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| 1 | Immunomagnetic separation and MS/SPR end-detection combined procedure for rapid detection of Staphylococcus aureus and protein A显示文摘 | Chen Lingli Deng Le Liu Linlin | 2007 | Biosensors and Bioelectronics2007，22，7： | 1 |
| 2 | Immunomagnetie separation and MS/SPR end-detection combined procedure for rapid detection of Staphylococcus aureus and protein A 显示文摘 | CHEN Lingli DENG Le LIU Linlin | 2007 | Biosens Bioelectron2007，22，7： | 1 |
| 3 | Orofacial Clefts in High Prevalence Area of Birth Defects—Five Counties,Shanxi Province,China,2000–2020显示文摘Summary What is already known on this topic?The prevalence of structural birth defects,especially neural tube defects,decreased after national folic acid(FA)supplementation initiation.What is added by this report?The prevalence of orofacial clefts(OFCs)in five counties of Shanxi Province in northern China,including most subtypes except cleft palate,showed a downward trend in the past two decades.In this study,pre-perinatal prevalence increased due to earlier detection. | Jufen Liu Yali Zhang Le Zhang Linlin Wang Lei Jin Nicholas D E Greene Zhiwen Li Aiguo Ren | 2021 | China CDC weekly2021，3，37： | 0 |
| 4 | Selected Structural Birth Defects--Shanxi Province,China,2000−2019显示文摘What is already known about this topic?To reduce the high prevalence of neural tube defects(NTDs)in rural areas of the country,the Ministry of Health of China(currently known as the National Health Commission)initiated a nationwide folic acid supplementation program in 2009.The prevalence of NTDs have decreased from 118.9/10,000 births to 31.5/10,000 in northern China from 2000 to 2014.What is added by this report?Based on a population-based birth-defect surveillance system,the prevalence of selected structural birth defects in 5 counties in northern China decreased significantly from 182.8/10,000 births to 119.3/10,000 during the past two decades.Perinatal(28 gestational weeks or more)structural birth defects decreased from 83.9%of total birth defects in 2000 to 59.9%in 2019.What are the implications for public health practice?Improving the compliance of periconceptional folic acid supplementation,the fortification of staple foods with folic acid,and the health education surrounding early prenatal check-ups should be considered to further reduce the risk of birth defects in the population. | Jufen Liu Linlin Wang Yali Zhang Le Zhang Lei Jin Zhiwen Li Aiguo Ren | 2020 | China CDC weekly2020，2，37： | 0 |
| 5 | Comparative histology,transcriptome,and metabolite profi ling unravel the browning mechanisms of calli derived from ginkgo(Ginkgo biloba L.)显示文摘Gingko biloba accumulates high levels of secondary metabolites of pharmaceutical value.Ginkgo calli develop a typical browning that reduces its regenerative capacity and thus its usefulness.To elucidate the browning mechanism,histological,transcriptomic,and metabolic alterations were compared between green and browning calli derived from immature ginkgo embryos.Histological observations revealed that browning calli had a more loosely arranged cell structure and accumulated more tannins than in green calli.Integrated metabolic and transcriptomic analyses showed that phenylpropanoid metabolism was specifi-cally activated in the browning calli,and 428 diff erentially expressed genes and 63 diff erentially abundant metabolites,including 12 fl avonoid compounds,were identifi ed in the browning calli compared to the green calli.Moreover,the expression of fl avonol synthase(FLS)and UDP-glucuronosyl-transferase(UGT)genes involved in the fl avonoid pathway was more than tenfold higher in browning calli than in green calli,thus promoting biosynthesis of fl avonol,which serves as a substrate to form glycosylated fl avonoids.Flavonoid glycosides constituted the major coloring component of the browning calli and may act in response to multiple stress conditions to delay cell death caused by browning.Our results revealed the cellular and biochemical changes in browning callus cells that accompanied changes in expression of browning-related genes,providing a scientifi c basis for improving ginkgo tissue culturability. | Xiaoming Yang Qi Xu Linlin Le Tingting Zhou Wanwen Yu Guibin Wang Fang-Fang Fu Fuliang Cao | 2023 | Journal of Forestry Research2023，34，3： | 0 |
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