|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 2 | Interferon-c and interleukin-4 detected in serum and saliva from patients with oral lichen planus显示文摘Our previous salivary study had demonstrated an apparent T helper 2(Th2)-predominance in saliva of oral lichen planus(OLP) patients and suggested a potential of salivary interleukin-4(IL-4) as a biomarker for monitoring disease severity. To further determine the consistency of Th1/Th2 bias of OLP, this study investigated the expression profile of interferon-c(IFN-c) and IL-4 in serum and the relationship of the serum levels of these cytokines with their saliva partners. Sixty ethnic Chinese patients with OLP(40 of the erythematous/ulcerative form and 20 of the reticular form) were recruited for this study, with 40 age–sex-matched healthy volunteers as control group. IFN-c and IL-4 levels in serum and paired saliva samples were screened by enzyme-linked immunosorbent assay. OLP patient showed a low-level IFN-c but high-level IL-4 expression profile in both serum and saliva, with a lower IFN-c/IL-4 ratio. Serum IL-4 level in the erythematous/ulcerative group was significantly higher than that in the reticular group. Serum levels of IFN-c and IL-4 were significantly and positively correlated with their saliva partners. These results provided more evidence for Th2 cytokinepredominant immune imbalance in OLP, as well as the potential of IL-4 as the biomarker for monitoring severity of OLP. | Wen-Zhao Liu Ming-Jing He Long Long Dong-Liang Mu Ming-Shu Xu Xue Xing Xin Zeng Ga Liao Hong-Xia Dan Qian-Ming Chen | 2014 | International Journal of Oral Science2014，6，1： | 10 |
| 3 | Magnetic nanoparticles based cancer therapy: current status and applications显示文摘Nanotechnology holds a promising potential for developing biomedical nanoplatforms in cancer therapy. The magnetic nanoparticles, which integrate uniquely appealing features of magnetic manipulation, nanoscale heat generator, localized magnetic field and enzyme-mimics, prompt the development and application of magnetic nanoparticles-based cancer medicine. Considerable success has been achieved in improving the magnetic resonance imaging(MRI) sensitivity, and the therapeutic function of the magnetic nanoparticles should be given adequate attention. This work reviews the current status and applications of magnetic nanoparticles based cancer therapy. The advantages of magnetic nanoparticles that may contribute to improved therapeutics efficacy of clinic cancer treatment are highlighted here. | Huan Zhang Xiao Li Liu Yi Fan Zhang Fei Gao Ga Long Li Yuan He Ming Li Peng Hai Ming Fan | 2018 | Science China(Life Sciences)2018，61，4： | 8 |
| 4 | 激活β_3肾上腺素能受体恢复一氧化氮/氧化还原平衡,增强高血糖患者的内皮功能显示文摘一氧化氮与O_2^-之间的平衡紊乱(即一氧化氮/氧化还原失衡)是糖尿病引起的血管功能障碍的中心病理环节。该研究目的为在高血糖动物模型中探索β_3肾上腺素能受体(β_3adrenergic receptor,β3AR)激活能否耦合激活内皮型一氧化氮合酶(endothelial nitric oxide synthase,eNOS)。 | 刘莉 叶鹏 Karimi Galougahi K Liu CC Garcia A Gentile C Fry NA Hamilton EJ Hawkins CL Figtree GA | 2016 | 中华高血压杂志2016，24，3： | 2 |
| 5 | Centrifuge model tests on pile-reinforced slopes subjected to drawdown显示文摘Piles are generally an effective way to reduce the risk of slope failure.However,previous approaches for slope stability analysis did not consider the effect of the piles coupled with the decrease of the water level(drawdown).In this study,a series of centrifuge model tests was performed to understand the deformation and failure characteristics of slopes reinforced with various pile layouts.In the centrifuge model tests,the pile-reinforced slopes exhibited two typical failure modes under drawdown conditions:across-pile failure and through-pile failure.In the through-pile slope failure,a discontinuous slip surface was observed,implying that the assumption of the slip surface in previous stability analysis methods was unreasonable.The test results showed that drawdown led to instability of the piles in cohesive soil,as the saturated cohesive soil failed to provide sufficient constraint for piles.The slope exhibited progressive failure,from top to bottom,during drawdown.The deformation of the piles was reduced by increasing the embedment depth and row number of piles.In addition,the deformation of soils outside the piles was influenced by the piles and showed a similar distribution shape as the piles,and the similarity degree weakened as the distance from the piles increased.This study also found that the failure mechanism of unreinforced and pile-reinforced slopes induced by drawdown could be described by coupling between the deformation localization and local failure,and it revealed that pile-reinforced slopes could reduce slope deformation localization during drawdown. | Sujia Liu Fangyue Luo Ga Zhang | 2020 | Journal of Rock Mechanics and Geotechnical Engineering2020，12，6： | 2 |
