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| 1 | Strong ozone production at a rural site in the North China Plain: Mixed effects of urban plumes and biogenic emissions显示文摘Regional ozone(O_3) pollution has drawn increasing attention in China over the recent decade, but the contributions from urban pollution and biogenic emissions have not been clearly elucidated. To better understand the formation of the regional O_3 problem in the North China Plain(NCP), intensive field measurements of O_3 and related parameters were conducted at a rural site downwind of Ji'nan, the capital city of Shandong province, in the summer of 2013. Markedly severe O_3 pollution was recorded, with the O_3 mixing ratios exceeding the Chinese national ambient air quality standard on 28 days(a frequency of 78%) and with a maximum hourly value of 198 ppbv. Extensive regional transport of wellprocessed urban plumes to the site was identified. An observation-constrained chemical box model was deployed to evaluate in situ photochemical O_3 production on two episodes.The results show that the in situ formation accounted for approximately 46% of the observed O_3 accumulation, while the remainder(~54%) was contributed by regional transport of the O_3-laden urban plumes. The in situ ozone production was in a mixed controlled regime that reducing either NOx or VOCs would lead to a reduction of ozone formation. Biogenic VOCs played an important role in the local ozone formation. This study demonstrates the significant mixed effects of both anthropogenic pollution from urban zones and biogenic emission in rural areas on the regional O_3 pollution in the NCP region,and may have general applicability in facilitating the understanding of the formation of secondary pollution over China. | Ruihan Zong Xue Yang Liang Wen Caihong Xu Yanhong Zhu Tianshu Chen Lan Yao Liwei Wang Junmei Zhang Lingxiao Yang Xinfeng Wang Min Shao Tong Zhu Likun Xue Wenxing Wang | 2018 | Journal of Environmental Sciences2018，30，9： | 8 |
| 2 | Pitting corrosion of 2Cr13 stainless steel in deep-sea environment显示文摘Pitting corrosion of 2Cr13 stainless steel was investigated by deep-sea exposure test at various depths of 500 m,800 m and 1200 m in the South China Sea for 4 months.With the aid of electrochemical measurements in simulated deep-sea environments and grey relational analysis,the influence of deepsea environments on passive film and the mechanism of pitting corrosion were discussed.The results indicated that with the increase of sea depth,pitting depth of 2Cr13 stainless steel increased,which can be attributed to the change of chemical composition and the degradation of pitting resistance of passive film.Film growth was greatly retarded in the condition of low seawater temperature and low dissolved oxygen content of deep sea,resulting in an unstable and vulnerable film.Pitting depth was most influenced by hydrostatic pressure,which can increase the adsorption and penetration of Cl-ion,and promote the proliferation of point defects in passive film,leading to rapid deconstruction of protective oxides of the film.Pitting sensitivity of 2Cr13 stainless steel increased eventually with the combination of accelerated dissolution and suppressed self-healing of passive film in deep sea. | Xinhua Wang Lin Fan Kangkang Ding Likun Xu Weimin Guo Jian Hou Tigang Duan | 2021 | Journal of Materials Science & Technology2021，，5： | 6 |
| 3 | Design and Optimization of a Full-Generation System for Marine LNG Cold Energy Cascade Utilization显示文摘This paper took a 100,000 DWT LNG fuel powered ship as the research object.Based on the idea of'temperature matching,cascade utilization'and combined with the application conditions of the ship,a horizontal three-level nested Rankine cycle full-generation system which combined the high-temperature waste heat of the main engine flue gas with the low-temperature cold energy of LNG was proposed in this paper.Furthermore,based on the analysis and selection of the parameters which had high sensitivity to the system performance,the parameters of the proposed system were optimized by using the genetic algorithm.After optimization,the exergy efficiency of the marine LNG gasification cold energy cascade utilization power generation system can reach 48.06%,and the thermal efficiency can reach 35.56%.In addition,this paper took LNG net power generation as the performance index,and compared it with the typical LNG cold energy utilization power generation system in this field.The results showed that the unit mass flow LNG power generation of the system proposed in this paper was the largest,reaching 457.41 k W. | SUN Xiaofei YAO Shouguang XU Jinjin FENG Guozeng YAN Likun | 2020 | Journal of Thermal Science2020，29，3： | 3 |
