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1福建省社区产后访视质量调查研究显示文摘目的:研究社区产后访视服务现状,提高社区护理质量,促进母婴健康.方法:定量与定性研究相结合,定量研究随机抽取福州市5区内产后42 d左右的产妇776例问卷调查,定性研究采用专题小组讨论和半结构性访谈.产妇12人参加专题讨论,半结构性访谈9人.结果:产后访视率为62.9%,按3~4次标准进行的仅4.3%~48.2%.社区产后访视内容中,询问母子一般情况达98.4%;对产妇及新生儿体检的内容欠缺多;进行母乳喂养指导为94.7%;认为对产妇心理情绪状况'关心与非常关心'的占28.7%,对预防产后抑郁症的保健建议率占9.9%;对社区产后访视满意率不高为33.6%.结论:与产后访视的次数和内容的标准对照,实际操作中的偏差是由于缺乏规范化的管理,因此今后既要加快产后访视人员刘产褥期护理与保健知识的更新,拓展提供保健知识的内容,又要在现有社区产后访视过程中,加强规范化管理,区级妇幼保健机构应对辖区内的社区产妇的产后访视工作实行面对面的质量评估问卷,达到规范化管理的目的,并采取针对性措施提高产后访视中的护理与保健质量.陈起燕 陈烈平 张荣莲 叶宝凤 翁云钦 卓秀云 Yu liana Da tu Bua 2005中国妇幼保健2005,20,5:33
2Transcriptome and Metabolic Profiling Provides Insigh into Betalain Biosynthesis and Evolution in Mirabilis jalapa显示文摘Guy Polturak Uwe Heinig Noam Grossman Maor Battat Dena Leshkowitz Sergey Malitsky liana Rogachev~ and Asaph Aharoni 2018Molecular Plant2018,11,1:10
3Neoadjuvant vs adjuvant pelvic radiotherapy for locally advanced rectal cancer: Which is superior?显示文摘The treatment of locally advanced rectal cancer including timing and dosage of radiotherapy, degree of sphincter preservation with neoadjuvant radiotherapy, and short and long term effects of radiotherapy are controversial topics. The MEDLINE, Cochrane Library databases, and meeting proceedings from the American Society of Clinical Oncology, were searched for reports of randomized controlled trials and meta-analyses comparing neoadjuvant and adjuvant radiotherapy with surgery to surgery alone for rectal cancer. Neoadjuvant radiotherapy shows superior results in terms of local control compared to adjuvant radiotherapy. Neither adjuvant or neoadjuvant radiotherapy impacts overall survival. Short course versus long course neoadjuvant radiotherapy remains controversial. There is insufficient data to conclude that neoadjuvant therapy improves rates of sphincter preserving surgery. Radiation significantly impacts anorectal and sexual function and includes both acute and long term toxicity. Data demonstrate that neoadjuvant radiation causes less toxicity compared to adjuvant radiotherapy, and specifically short course neoadjuvant radiation results in less toxicity than long course neoadjuvant radiation. Neoadjuvant radiotherapy is the preferred modality for administering radiation in locally advanced rectal cancer. There are significant side effects from radiation, including anorectal and sexual dysfunction, which may be less with short course neoadjuvant radiation.Sarah Popek Vassiliki Liana Tsikitis 2011World Journal of Gastroenterology2011,17,7:10
4Frequency control of future power systems: reviewing and evaluating challenges and new control methods显示文摘Integration of more renewable energy resources introduces a challenge in frequency control of future power systems.This paper reviews and evaluates the possible challenges and the new control methods of frequency in future power systems.Different types of loads and distributed energy resources(DERs) are reviewed.A model representation of a population of the water heater devices for the demand side frequency response is considered.A model representation of a population of battery energy storage system(BESS)-based DERs such as smart electric vehicles(EVs) charging, large-scale BESSs, and residential and non-residential BESSs, are highlighted.The simplified Great Britain power system and the 14-machine South-East Australian power system were used to demonstrate the effectiveness of the new methods in controlling power system frequency following a disturbance.These new methods are effective in recovering the fallen frequency response and present a great potential in controlling the frequency in future power systems.Zeyad Assi OBAID Liana M.CIPCIGAN Lahieb ABRAHIM Mazin T.MUHSSIN 2019Journal of Modern Power Systems and Clean Energy2019,7,1:8