| 6 | A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘 | Volinia S Calin GA Liu CG | | 0，，： | 2 |
| 7 | Role of apoptosis resistance in immune evasion and metastasis of colorectal cancer显示文摘The host immune system functions as a guardian against tumor development. It has been demonstrated that cytotoxic T lymphocyte (CTL)-mediated cytotoxic pathways function to inhibit or delay human colorectal cancer development. However, the host anti-tumor immune responses also 'edit' the tumor and select for more aggressive variants, resulting in immune evasion and tumor escape. Fas is a death receptor that mediates one of the major cytotoxic effector mechanisms of the CTLs. Fas is highly expressed in normal human colon epithelial cells but is frequently silenced in colorectal carcinoma, especially in metastatic colorectal carcinoma, suggesting that loss of Fas expression and function may be an immune evasion and tumor escape mechanism. In addition, recent studies indicated that Fas also mediates cellular proliferation signaling pathways to promote tumor development. Therefore, the death receptor Fas may not only transduce death signals to suppress tumor development but also activate cellular proliferation and the migration process to promote tumor growth and progression. Thus, understanding the mechanisms by which the Fas receptor and its associated protein complex transduces the death and survival signals may identify molecular targets for the development of therapeutic strategy to enhance the Fas-mediated death signals to increase the efficacy of cancer immunotherapy. | Kebin Liu, Department of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, United States | 2010 | World Journal of Gastrointestinal Oncology2010，2，11： | 2 |
| 8 | Insights into human CD34(+) hematopoietic stem/progenitor cells through a systematically proteomic survey coupled with transcriptome显示文摘 | Liu F Lu J Fan HH Wang ZQ Cui SJ Zhang GA Chi M Zhang X Yang PY Chen Z Han ZG | 2006 | 中国生物学文摘2006，20，5： | 2 |
| 9 | Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS) 显示文摘 | Gbadegesin R Hinkes B G Hoskins B E Vlangos C N Heerin ga S F Liu J | 2008 | Nephrol Dial Transplant2008，23，： | 1 |
| 10 | A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘 | Volinia S Calin GA Liu CG | | 0，，： | 1 |
| 11 | A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘 | Volinia S Calin GA Liu CG | 2006 | Proc Natl Acad Sci USA2006，103，7： | 1 |
| 12 | The Yugoslavia prospective lead study: contributions of prenatal and postnatal lead exposure to early intelligence 显示文摘 | WASSERMAN GA LIU X POPOVAC D | 2000 | Neurotoxicol Teratol2000，22，6： | 1 |
| 13 | A microRNA ex- pression signature of human solid tumors defines cancer targets显示文摘 | Volinia S Calin GA Liu CG | 2006 | Proc Natl Acad Sci USA2006，103，7： | 1 |
| 14 | Heat shock:A new approach for myocardial preservation in cardiac surgery显示文摘 | Liu X Engelman RM Cordis GA | 1992 | Circulation1992，86，5： | 1 |
| 15 | A microRNA expression sig- nature of human solid tumors defines cancer gene targets 显示文摘 | Volinia S Calin GA Liu CG | 2006 | Proc Natl Acad Sci U S A2006，103，7： | 1 |
| 16 | A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘 | VOLINIA S CALIN GA LIU CG | | 0，，： | 1 |
| 17 | A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘 | Volinia S Calin GA Liu CG | 2006 | Proc Natl Acad Sci U S A2006，103，7： | 1 |
| 18 | A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘 | Volinia S Calin GA Liu CG | 2006 | Proc Natl Acad Sci USA2006，103，13： | 1 |
| 19 | A micro RNA expression signature of human solid tumors defines cancer gene targets显示文摘 | Volinia S Calin GA Liu CG | 2006 | Proc Natl Acad Sci U S A2006，103，7： | 1 |
| 20 | A microRNA expression signature of human solid tumors defines cancer gene targets显示文摘 | Volinia S Calin GA Liu CG | 2006 | Proc Natl Acad Sci USA2006，103，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员