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| 1 | 杏仁核-海马环路参与抑郁症的发病机制显示文摘慢性应激常可引发抑郁症。临床资料显示,抑郁症病人的腹侧海马CA1区(vCA1)n体积减小。vCA1是否参与抑郁症的发病?vCA1通过什么环路起作用?其分子机制如何?是本文要回答的科学问题。研究者利用慢性不可预见性温和应激(CUMS),构建小鼠抑郁症模型。主要结果如下:(1)与对照组相比,CUMS组vCA1中表达c-Fos的兴奋性神经元的比例降低。采用化学遗传学方法激活vCA1内兴奋性神经元,可明显缓解抑郁样行为。因此,海马vCA1内兴奋性神经元的活性降低,介导抑郁症的发生。 | 刘风雨(译) Ma H Li CY Wang JP | 2021 | 中国疼痛医学杂志2021，27，2： | 9 |
| 2 | The compression of IR spectra by using wavelet neural network显示文摘IR spectra play an important role in determining the structure of compounds qualitatively andquantitatively.In general a great number of data are required to exactly show the features ofthe compounds.Regarding various compounds,there are massive IR spectra.With the basicfeatures of IR spectra being reserved,it is important to compress IR spectra for improving thestorage,index and process of IR spectra.The wavelet neural network(WNN)is a newneural network model based on wavelet analysis.However,its introduction and applica-tion in chemistry have not been reported.In this note,WNN is applied to the compression ofthe IR spectra of polystyrene.The results show that the original spectra can be | Liu, W Li, JP Xiong, JH Pan, ZX Zhang, MS | 1997 | Chinese Science Bulletin1997，42，10： | 8 |
| 3 | Zircon U-Pb dating of Shuiquangou alkaline complex intrusives, northwestern Hebei Province显示文摘SUPER large gold deposits related to alkaline intrusions have been found in America,Canada,Australia,Papua New Guinea and elsewhere.Dongping gold deposit with superlarge potentialhas also been found in Shuiquangou alkaline complex intrusions,northwestern Hebei Province,China.One of the keys to resolving the possible genetic relationship between gold deposits andore-host alkaline intrusions is to determine their formation ages.This note dates the Shuiquan-gou intrusions with zircon U-Pb method. | Mo, CH Liang, HY Wang, XZ Cheng, JP Li, HM | 1997 | Chinese Science Bulletin1997，42，9： | 6 |
| 4 | High-level expression of human calmodulin in E.coli and its effects on cell proliferation显示文摘INTRODUCTIONCalmodulin(CaM),widely distributed in almost alleukaryotic cells,is a major intracellular calcium receptorresponsible for mediating the Ca2+ signal to a multitude ofdifferent enzyme systems and is thought to play a vital rolein the regulation of cell proliferative cycle.Recently, | Li XJ Wu JG Si JL Guo DW Xu JP | 2000 | World Journal of Gastroenterology2000，6，4： | 3 |
| 5 | Effect of endoplasmic reticulum stress in VEGF-induced neuroprotection显示文摘 | Yang JP Liu H J Li Y | 2009 | J Invest Surg2009，22，： | 1 |
| 6 | Apoptosis in the ocular lens: role in development and pathogenesis 显示文摘 | Yan Q Liu JP Li DW | 2006 | Differentiation2006，74，5： | 1 |
| 7 | Evaluation of longitudinal ventricular function with tissue Doppler echocardiography in children treated with an- thracyclines显示文摘 | Stapleton GE Stapleton SL Martinez A Ayres NA Kovalchin JP Bezold LI | 2007 | J Am Soc Echocardiogr2007，20，5： | 1 |
| 8 | Substrate specificity of heparanases from human hepatoma and platelets 显示文摘 | Pikas DS Li JP Vlodavsky I | 1998 | J Biol Chem1998，273，18： | 1 |
| 9 | Catalytic pomain of PRL-3 plays an essential role in tumor metastasis显示文摘 | Guo K Li J Tang JP | 2004 | Cancer Biol Ther2004，3，： | 1 |
| 10 | Inhibiting epi-dermal growth factor receptor attenuates reactive as-trogliosis and improves ftinctional outcome after spinalcord injury in rats 显示文摘 | Li ZW Tang RH Zhang JP | 2011 | Neurochem Int2011，58，： | 1 |
| 11 | Mental Health and Social Support Among HW - Positive Injection Drug Users and Their Caregivers in China显示文摘 | Greene MC Zhang JP Li JP | 2013 | AIDS Behav2013，17，5： | 1 |
| 12 | Reducing personal exposure to partic- ulate air pollution improves cardiovascular health in patients with coro- nary heart disease显示文摘 | Langrish JP Li X Wang S | 2012 | Environ Health Perspect2012，120，3： | 1 |
| 13 | Fate of Escherichiacoli O157:H7,Listeria monocytogenes,and Salmonella on fresh-cut celery显示文摘 | Vandamma JP Li D Harris LJ | 2013 | Food Microbiology2013，34，： | 1 |
| 14 | Decreased tobacco-specific nitrosamines by microbial treatment with Bacillus amyloliquefaciens DA9 during the Air-Curing process of burley tobacco 显示文摘 | Wei XT Deng XW Cai DB Ji ZX Wang CJ Yu J Li JP and Chen SW | 2014 | J Agric Food Chem2014，62，12： | 1 |
| 15 | The prevalence of primary glaucoma in mainland China : a system- atic review and meta-analysis显示文摘 | CHENG JW CHENG SWjMA XY CAI JP LI Y WEI RL | 2013 | J Glaucoma2013，22，4： | 1 |
| 16 | Cyclin B1 proteolysis via p38 MAPK signaling participates in G2 checkpoint elicited by arsenite显示文摘 | Li JP Yang JL | 2007 | J Cell Physiol2007，212，2： | 1 |
| 17 | Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 of Rb oligonucleotides 显示文摘 | Hatzfeld J Li ML Brown EL Sookdeo H Levesque JP O′Toole T | 1991 | JExp Med1991，174，4： | 1 |
| 18 | Telomerase activation causes vascular smooth muscle cell proliferation in genetic hypertension显示文摘 | Cao Y Li H Mu FT Ebisui O Funder JW Liu JP | 2002 | FASEB2002，16，1： | 1 |
| 19 | CD20-mediated apoptosis: Signaling through lipid rafts显示文摘 | Deans JP Li H Polyak MJ | 2002 | Immunology2002，107，2： | 1 |
| 20 | Biomechanical stimulation of osteoblast gene expression requires phosphorylation of the RUNX2 transcription factor显示文摘 | Li Y Ge C Long JP | 2012 | J Bone Miner Res2012，27，6： | 1 |
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