5The influence of the crystalline nature of nano-metal oxides on their antibacterial and toxicity properties显示文摘nano 金属氧化物的抗菌剂性质(ZnO, CuO ) 基于反应的氧种类(ROS ) 的形成。这个工作表明这些 nano 金属氧化物的抗菌剂性质强烈依赖于他们的水晶的结构。nanooxides 的抗菌剂活动对通常引起医院的感染的细菌的四种类型被测试。sonochemical 方法在纺织品上为 nanooxides 而且到他们的涂层的合成被使用不仅。与商业、 sonochemically 准备的 nano 金属氧化物涂的纺织品的抗菌剂性质被评估并且比较。毒性在人的肺房间和两栖动物胚胎上被评估,作为为吸入和水的毒物学的代表性的模型。sonochemically 准备的金属 nanooxides 比有一样的粒子尺寸范围的商业地可得到的金属氧化物是更好的抗菌剂。有更多的缺点和更少的组织结构的雏晶是更多,这被发现有毒。ROS 的形成被电子纺纱学习为两个的回声(ESR ) 大小 sonochemically 准备了并且 ZnO/CuO nanoparticles 的商业样品。激进的种类的生产的重要增加在更有缺点的、 sonochemically 准备的样品被发现,作为与商业的相比。因为 nanoparticle 缺点的调整影响了他们的毒性,设计更安全的 nano 抗菌剂的可能性被显示。liana Perelshtein Anat Lipovsky Nina Perkas Aharon Gedanken Elisa Moschini Paride Mantecca 2015Nano Research2015,8,2:8
6A state-of-the-art review of the fabrication and characteristics of titanium and its alloys for biomedical applications显示文摘Commercially pure titanium and titanium alloys have been among the most commonly used materials for biomedical applications since the 1950 s.Due to the excellent mechanical tribological properties,corrosion resistance,biocompatibility,and antibacterial properties of titanium,it is getting much attention as a biomaterial for implants.Furthermore,titanium promotes osseointegration without any additional adhesives by physically bonding with the living bone at the implant site.These properties are crucial for producing high-strength metallic alloys for biomedical applications.Titanium alloys are manufactured into the three types ofα,β,andα+β.The scientific and clinical understanding of titanium and its potential applications,especially in the biomedical field,are still in the early stages.This review aims to establish a credible platform for the current and future roles of titanium in biomedicine.We first explore the developmental history of titanium.Then,we review the recent advancement of the utility of titanium in diverse biomedical areas,its functional properties,mechanisms of biocompatibility,host tissue responses,and various relevant antimicrobial strategies.Future research will be directed toward advanced manufacturing technologies,such as powder-based additive manufacturing,electron beam melting and laser melting deposition,as well as analyzing the effects of alloying elements on the biocompatibility,corrosion resistance,and mechanical properties of titanium.Moreover,the role of titania nanotubes in regenerative medicine and nanomedicine applications,such as localized drug delivery system,immunomodulatory agents,antibacterial agents,and hemocompatibility,is investigated,and the paper concludes with the future outlook of titanium alloys as biomaterials.Masoud Sarraf Erfan Rezvani Ghomi Saeid Alipour Seeram Ramakrishna Nazatul Liana Sukiman 2022Bio-Design and Manufacturing2022,5,2:8
7不同脂肪酶酶解奶油制备奶味香基的研究显示文摘选用Hansen calf lipase、Amano lipase A6、Lipozyme RM IM 3种脂肪酶对无水奶油进行适度酶解制备奶味香基。采用气相色谱分析了酶解奶油中游离脂肪酸组成,结合顶空固相微萃取-气相色谱质谱联用技术对酶解奶油中的挥发性风味成分进行研究,并通过感官评价对酶解奶油进行风味剖面分析并对烘焙产品偏好性评定。结果表明:3种脂肪酶选择性酶解产生中短链脂肪酸的能力均较强,其中动物来源的Hansen calf lipase对中短链脂肪酸的选择性酶解能力最高,酶解奶油中短链脂肪酸相对含量为42.9%,且该酶解奶油和烘焙产品具有令人愉悦的奶味和干酪味;3种酶解奶油中的挥发性风味成分主要为脂肪酸、醛类、酮类、内酯类物质。张宁 赵金利 CYRIL Suseno 滕英来 汪勇 李爱军 LIANA Veronika Yapriadi 2015中国油脂2015,40,4:6
8Cancer and age related colonic crypt deficiencies in cytochrome c oxidase Ⅰ显示文摘AIM: To investigate whether defi ciency of expressionof cytochrome c oxidase I (CcOI) in colonic crypts is associated with colon cancer.METHODS: The pattern and level of expression of CcOI in non-neoplastic colonic crypts,and in dysplastic tissues,was assessed using standard immunohis-tochemical methods.Biopsies were obtained from individuals undergoing colonoscopies for screening purposes or for a medically indicated reason.Tissue samples were also obtained from surgical colonic resections.Samples from resections were taken from colonic mucosa 1 and 10 cm from tumors and from the tumors themselves.Samples were evaluated for frequency of crypts with reduced or absent