| 4 | InGaP/InGaAs/GaAs DHBT structural materials grown by GSMBE显示文摘Heterojunction bipolar transistor (HBT) is of great interest for the application to microwave power and analog circuits. As known, decreasing bandgap energy of the base layer in HBT can result in a smaller turn-on voltage. Using InGaAs as a base material in GaAs HBT is a possible approach to achieve the aim. In this work, a novel InGaP/InGaAs/GaAs double heterojunction bipolar transistor (DHBT) structure with an InGaAs base was designed and grown by gas source molecular beam epitaxy (GSMBE). High-quality InGaAs/GaAs hetero epi-layers and a good doping figure were obtained through optimizing the layer structure and the growth condition. The DHBT devices of a 120 μm×120 μm emitter area were fabricated by normal process and the good DC performance was obtained. A breakdown voltage of 10 V and an offset voltage of just 0.4 V were achieved. These results indicate that the InGaP/InGaAs/GaAs DHBT is suitable for low power-dissipation and high power applications. | AI Likun XU Anhuai SUN Hao ZHU Fuying QI Ming | 2006 | Rare Metals2006，25，z2： | 2 |
| 5 | Peroxyacetyl nitrate measurements by thermal dissociation-chemical ionization mass spectrometry in an urban environment: performance and characterizations显示文摘Peroxyacetyl 硝酸盐(平底锅) 是光化学的烟雾的重要指示物并且在人的健康和植被生长上有不利效果。热分离化学药品电离团 spectrometry (TD 计算机集成制造系统) 的一种快速、高度选择的技术最近被开发在实时测量许多平底锅;然而,它可以面对氮的氧化物服从于人工制品(没有) 。在这研究,我们测试了导致由的 PAN 信号的干扰没有,在城市的环境评估了 TD 计算机集成制造系统的性能,并且在城市的香港调查了平底锅的集中和形成。不在 TD 计算机集成制造系统引起了 PAN 信号的重要低估,与没有集中严厉地增加并且与平底锅丰富稍微减少的低估。一个公式被导出与集中连接平底锅信号的损失没有并且平底锅,它能在平底锅大小被用于数据修正。从 TDCIMS 的改正的平底锅数据与从有电子俘获察觉的通常使用的煤气的层析的那些一致,它在在哪个不是丰富的城市的环境证实 TD 计算机集成制造系统的实用程序。在 2010 的秋天,混合比率的时时平均的平底锅从 0.06 ppbv 变化了到 5.17 ppbv,显示在城市的香港的光化学的污染的出现。平底锅的形成效率每 100 ppbv 臭氧象 3.9 ~ 5.9 ppbv 一样在污染事件期间高。效率没有 x 集中显示出在线性附近的增加,建议为平底锅污染的 NOx 减小的一条控制政策。 | Xinfeng Wang Tao Wang Likun Xue Wei Nie Zheng Xu Steven C. N. Poon Wenxing Wang | 2017 | Frontiers of Environmental Science & Engineering2017，11，4： | 2 |
| 6 | Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial显示文摘Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection.Blocking CD147 via anti-CD147 antibody could suppress the in vitro SARS-CoV-2 replication.Meplazumab is a humanized anti-CD147 IgG_(2) monoclonal antibody,which may effectively prevent SARS-CoV-2 infection in coronavirus disease 2019(COVID-19)patients.Here,we conducted a randomized,double-blinded,placebo-controlled phase 1 trial to evaluate the safety,tolerability,and pharmacokinetics of meplazumab in healthy subjects,and an open-labeled,concurrent controlled add-on exploratory phase 2 study to determine the efficacy in COVID-19 patients.In phase 1 study,59 subjects were enrolled and assigned to eight cohorts,and no serious treatment-emergent adverse event(TEAE)or TEAE grade≥3 was observed.The serum and peripheral blood Cmax and area under the curve showed non-linear pharmacokinetic characteristics.No obvious relation between the incidence or titer of positive anti-drug antibody and dosage was observed in each cohort.The biodistribution study indicated that meplazumab reached lung tissue and maintained>14 days stable with the lung tissue/cardiac blood-pool ratio ranging from 0.41 to 0.32.In the exploratory phase 2 study,17 COVID-19 patients were enrolled,and 11 hospitalized patients were involved as concurrent control.The meplazumab treatment significantly improved the discharged(P=0.005)and case severity(P=0.021),and reduced the time to virus negative(P=0.045)in comparison to the control group.These results show a sound safety and tolerance of meplazumab in healthy volunteers and suggest that meplazumab could accelerate the recovery of patients from COVID-19 pneumonia with a favorable safety profile. | Huijie Bian Zhao-Hui Zheng Ding Wei Aidong Wen Zheng Zhang Jian-Qi Lian Wen-Zhen Kang Chun-Qiu Hao Jing Wang Rong-Hua Xie Ke Dong Jie-Lai Xia Jin-Lin Miao Wen Kang Guoquan Li Di Zhang Mingru Zhang Xiu-Xuan Sun Likun Ding Kui Zhang Junfeng Jia Jin Ding Zhiqin Li Yanyan Jia Lin-Na Liu Zhe Zhang Zhao-Wei Gao Hong Du Na Yao Qing Wang Ke Wang Jie-Jie Geng Bin Wang Ting Guo Ruo Chen Yu-Meng Zhu Li-Juan Wang Qian He Rui-Rui Yao Ying Shi Xiang-Min Yang Jian-Sheng Zhou Yi-Nan Ma Ya-Tao Wang Xue Liang Fei Huo Zhe Wang Yang Zhang Xu Yang Ye Zhang Lu-Hua Gao Ling Wang Xiao-Chun Chen Hao Tang Shuang-Shuang Liu Qing-Yi Wang Zhi-Nan Chen Ping Zhu | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 2 |
