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| 1 | Food contamination as a pathway for lead exposure in children during the 2010–2013 lead poisoning epidemic in Zamfara,Nigeria显示文摘In 2010, an estimated 400 to 500 children died of acute lead poisoning associated with artisanal gold mining in Zamfara, Nigeria. Processing of gold ores containing up to 10% lead within residential compounds put residents, especially children, at the highest risk. Principal routes of exposure were incidental ingestion and inhalation of contaminated soil and dusts. Several Nigerian and international health organizations collaborated to reduce lead exposures through environmental remediation and medical treatment. The contribution of contaminated food to total lead exposure was assessed during the environmental health response. Objectives of this investigation were to assess the influence of cultural/dietary habits on lead exposure pathways and estimate the contribution of contaminated food to children's blood lead levels(BLLs). A survey of village dietary practices and staple food lead content was conducted to determine dietary composition, caloric intakes, and lead intake. Potential blood lead increments were estimated using bio-kinetic modeling techniques. Most dietary lead exposure was associated with contamination of staple cereal grains and legumes during post-harvest processing and preparation in contaminated homes. Average post-harvest and processed cereal grain lead levels were 0.32 mg/kg and 0.85 mg/kg dry weight, respectively. Age-specific food lead intake ranged from 7 to 78 μg/day. Lead ingestion and absorption were likely aggravated by the dusty environment, fasting between meals, and nutritional deficiencies. Contamination of staple cereal grains by highly bioavailable pulverized ores could account for as much as 11%–34% of children's BLLs during the epidemic, and were a continuing source after residential soil remediation until stored grain inventories were exhausted. | Simba Tirima Casey Bartrem Ian von Lindern Margrit von Braun Douglas Lind Shehu Mohamed Anka Aishat Abdullahi | 2018 | Journal of Environmental Sciences2018，30，5： | 2 |
| 2 | The transloca-tion(6;9),associated with a specific subtype of acute myeloid leukemia,results in the fusion of two genes,dek and can,and the expression of a chimeric,leukemia-specific dek-can mRNA显示文摘 | von Lindern M Fornerod M van Baal S | | 0，，04： | 1 |
| 3 | Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes : characterization of the set gene显示文摘 | von Lindern M van Baal S Wiegant J | 1992 | Mol Cell Biol1992，12，8： | 1 |
| 4 | Off-pump coronary artery bypass surgery: physiology and anaesthetic management显示文摘 | Chassot PG Vander Lindern P Zaugg M | 2004 | Br J Anaesth2004，92，： | 1 |
| 5 | Type A botulinum toxin in the treatment of chronic facial pain associated with masticatory hyperactivity显示文摘 | Niederhagen B Bergé S | 2003 | J Oral Maxillofac Surg2003，61，7： | 1 |
| 6 | Type A botulinum toxin for the treatment of hypertrophy of the masseter and temporal muscles:an alternative treatment显示文摘 | von Lindern JJ Niederhagen B Appel T Berge S Reich RH | 2001 | Plast Reconstr Surg2001，107，： | 1 |
| 7 | Possible complications in arthroscopic lavage of the temporomandibular joint显示文摘 | von Lindern JJ Niederhagen B | 2001 | Mund Kiefer Gesichtschir2001，5，4： | 1 |
| 8 | Type A botuli- num toxin for the treatment of hypertrophy of the masseter and tem- poral muscles: an alternative treatment 显示文摘 | yon Lindern JJ Niederhagen B Appel T | 2001 | Plast Reconstr Surg2001，107，2： | 1 |
| 9 | Assessing remedial effectiveness through the blood lead: soil/dust lead relationship at the Bunker Hill Superfund Site in the Silver Valley of Idaho 显示文摘 | Von Lindern I Spalinger S Petroysan V | 2003 | Sci Total Environ2003，303，： | 1 |
| 10 | Assessing remedial effectiveness through the blood lead: soil/dust lead relationship at the Bunker Hill Superfund Site in the Silver Valley of Idaho 显示文摘 | Von Lindern I Spalinger S Petroysan V | 2003 | Sci Total Environ2003，303，： | 1 |
| 11 | Translation initiation factor 4E inhibits differentiation of erythroid progenitors显示文摘 | MONTSERRAT P D GODFREY G LINDERN M | 2005 | Mol Cell Biol2005，25，19： | 1 |
| 12 | Diagnosis and management of cervical teratomas显示文摘 | Berge SJ von Lindern JJ Appel BB | 2004 | Br J Oral Maxillofac Surg2004，42，： | 1 |
| 13 | Molecular mechanisms of pathology and treatment in Diamond Blackfan Anaemia显示文摘 | Horos R von Lindern M | 2012 | Br J Haema- tol2012，159，5： | 1 |
| 14 | Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene显示文摘 | von Lindern M van Baal S Wiegant J | 1992 | Mol Cell Biol1992，12，8： | 1 |
| 15 | A putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene显示文摘 | van Lindern M van Baal S Wiegant J | 1992 | Mol Cell Biol1992，12，8： | 1 |
| 16 | M?gliche Komplikationen bei der arthroskopischen Lavage des Kiefergelenks显示文摘 | S. Bergé J.-J. von Lindern B. Niederhagen T. Appel R. H. Reich | 2001 | Mund - Kiefer - und Gesichtschirurgie2001，，4： | 1 |
| 17 | Chronic myeloid leukemia may be associated with several bcr-abl transcripts including the acute lymphoid leukemia-type 7 kb transcript 显示文摘 | Selleri L von Lindern M Hermans A | 1990 | Blood1990，75，5： | 1 |
| 18 | Environmental lead contamination in the Rudnaya Pristan-Dalnegorsk mining and smelter district, Rus- sian Far East显示文摘 | Braun MC Lindern IH Khristoforova NK | 2002 | Environ Res2002，88，3： | 1 |
| 19 | Treamaent of frey's syndrome with type A botulinum toxin: case report显示文摘 | Lindern JV Niederbagen B Berge S | 2000 | J Oral Maxillofac Surg2000，58，： | 1 |
| 20 | Seasonal variations of lead concentration and loading rates in residential house dust in northern Idaho显示文摘 | Varduhi Petrosyan Margrit C. von Braun Susan M. Spalinger Ian H. von Lindern | 2005 | Journal of Hazardous Materials2005，，1： | 1 |
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