expression of CcOI.In most crypts the loss was apparent throughout the entire crypt,while in a small minority the loss was segmental.The strong immunoreactivity using this monoclonal antibody makes the scoring unambiguous.The percent of crypts with reduced or absent expression of CcOI or (infrequent) segmented loss of expression was then calculated.Data analyses were performed using SPSS statistical package 17.0.RESULTS: The average frequency of CcOI deficient crypts (CcOI-DC) is low in individuals between 20 and 39 years of age,with 0.48% ± 0.40% CcOI-DC for women and 1.80% ± 0.35% for men.CcOI-DC increases after age 40 years,so that between the ages of 40 and 44 years the average frequency of CcOI- DC goes up to 5.89% ± 0.84% in women and 2.15% ± 1.27% in men.By 80-84 years of age,the average frequency of CcOI-DC goes up in women to 15.77% ± 0.97% and in men to 22.6% ± 0.65%.The increases in CcOI-DC from ages 40-44 years compared to 80-84 years in women and men are significantly different with P < 0.01.For women over age 60 years,deficiency of CcOI expression is greater in those women who have had a cancer in their colon.The frequency of CcOI-DC,measured in men,increased in tissues adjacent to colon cancer,being 4.03% ± 0.27% in individuals free of neoplasia in the age range 55-64 yearsand 14.13% ± 0.35% in resected histologically normal tissue of men with cancer in the same age range,P < 0.001.Similar signifi cant differences were noted in older age ranges.The frequency of CcOI-DC crypts in the cecum and sigmoid colon of an individual are signifi cantly correlated,with an R2 = 0.414 for women and R2 = 0.528 for men,P < 0.001.This suggests that the factors determining the level of CcOI deficiency act throughout the colon.Most defective crypts are in clusters of two or more,a likely consequence of crypt fission.In the non-neoplastic margins of cancers,crypts are frequently defi cient for CcOI,and such crypts may appear in large clusters,some containing more than 100 defi cient crypts.CcOI defi ciency is also apparent in colon cancers and sometimes involves a large section of the tumor.Overall,CcOI deficient cells can be visualized in segments of crypts,in whole crypts that increase in frequency with age,in crypts undergoing f ission,in clusters of crypts where the clusters increase in size with age,in increased frequency near tumors,in large clusters in the intimate margins of tumors,and in the tumors themselves.There is no clear dividing line between early stages that can be considered aspects of aging and later stages that can be considered aspects of the progression to cancer.This ambiguity may re ect a rather general situation leading to adult cancer where the early stages of cellular change appear to be relatively innocuous features of the aging process but over decades may evolve into malignancy.CONCLUSION: CcOI defi cient crypts increase in frequency with age,and clusters of defi cient crypts are associated with,and may give rise to,colon cancer.Carol Bernstein Alexander Facista Huy Nguyen Beryl Zaitlin Nadia Hassounah Cristy Loustaunau Claire Margaret Payne Bhaskar Banerjee Steve Goldschmid V Liana Tsikitis Robert Krouse Harris Bernstein 2010World Journal of Gastrointestinal Oncology2010,2,12:5
9Development of the Documentation and Appraisal Review Tool for systematic reviews显示文摘AIM:To develop a tool to more explicitly assess and document the quality of systematic reviews.METHODS:We developed the Documentation and Appraisal Review Tool(DART)using epidemiologic principles of study design and the following resources:the modified Overview Quality Assessment Questionnaire(modified OQAQ),Assessment of Multiple Systematic Reviews(AMSTAR),the Cochrane Handbook,and the standards promoted by the Agency for Healthcare Research and Quality,and the Institutes of Medicine(IOM).We designed the DART tool to include the following:more