| 7 | Porous carbon spheres via microwave-assisted synthesis for capacitive deionization显示文摘 | Yong Liu Likun Pan Taiqiang Chen Xingtao Xu Ting Lu Zhuo Sun Daniel H.C. Chua | 2015 | Electrochimica Acta2015，，： | 2 |
| 8 | Quantifi cation of the Atmospheric Corrosion of 304 and 2205 Stainless Steels Using Electrochemical Probes Based on Thevenin Electrochemical Equivalent Circuit Model显示文摘Stainless steel(SS)is one of the most widely used engineering materials in marine engineering.However,its corrosion in the marine atmospheric environment due to the high concentration of Cl-is a problem.The SS corrosion is a threat to the development and security of marine industry;therefore,evaluating the corrosion resistance of SSs is necessary.In this work,atmospheric corrosion detection probes based on a symmetrical electrode system were used to study the corrosion behaviors of 304 SS and 2205 duplex stainless steel(DSS)in a simulated marine atmosphere.A theoretical model for electrochemical noise(EN)data analysis based on the Thevenin electrochemical equivalent circuit(EEC)model was established.The relationship between the EN characteristic parameters and the corrosion rate was obtained.The Thevenin EEC model analysis showed that the relationship between the noise resistance(Rn),the noise impedance[Rsn(f)],and the impedance modulus(|Z(f)|)was Rn≈Rsn=■.Thus,Rn and Rsn can be used as indicators for quantitative corrosion evaluation.The results of EN detection for the 304 SS and 2205 DSS showed that in a simulated marine atmospheric environment,the passive fi lms on the two SSs were relatively intact at the initial exposure stage,and their dissolution rates were slow.The corrosion resistance of the 2205 DSS was higher than that of the 304 SS.With the deposition of Cl-on the SS surface,pitting was initiated and the dissolution rate increased.The pitting initiation process on the SS surface was random,and part of the active pores could be repassivated. | Yu Zhu Yang Song Likun Xu Zhenbo Qin Shizhe Song Wenbin Hu Da-Hai Xia | 2020 | Transactions of Tianjin University2020，26，3： | 2 |
| 9 | SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2显示文摘Dear Editor,SARS-coronavirus-2(SARS-CoV-2)Omicron variant(B.1.1.529)is of great concern to the world due to its multiple mutations that may have an impact on transmissibility and immune evasion.1 Compared to the wild type(WT),Omicron carries as many as 30 single point mutations,3 deletion mutation and one insertion mutation on its spike protein.Strikingly,there are 15 mutations observed in the Omicron receptor-binding domain(RBD),10 of which are in the receptor-binding motif(RBM)that human angiotensin-converting enzyme 2(ACE2)and most monoclonal antibodies(mAbs)interact directly with.As a comparison,the currently dominant variant Delta(B.1.617.2)has only 2 mutations(L452R and T478K)in its RBM and additional K417N and E484K mutations sometimes.Therefore,Omicron variant may significantly impact the binding affinity to ACE2 and effectiveness of currently available mAbs.Consequently,Omicron mutant has aroused wide concern,many countries have taken measures on entry restrictions to prevent its rapid spread.However,the transmissibility and immune evasion risk of Omicron have not been properly evaluated. | Leyun Wu Liping Zhou Mengxia Mo Tingting Liu Chengkun Wu Chunye Gong Kai Lu Likun Gong Weiliang Zhu Zhijian Xu | 2022 | Signal Transduction and Targeted Therapy2022，7，2： | 2 |
