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| 1 | Functional Cooperativity of Enzymes of Phosphoinositide Conversion According to Synergistic Effects on Pectin Secretion in Tobacco Pollen Tubes显示文摘Arabidopsis phosphoinositide kinases PI4K1 和 PIP5K5 在在花粉试管位于极的尖端生长下面的方向性的泡 trafficking 的控制被含有。PI4K1 和 PIP5K5 催化 phosphoinositide 的关键连续的步变换,和它显得明显 PI4K1 形成的那 phosphatidylinositol-4-phosphate 可能由 PIP5K5 为 phosphatidylinositol-4,5-bisphosphate 形成充当底层。然而,这个假设试验性地没被探讨并且 PI4K1 的不同本地化模式, PIP5K5,并且另外产生 phosphatidylinositol 的 PI-synthases (PIS ) 建议另外的复杂性。这里, phosphoinositide 变换的酶的 synergistic 功能被估计。在烟草和 Arabidopsis 花粉试管, phosphoinositides 影响果胶的顶端的分泌物,和增加的果胶免职导致典型词法改变。PI4K1 和 PIP5K5 的催化地活跃、主导的否定变体系统地在烟草花粉试管被共同表示,与提高的果胶分泌物有关的形态学的发生被评估。数据支持在 trans-Golgi 网络的 PI4K1 和 PIP5K5 的建议功能的相互影响,调停方向性的泡 trafficking。另外包括 PIS isoforms, PIS1 或 PIS2 的合作表示实验,显示那果胶分泌物被对 PIS2 而非 PIS1 形成的 PtdIns 起作用的 PI4K1 和 PIP5K5 synergistically 调停。为在 PI 小径酶的特别 isoforms 之间的 phosphoinositide 中介的优先的 channeling 的可能的分枝被讨论。 | Till Ischebeck Linh Hai Vu Xu Jin Irene Stenzel Christian Lofke Ingo Heilmann | 2010 | Molecular Plant2010，3，5： | 1 |
| 2 | Zoning of Sustainable Agricultural Development in China显示文摘 | XU X HOU L LINH | 2006 | Agricultural Systems2006，87，1： | 1 |
| 3 | Simple-structured hydrophilic sensors for sweat uric acid detection with laser-engraved polyimide electrodes and cellulose paper substrates显示文摘Accurate detection of uric acid(UA)is crucial for diagnosing gout,yet traditional sweat-based UA sensors continue to face challenges posed by complex and costly electrode fabrication methods,as well as weakly hydrophilic substrates.Here,we designed and developed simple,low-cost,and hydrophilic sweat UA detection sensors constructed by carbon electrodes and cellulose paper substrates.The carbon electrodes were made by carbonized polyimide films through a simple,one-step laser engraving method.Our electrodes are porous,possess a large specific surface area,and are flexible and conductive.The substrates were composed of highly hydrophilic cellulose paper that can effectively collect,store,and transport sweat.The constructed electrodes demonstrate high sensitivity of 0.4μA Lμmol^(-1)cm^(-2),wide linear range of 2–100μmol/L.In addition,our electrodes demonstrate high selectivity,excellent reproducibility,high flexibility,and outstanding stability against mechanical bending,temperature variations,and extended storage periods.Furthermore,our sensors have been proven to provide reliable results when detecting UA levels in real sweat and on real human skin.We envision that these sensors hold enormous potential for use in the prognosis,diagnosis,and treatment of gout. | Linhe Xu Xueshan Hu Shuang Zhou Ze Zhang Junxian Zhang Chao Li Daxian Zuo Hao Liu Gang Chen Jiayu Wan Jinsong Tao | 2024 | Chinese Chemical Letters2024，35，3： | 0 |
| 4 | Impacts from the implementation of a Novel Clinical Pharmacist Training Program in Changsha,Hunan Province,China显示文摘The Ministry of Health and Family Planning of the People’s Republic of China issued a mandate to all hospitals to implement clinical pharmacy services by 2020.Implementation of clinical pharmacy services to provide pharmaceutical care is a priority.The Second Xiangya Hospital of Central South University in collaboration with the University of Alberta implemented a structured train-the-trainer program to train pharmacists to provide direct patient care in collaboration with physicians,to teach/mentor other pharmacists and students from Hunan province,and to conduct clinical pharmacy research.Following implementation of the program,the pharmacy department increased the number of clinical pharmacists,expanded the clinical pharmacy services,made changes to hospital policies,and received a financial award of five million renminbi(one million Canadian dollars)to support the department. | Ping Xu Da Xiong Xiang Andrew J.Cave Hoan Linh Banh | 2018 | Family Medicine and Community Health2018，6，2： | 0 |
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