detail to provide guidance and improve standardization of use,an approach to assess quality of systematic reviews addressing a variety of research designs,and additional space for recording notes to facilitate recall.DART underwent multiple rounds of testing with methodologists of varying levels of training and experience.Based on the results of six phases of pilot testing,we revised DART to improve performance,clarity and consistency.Pilot testing also included comparisons between DART,and the two most commonly used tools to evaluate the quality of systematic reviews,the modified OQAQ and AMSTAR.RESULTS:Compared to AMSTAR and modified OQAQ,DART includes two unique questions and several questions covered by modified OQAQ or AMSTAR but not both.Modified OQAQ and DART had the highest reporting consistency.Four AMSTAR questions were unclear and elicited inconsistent responses.Identifying reviewer rationale was most difficult using the modified OQAQ tool,and easiest using DART.DART allowsfor documentation of reviewer rationale,facilitating reconciliation between reviewers and documentation for future updates.DART also provides a comprehensive,systematic approach for reviewers with limited experience with systematic review methodology,to critically analyze systematic reviews.In addition,DART is the only one of the three tools to explicitly include quality review for biases specific to observational studies.This is now more widely recognized as important for assessing risk in order to generate recommendations that balance benefit to harm.The tool also includes the assessment of standards recommended by the March 2011 IOM Standards for Systematic Review.CONCLUSION:This comprehensive tool improves upon existing tools for assessing the quality of systematic reviews and guides reviewers through critically analyzing a systematic review.Rebecca L Diekemper Belinda K Ireland Liana R Merz 2015World Journal of Meta-Analysis2015,3,3:5
10Cumulative positive fluid balance is a risk factor for acute kidney injury and requirement for renal replacement therapy after liver transplantation显示文摘AIM To analyze whether fluid overload is an independent risk factor of adverse outcomes after liver transplantation(LT).METHODS One hundred and twenty-one patients submitted to LT were retrospectively evaluated.Data regarding perioperative and postoperative variables previously associated with adverse outcomes after LT were reviewed.Cumulative fluid balance(FB) in the first 12 h and 4 d after surgery were compared with major adverse outcomes after LT.RESULTS Most of the patients were submitted to a liberal approach of fluid administration with a mean cumulative FBover 5 L and 10 L,respectively,in the first 12 h and 4 d after LT.Cumulative FB in 4 d was independently associated with occurrence of both AKI and requirement for renal replacement therapy(RRT)(OR = 2.3;95%CI:1.37-3.86,P = 0.02 and OR = 2.89;95%CI:1.52-5.49,P = 0.001 respectively).Other variables on multivariate analysis associated with AKI and RRT were,respectively,male sex and Acute Physiology and Chronic Health Disease Classification System(APACHE II) levels and sepsis or septic shock.Mortality was shown to be independently related to AST and APACHE II levels(OR = 2.35;95%CI:1.1-5.05,P = 0.02 and 2.63;95%CI:1.0-6.87,P = 0.04 respectively),probably reflecting the degree of graft dysfunction and severity of early postoperative course of LT.No effect of FB on mortality after LT was disclosed.CONCLUSION Cumulative positive FB over 4 d after LT is independently associated with the development of AKI and the requirement of RRT.Survival was not independently related to FB,but to surrogate markers of graft dysfunction and severity of postoperative course of LT.Liana Codes Ygor Gomes de Souza Ricardo Azevedo Cruz D'Oliveira Jorge Luiz Andrade Bastos Paulo Lisboa Bittencourt 2018World Journal of Transplantation2018,8,2:4