| 10 | Spreading kinetics of a Sn-30Bi-0.5Cu alloy on a Cu substrate显示文摘The reactive wetting kinetics of a Sn-30Bi-0.5Cu Pb-free solder alloy on a Cu substrate was investigated by the sessile drop method from 493 to 623 K.The triple line frontier,characterized by the drop base radius R was recorded dynamically with a high resolution CCD using different spreading processes in an Ar-H 2 flow.We found a good agreement with the De Gennes model for the relationship between ln(dR/dt) and lnR for the spreading processes at 493 and 523 K.However,a significant deviation from the De Gennes model was found for the spreading processes at 548 and 623 K.Our experimental results show a complicated temperature effect on the spreading kinetics.Intermetallics at the Sn-30Bi-0.5Cu/Cu interface were identified as Cu 6 Sn 5 adjacent to the solder and Cu 3 Sn adjacent to the Cu substrate.The intermetallic compounds effectively enhanced the triple line mobility because of reaction product formation at the diffusion frontier. | ZANG LiKun YUAN ZhangFu ZHAN YaPeng WANG ChenYu XU BingSheng | 2012 | Chinese Science Bulletin2012，57，6： | 1 |
| 11 | Effect of Nano Al Pigment on the Anticorrosive Performance of Waterborne Epoxy Coatings显示文摘This paper presents the results regarding the effect of nano aluminum powder pigment concentration on the protective properties of waterborne epoxy films in 3.5 wt pct NaCl solution.The anticorrosive performance of the coatings with 0.5,1,and 3 wt pct pigments and none pigment were investigated using electrochemical impedance spectroscopy (EIS),scanning electron microscopy (SEM) and Raman spectroscopy techniques. The results show that adding appropriate amount of nano-aluminium powder pigment can enhance the barrier properties of the epoxy coating,which is attributed to the surface effect of nanoparticles and the compatibility of the pigment with the waterborne epoxy coatings. | Lili XUE Likun XU Qingfen LI | 2007 | Journal of Materials Science & Technology2007，23，4： | 1 |
| 12 | Influences of configuration and molecular weight of hemicelluloses on their paper-strengthening ef- fects显示文摘 | Likun Bai Huiren Hu Jianfeng Xu | 2012 | Carbohydrate Polymers2012，88，4： | 1 |
| 13 | A comparative study on IrO 2 –Ta 2 O 5 coated titanium electrodes prepared with different methods显示文摘 | Likun Xu Yonglei Xin Juntao Wang | 2008 | Electrochimica Acta2008，，6： | 1 |
| 14 | PMD:A resource for archiving and analyzing protein microarray data显示文摘 | Xu Zhaowei Huang Likun Zhang Hainan | 2016 | Scientific Reports2016，，19： | 1 |
| 15 | Oil pipeline leak detection system based on acoustic wave technology 显示文摘 | Wang Likun Xu Bin Wang Hongchao | 2012 | Applied Mechanics and Materi- als2012，，： | 1 |
| 16 | Synthesis of IsocyanateMicrocapsules and Micromechanical Behavior Improvement ofMicrocapsule Shells by Oxygen Plasma Treated Carbon Nanotubes显示文摘 | Wei Wang Likun Xu Feng Liu et ai | 2013 | Journal of Materials Chemistry A2013，1，3： | 1 |
| 17 | National survey of the medical treatment status for non-small cell lung cancer (NSCLC) in China显示文摘 | Cong Xue Zhihuang Hu Wei Jiang Yuanyuan Zhao Fei Xu Yan Huang Hongyun Zhao Jingxun Wu Yang Zhang Liping Zhao Jing Zhang Likun Chen Li Zhang | 2012 | Lung Cancer2012，，2： | 1 |
| 18 | Pedestrian trajectory prediction in crossing scenario using fuzzy logic and switching Kalman filter显示文摘Pedestrian trajectory prediction plays an important role in bothadvanced driving assistance system(ADAS) and autonomous vehicles. An algorithm for pedestrian trajectory prediction in crossing scenario is proposed. To obtain features of pedestrian motion, we develop a method for data labelling and pedestrian body orientation regression. Using the hierarchical features as domain of discourse, fuzzy logic rules are built to describe the transition between different pedestrian states and motion models. With derived probability of each type of motion model we further predict the pedestrian trajectory in the next 1.5 s using switching Kalman filter(KF). The proposed algorithm is further verified in our dataset, and the result indicates that the proposed algorithm successfully predicts pedestrian's crossing behavior 0.4 s earlier before pedestrian moves. Meanwhile, the precision of predicted trajectory surpasses other methods including interacting multi-model KF and dynamic Bayesian network(DBN). | Wang Likun Liu Lu Yu Dameng Xu Qing Wang Jianqiang | 2018 | The Journal of China Universities of Posts and Telecommunications2018，25，6： | 1 |
| 19 | Saponins from Platycodi Radix ameliorate high fat diet-induced obesity in Mice 显示文摘 | Han Likun Zheng Yinan Xu Baojun | 2002 | J Nutr2002，132，： | 1 |
| 20 | Platycodi Radix affects lipid metabolism in mice with high fat diet-induced Obesity显示文摘 | Han Likun Xu Baojun Yoshiyuki Kimura | 2000 | J Nutr2000，130，11： | 1 |
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