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| 1 | Human papilloma virus and esophageal carcinoma in a Latin-American region显示文摘AIM:To investigate the presence of high-risk human papilloma virus (HPV) in esophageal squamous cell carcinomas (ESCCs) in a non-selected Mexican population.METHODS: Cases with a pathological diagnosis of squamous cell carcinoma of the esophagus were obtained from Department of Pathology files, at the National Cancer Institute in Mexico City during the period between 2000 and 2008. Slides from each case were reviewed and cases with sufficient neoplastic tissue were selected for molecular analysis. DNA was extracted from paraffin-embedded tissue samples for polymerase chain reaction analysis to detect HPV DNA sequences. Demographic and clinical data of each patient were retrieved from corresponding clinical records.RESULTS: HPV was detected in 15 (25%) of ESCCs. HPV-16 was the most frequently observed genotype, followed by HPV-18; HPV-59 was also detected in one case. Unfortunately, HPV genotype could not be established in three cases due to lack of material for direct sequencing, although universal primers detected the presence of HPV generic sequences. No low-risk HPV genotypes were found nor was HPV-16/18 co-infection. HPV presence in ESCC was not significantly associated with gender, age, alcohol consumption, smoking, anatomic location, or histologic grade. All patients belonged to low and very low socioeconomic strata, and were diagnosed at advanced disease stage. Male patients were most commonly affected and the male:female ratio in HPV-positive ESCC increased two- fold in comparison with HPV-negative cases (6.5:1 vs 3.1:1).CONCLUSION: High prevalence of high-risk HPV in ESCC in Mexico does not support the hypothesis that HPV-associated ESCC is more common in areas with higher ESCC incidence rates. | Roberto Herrera-Goepfert Marcela Lizano Suminori Akiba Adela Carrillo-García Mauricio Becker-D'Acosta | 2009 | World Journal of Gastroenterology2009，15，25： | 4 |
| 2 | In vitro and in vivo study of glutamate dehydrogenase encapsulated into mouse erythrocyte by a hypotonic dialysis procedure显示文摘 | Sanz S Lizano C Luque J | 1999 | Life Sci1999，65，26： | 2 |
| 3 | Colon carcinoma in children and adolescents: prognostic factors and outcome—a review of 11 cases显示文摘 | Sonia Salas-Valverde Andrea Lizano Yessica Gamboa Sergio Vega Max Barrantes Silvia Santamaría Jose Barrantes Zamora | 2009 | Pediatric Surgery International2009，，12： | 1 |
| 4 | Mouse erthrocytes as carriers for coencapsulated alcohol and aldehyde dehydrogenase obtained by electroporation in vivo surviva rate in circulation, organ distribution and ethanol degradation 显示文摘 | Lizano C Perez T Pinilla M | 2001 | Life Sceinces2001，68，： | 1 |
| 5 | High prevalence ofoncogenic human papillomavirus in the genital tract ofwomen with human immunodeficiency virus 显示文摘 | Volkow P Rubi S Lizano M | 2001 | GynecolOncol2001，82，1： | 1 |
| 6 | HPV-related Carcinogenesis: Basic Concepts, Viral Types and Vari- ants 显示文摘 | Lizano M Berumen J Garcia-Carranca A | 2009 | Arch Med Res2009，40，6： | 1 |
| 7 | Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload显示文摘 | Hedhli N Lizano P Hong C | 2008 | Am J Physiol Heart Circ Physiol2008，295，： | 1 |
| 8 | Src kinase activation by direct interaction with the integrin β cyto- plasmic domain显示文摘 | Arias-Salgado EG Lizano S Sarkar S | 2003 | Proc Nat1 Acad Sci U S A2003，100，13： | 1 |
| 9 | Src kinase activation by direct interaction with the integrin beta cytoplasmic domain 显示文摘 | ARIAS-SALGADO EG LIZANO S SARKAR S | 2003 | Proc Natl Acad Sci USA2003，100，13： | 1 |
| 10 | Flux of crab larvae in a mangrove creek in the Gulf of Nicoya, Costa Rica显示文摘 | Dittel A I Epifanio C D Lizano O | 1991 | Estuarine Coastal and Shelf Science1991，32，： | 1 |
| 11 | Frequent alterations of the beta-catenin protein in cancer of the uteriue cervix 显示文摘 | Pereira-Suarez AL Meraz MA Lizano M | 2002 | Tumour Biol2002，23，1： | 1 |
| 12 | Frequent alterations of the beta - catenin protein in cancer of the uterine cervix 显示文摘 | Meraz MA lizano M | 2002 | Tumor Biol2002，23，1： | 1 |
| 13 | Colon carcinomain children and adolescents : prognostic factors and outcome-areview of 11 cases 显示文摘 | Salas-Valverde S Lizano A Gamboa Y | 2009 | Pediatr Surg Int2009，25，12： | 1 |
| 14 | Mouse erythro- cytes as carriers for co encapsulated alcohol and aldehyde dehy- drogenate obtained by electro oration In vivo survival rate in circu- lation organ distribution and ethanol degradation显示文摘 | Carmen Lizano Teresa PM Montserrat Pinilla | 2001 | Life Sciences2001，68，： | 1 |
| 15 | Mouse erythrocytes as carriers for coencapsulated alcohol and aldehyde dehydrogenase obtained by electroporation in vivo survival rate in circulation, organ distribution and ethanol degradation显示文摘 | Lizano C Perez MT Pinilla M | 2001 | Life Sci2001，68，： | 1 |
| 16 | Mouse erthrocytes as carriers for coencapsulated alcohol and aldehyde dehydrogesase obtained by electroporation in vivo survival rate in circulation,organ distribution and ethanol degradation显示文摘 | Lizano C Perez MT Pinilla M | 2001 | Life Sciences2001，68，17： | 1 |
| 17 | Prevalence of human papillomavirus genotypes,and mucosal IgA anti-viral respon- ses in women with cervical ectopy显示文摘 | Monroy OL Aguilar C Lizano M | 2010 | J Clin Virol2010，47，1： | 1 |
| 18 | Flbulin-5/DANCE is essential for elastogenesis in vivo显示文摘 | Lizano PR Ikeda Y | 2002 | Nature2002，415，6868： | 1 |
| 19 | Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload显示文摘 | Hedhli N Lizano P Hong C | 2008 | Am JPhysiol Heart Circ Physiol2008，295，4： | 1 |
| 20 | In vitro and in vivo study of glutamate dehydrogease encapsulated into mouse erythrocytes by a hypotonic dialysis procedure 显示文摘 | Sanz S Lizano C Luque J | 1999 | Life Sciences1999，65，26： | 1 |
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