11Giorgio Vasari’s Fine Arts From the Vite of 1550:The Splendor of Creativity and Design显示文摘Giorgio Vasari’s conception of artistic creativity is related to his theory of painting. He proposes two alternatives in a painter’s development or achievement of artistic creativity: imitation (imitazione) and invention (invenzione).Imitation is the copying of art as a method of learning, whereas invention is independent of imitation and constitutes the means for conceiving artistic ideas. Imitation serves to guide and teach the artist in composing and creating perfection. Vasari maintains that artists must study antiquity and the masters, so that they may learn how others acquired the experience of imitating nature. For Vasari, imitation draws upon three different sources: the first two are copying from nature (copia dal vero) and the third one is selecting from one’s work (imitare se stessi). He emphasizes that copying from nature is important for the artist so that he may learn to create forms that are alive as visualized in the Fine Arts.Liana De Girolami Cheney 2017Journal of Literature and Art Studies2017,7,2:3
12TWO NEW LIGNANS FROM MAGNOLIA BIONDII PAMP显示文摘TWONEWLIGNANSFROMMAGNOLIABIONDIIPAMP¥YuLianaMA;CuiQiuHAN(NationalLaboratoryofNaturalandBiomimeticDrugs,BeijingMedicalUniversi...Yu Liana MA Cui Qiu HAN (National Laboratory of Natural and Biomimetic Drugs,Beijing Medical University, Beijing 100083) 1994Chinese Chemical Letters1994,5,10:3
13Clinical epidemiology of chronic viral hepatitis B:A Tuscany real-world large-scale cohort study显示文摘AIM To build a regional database of chronic patients to define the clinical epidemiology of hepatitis B virus(HBV)-infected patients in the Tuscan public health care system.METHODS This study used a cross-sectional cohort design. We evaluated chronic viral hepatitis patients with HBV referred to the outpatient services of 16 hospital units. Information in the case report forms included main demographic data, blood chemistry data, viral hepatitis markers, instrumental evaluations, and eligibility for treatment or ongoing therapy and liver transplantation. RESULTS Of 4015 chronic viral hepatitis patients, 1096(27.3%) were HBV infected. The case report form was correctly completed for only 833 patients(64% males, 36% females; mean age 50.1 ± 15.4). Of these HBV-infected patients, 73% were Caucasian, 21% Asian, 4% Central African, 1% North African and 1% American. Stratifying patients by age and nationality, we found that 21.7% of HBV-infected patients were aged < 34 years(only 2.8% were Italian). The most represented routes of transmission were nosocomial/dental procedures(23%), mother-to-child(17%) and sexual transmission(12%). The most represented HBV genotypes were D(72%) and A(14%). Of the patients, 24.7% of patients were HBe Ag positive, and 75.3% were HBe Ag negative. Of the HBV patients 7% were anti-HDV positive. In the whole cohort, 26.9% were cirrhotic(35.8% aged < 45 years), and 47% were eligible for or currently undergoing treatment, of whom 41.9 % were cirrhotic. CONCLUSION Only 27.3% of chronic viral hepatitis patients were HBV infected. Our results provide evidence of HBV infection in people aged < 34 years, especially in the foreign population not protected by vaccination. In our cohort of patients, liver cirrhosis was also found in young adults.Cristina Stasi Caterina Silvestri Roberto Berni Maurizia Rossana Brunetto Anna Linda Zignego Cristina Orsini Stefano Milani Liana Ricciardi Andrea De Luca Pierluigi Blanc Cesira Nencioni Donatella Aquilini Alessandro Bartoloni Giampaolo Bresci Santino Marchi Franco Filipponi Piero Colombatto Paolo Forte Andrea Galli Sauro Luchi Silvia Chigiotti Alessandro Nerli Giampaolo Corti Rodolfo Sacco Paola Carrai Angelo Ricchiuti Massimo Giusti Paolo Almi Andrea Cozzi Silvia Carloppi Giacomo Laffi Fabio Voller Francesco Cipriani 2018World Journal of Hepatology2018,10,5:3
