Parker R Parpia B 屈荫生 Cassano P Crawford M Leyton J 田巧珍 黎均耀 陈君石 Campbell C | 1992 | 营养学报1992，14，1： | 15 |
| 2 | Science Letters:Quantification of Helicobacter pylori levels in soil samples from public playgrounds in Spain显示文摘Helicobacter pylori are ubiquitous Gram-negative bacteria with a high estimated level of infection in the world populations, but a majority of the infected persons are asymptomatic. This pathogen has been classified by the World Health Organization as a class I carcinogen and recognized as the causal agent of most peptic ulcers and chronic gastritis that might lead to stomach cancer. Although not all the transmission pathways of these bacteria into humans have been properly identified, enough data have suggested that the oral-oral or fecal-oral ones are the main infection routes. Helicobacter pylori have been detected in non-treated water and in drinking water, which suggested that water might be an important infection source. As childhood is the critical period of infection, the aim of the present work was to examine the presence of Helicobacter pylori in soil samples from public playing areas of Spanish parks. | Leonardo Martín PéREZ Francesc CODONY Daniela LóPEZ LEYTON Mariana FITTIPALDI Bárbara ADRADOS Jordi MORATó | 2010 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2010，11，1： | 2 |
| 3 | Recombinant mouse ZP3 inhibitssperm binding and induces the acrosome reaction 显示文摘 | Beebe SJ Leyton L Burks D | 1992 | Dev Biol1992，151，： | 2 |
| 4 | Lipoxygenase inhibitors prevent lung carcinogenesis and inhibit non-small cell lung cancer growth显示文摘 | Moody T W Leyton J Martinez A | 1998 | Exp Lung Res1998，24，4： | 1 |
| 5 | Subtypes of progressive aphasia:application of the international consensus criteria and validation using B-amyloid imaging显示文摘 | Leyton CE Villemagne VL Savage S | 2011 | Brain2011，134，10： | 1 |
| 6 | Indomethacin reduces lung adenoma number in A/J mice 显示文摘 | Moody TW Leyton J Zakowicz H | 2001 | Anticancer Res2001，21，3： | 1 |
| 7 | Determination of opiates in whole blood and vitreous humor: a study of the matrix effect and an experimental design to optimizeconditions for the enzymatic hydroly- sis of glucuronides 显示文摘 | Sanches LR Seulin SC Leyton V | 2012 | J Anal ToxicoL2012，36，： | 1 |
| 8 | Effectiveness of a dietary and physical activity intervention to prevent obesity in school age children显示文摘 | Kain J Uauy R Leyton B | | 0，，01： | 1 |
| 9 | Reflection-absorption IR and surface-enhanced IR spectroscopy of tetracarboethoxy t -butyl -calix arene,as a host molecule with potential applications in sensor devices显示文摘 | Leyton P Domingo C Sanchez-Cortes S | 2007 | Vibrational Spectroscopy2007，43，2： | 1 |
| 10 | Early detection of tumor response to chemotherapy by 3′-deoxy-3′-[18 F]fluorothymidine positron emission tomography:the effect of cisplatin on a fibrosarcoma tumor model in vivo显示文摘 | Leyton J Latigo JR Perumal M | | 0，，： | 1 |
| 11 | BMP type II recep- tors have redundant roles in the regulation of hepatic hepcidin gene expression and iron metabolism 显示文摘 | Mayeur C Leyton PA Kolodziej SA | 2014 | Blood2014，124，13： | 1 |
| 12 | Analysis of bovine immunoglobulin G in milk,colostrum and dietary supplements:a review显示文摘 | Leyton W Gapper David E J Copestake Don E Otter Harvey E Indyk | 2007 | Anal Bioanal Chem2007，389，： | 1 |
| 13 | Caveolins, caveolae, and lipid rafts in cellular transport, signaling, and disease 显示文摘 | Quest AF Leyton L Parraga M | 2004 | Biochem Cell Biol2004，82，1： | 1 |
| 14 | The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6 显示文摘 | Mayeur C Lohmeyer LK Leyton P | 2014 | Blood2014，123，14： | 1 |
| 15 | Thymosin alpha 1 is chemopreventive for lung adenoma formation in A/J mice显示文摘 | Moody TW Leyton J Zia F | 2000 | Cancer letter2000，155，2： | 1 |
| 16 | Amphetamine-induced Increases in extrace-llular dopamine,drug wanting,and novelty seeking:a PET/ raclopride study in healthy men显示文摘 | Leyton M BoileauI Benkelf at C | 2002 | Neuropsychopharmacology2002，27，： | 1 |
| 17 | Noninvasive imaging of cell proliferation following mitogenic extracellular kinase inhibition by PD0325901显示文摘 | Leyton J Smith G Lees M | | 0，，9： | 1 |
| 18 | Differential oxidation of saturated fatty acids in vivo in the rat 显示文摘 | Leyton J Drury P J Crawford M A | 1987 | Brit J Nutr1987，57，： | 1 |
| 19 | Dopamine precursor depletion impairs structure and efficiency of resting state brain functional networks显示文摘 | ARBONELL F NAGANO-SAITO A LEYTON M | 2014 | Neuropharmacology2014，84，： | 1 |
| 20 | An increase intraovarian synthesis of nerve growth factor and its low affinity receptor is a principal component of steroid-induce polycystic ovary in the rat显示文摘 | Lara HE Dissen GA Leyton V | 2000 | Endocrinology2000，141，： | 1 |
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