14Prognostic relevance of normocytic anemia in elderly patients affected by cardiovascular disease显示文摘BACKGROUND Anemia associated with cardiovascular diseases(CVD) is a common condition in older persons. Prevalence and prognostic role of anemia were extensively studied in patients with myocardial infarction(MI) or congestive heart failure(CHF) whereas limited data were available on patients with atrial fibrillation(AF). This study was conducted to assess the clinical prevalence and prognostic relevance of anemia in elderly patients affected by AF and other CVDs.METHODS A total of 866 elderly patients(430 men and 436 women, age: 65-98 years, mean age: 85 ± 10 years) were enrolled.Among these patients, 267 patients had acute non-ST-segment elevation MI(NSTEMI), 176 patients had acute CHF, 194 patients had acute AF and 229 patients were aged-matched healthy persons(CTR). All parameters were measured at the hospital admission and cardiovascular mortality was assessed during twenty-four months of follow-up.RESULTS The prevalence of anemia was higher in NSTEMI, CHF and AF patients compared to CTR subjects(50% vs. 15%, P <0.05), with normocytic anemia being the most prevalent type(90%). Adjusted mortality risk was higher in anemic patient versus non-anemic patient in all the groups of patients [NSTEMI: hazard ratio(HR) = 1.81, 95% CI: 1.06-2.13;CHF: HR = 2.49, 95% CI:1.31-4.75;AF: HR = 1.98, 95% CI: 1.01-3.88]. Decreased hemoglobin levels(P = 0.001) and high reticulocyte index(P = 0.023) were associated with higher mortality in CVD patients.CONCLUSIONS The significant associations between CVD and anemia and the prognostic relevance of anemia for elderly patients with CVD were confirmed in this study. The presence of anemia in AF patients is associated with a two-fold increased mortality risk compared with non-anemic AF patients. Low hemoglobin and high reticulocyte count independently predict mortality in elderly patients with CVD.Liana Spazzafumo Fabiola Olivieri Jacopo Sabbatinelli Roberta Galeazzi Rina Recchioni Fiorella Marcheselli Paola Tamburrini Roberto Antonicelli 2021Journal of Geriatric Cardiology2021,18,8:3
15After Administration of Intravenous Epinephrine for bee Sting-induced Anaphylaxis: Kounis Syndrome or Epinephrine Effect?显示文摘To the Editor: In the very important report published in Chinese Medical Journal,[1] a 50-year-old male patient, stented with a bare metal stent followed by 3 overlapping drug-eluting stents, developed anaphylactic reaction following a bee sting that was treated with intravenous 0.1 mg epinephrine at a 1:100,000 together with intravenous methylprednisolone, chlorpheniramine maleate, and ranitidine.He developed, immediately after, an anterior wall myocardial infarction, and subsequent coronary arteriography revealed total occlusion in the proximal left anterior descending stent and 90% stenosis with tissue growth in the mid-stent.The authors concluded that the acute myocardial infarction occurred due to acute stent thrombosis caused by exogenous epinephrine administration.This report, however, raises important questions related to the cause and pathophysiology of these events.Nicholas G Kounis George D Soufras Dimitrios Lianas Nicholas Patsouras 2016Chinese Medical Journal2016,,4:2
16Cloud federation in a layered service model显示文摘David Villegas Norman Bobroff Ivan Rodero Javier Delgado Yanbin Liu Aditya Devarakonda Liana Fong S. Masoud Sadjadi Manish Parashar 2012Journal of Computer and System Sciences2012,,5:2
17Nitrogen and Carbon Isotope Data of Olenekian to Anisian Deposits from Kamenushka/South Primorye, Far-Eastern Russia and Their Palaeoenvironmental Significance显示文摘The Kamenushka Formation, exposed in the northern part of South Primorye(Kamenushka-1 and Kamenushka-2 sections), is one of the few localities in the world with richly fossiliferous Lower–Upper Olenekian sedimentary successions. Lower to Middle Triassic ammonoid-, brachiopod-and conodont-bearing silty-clayey deposits of the Kamenushka-1 and Kamenushka-2 sections have been isotope-geochemically investigated in detail. As a result, these sections, together with the previously investigated Abrek Section, exposed in the southern part of South Primorye, provide almost complete 15 Norg-and 13 Corg-records for the Lower Triassic of this region. Nine Nisotope intervals and the five negative C-isotope excursions, reflecting, apparently, unstable climatic and hydrological conditions, have been distinguished in the Lower Triassic of South Primorye. On the basis of the new C-isotope data the Mesohedenstroemia bosphorensis Zone(upper part), Shimanskyites shimanskyi and Neocolumbites insignis zones of South Primorye are correlated now with the Lower Smithian part of the Yinkeng Formation, the Upper Smithian part of the Helongshan Formation and the Middle Spathian part of the Nanlinghu Formation in South China, respectively, as has been observed in the Abrek, Kamenushka-2, West Pingdingshan and Majiashan sections.Yuri D Zakharov Micha Horacek Alexander M Popov Liana G Bondarenko 2018Journal of Earth Science2018,29,4:2
18Results, Outcome Predictors, and Complications after Stapled Transanal Rectal Resection for Obstructed Defecation显示文摘Giuseppe Gagliardi M.D. Mario Pescatori M.D. F.R.C.S. E.B.S.Q. Donato F. Altomare M.D. Gian Andrea Binda M.D. Corrado Bottini M.D. Giuseppe Dodi M.D. Vincenzino Filingeri M.D. Giovanni Milito M.D. Marcella Rinaldi M.D. Giovanni Romano M.D. Liana Spazzaf 2008Diseases of the Colon & Rectum2008,,2:2
19Chemical and pharmacological evaluation of Hypericum perforation extracts显示文摘KEY WORDS Hypericum perforation; High pressure liquid chromatography; serotonin uptake inhibitors; tree radicals; antioxidants; hyperforin; hypericin; quercetin; rutinABSTRACTAIM: To determine the concentrations of chemical characteristic to extracts of leaves and flowers of Hypericum perforatnm (St John’s wort) in a number of selected samples and, following chemical characterization, to investigate the effects of these extracts on several pharmacological properties including effects of the extracts on inhibition of 5-hydroxytryptamine (5-HT) uptake and on an-tioxidant properties. METHODS: The samples were analyzed for the presence of characteristic chemicals by high performance liquid chromatography (HPLC) directly coupled to ultraviolet wavelength absorbance and positive or negative mode electrospray mass spectrometric detection. The effects of extracts on 5-HT uptake were determined by quantifying 3H-5-HT incorporation into rat hip-pocampal prisms. Estimates of effects of extracts on free radicalB Duff SLOLEY Liana J URICHUK LING Lei GU Lie-Dong Ronald T COUTTS Peter K T PANG Jacqueline J SHAN 2000Acta Pharmacologica Sinica2000,21,12:2
20Neuronal and peripheral damages induced by synthetic psychoactive substances: an update of recent findings from human and animal studies显示文摘Preclinical and clinical studies indicate that synthetic psychoactive substances,in addition to having abuse potential,may elicit toxic effects of varying severity at the peripheral and central levels.Nowadays,toxicity induced by synthetic psychoactive substances poses a serious harm for health,since recreational use of these substances is on the rise among young and adult people.The present review summarizes recent findings on the peripheral and central toxicity elicited by “old” and “new” synthetic psychoactive substances in humans and experimental animals,focusing on amphetamine derivatives,hallucinogen and dissociative drugs and synthetic cannabinoids.Giulia Costa Maria Antonietta De Luca Gessica Piras Jacopo Marongiu Liana Fattore Nicola Simola 2020Neural Regeneration Research2020,15,5:2
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