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| 1 | Genome-wide association study and genomic prediction of Fusarium ear rot resistance in tropical maize germplasm显示文摘Fusarium ear rot(FER)is a destructive maize fungal disease worldwide.In this study,three tropical maize populations consisting of 874 inbred lines were used to perform genomewide association study(GWAS)and genomic prediction(GP)analyses of FER resistance.Broad phenotypic variation and high heritability for FER were observed,although it was highly influenced by large genotype-by-environment interactions.In the 874 inbred lines,GWAS with general linear model(GLM)identified 3034 single-nucleotide polymorphisms(SNPs)significantly associated with FER resistance at the P-value threshold of 1×10^(-5),the average phenotypic variation explained(PVE)by these associations was 3%with a range from 2.33%to 6.92%,and 49 of these associations had PVE values greater than 5%.The GWAS analysis with mixed linear model(MLM)identified 19 significantly associated SNPs at the P-value threshold of 1×10^(-4),the average PVE of these associations was 1.60%with a range from 1.39%to 2.04%.Within each of the three populations,the number of significantly associated SNPs identified by GLM and MLM ranged from 25 to 41,and from 5 to 22,respectively.Overlapping SNP associations across populations were rare.A few stable genomic regions conferring FER resistance were identified,which located in bins 3.04/05,7.02/04,9.00/01,9.04,9.06/07,and 10.03/04.The genomic regions in bins 9.00/01 and 9.04 are new.GP produced moderate accuracies with genome-wide markers,and relatively high accuracies with SNP associations detected from GWAS.Moderate prediction accuracies were observed when the training and validation sets were closely related.These results implied that FER resistance in maize is controlled by minor QTL with small effects,and highly influenced by the genetic background of the populations studied.Genomic selection(GS)by incorporating SNP associations detected from GWAS is a promising tool for improving FER resistance in maize. | Yubo Liu Guanghui Hu Ao Zhang Alexander Loladze Yingxiong Hu Hui Wang Jingtao Qu Xuecai Zhang Michael Olsen Felix San Vicente Jose Crossa Feng Lin Boddupalli M.Prasanna | 2021 | The Crop Journal2021，9，2： | 3 |
| 2 | Requirement for IGF-I in epidermal growth factor-mediated cell cycle progression of mammary epithelial cells显示文摘 | Stu11 MA Richert MM Loladze AV | | 0，，05： | 1 |
| 3 | Thermal versus guanidine-induced unfolding of ubiquitin: an analysis in terms of the contributions from charge-charge interactions to pro- tein stability显示文摘 | Ibarra-Molero B Loladze V V Makhatadze G I | 1999 | Biochem1999，38，25： | 1 |
| 4 | Thermodynamic Consequences of Burial of Polar and Non-polar Amino Acid Residues in the Protein Interior显示文摘 | Vakhtang V. Loladze Dmitri N. Ermolenko George I. Makhatadze | 2002 | Journal of Molecular Biology2002，，2： | 1 |
| 5 | Dynamics of a stoichiometric discrete producer-grazer model 显示文摘 | Fan M Loladze I Kuang Y | 2005 | Journal of Difference Equations and Applications2005，11，45： | 1 |
| 6 | Epithelial-specific and stage-specific funetions of insulin-like growth factor-I during postnatal mam- mary development 显示文摘 | Loladze Aimee V Stull Malinda A Rowzee Anne M | 2006 | Endocrinology2006，147，： | 1 |
| 7 | 2004, Competition and stoichiometry: Coexistence of two predators on one prey 显示文摘 | Loladze I Kuang Y Elser J J | 2004 | Theoretical Population Biology2004，65，1： | 1 |
| 8 | Competition and stoichiometry:Coexistence of two predators on one prey显示文摘 | Loladze I Kuang Y Elser J J | 2004 | Theoretical Population Biology2004，65，： | 1 |
| 9 | Requirement for IGF- Ⅰ in epidermal growth factor-mediated cell cycle progression of mammary epithelial cells显示文摘 | Stull MA Richert MM Loladze AV | 2002 | Endocrinology2002，143，5： | 1 |
| 10 | Delayed IGF-1 administration rescues oligodendroeyte progenitors from glutamate-induced cell death and hypoxic-ischemic brain damage 显示文摘 | Wood TL Loladze V Ahieri S Gangoli N Levison SW Brywe KG | 2007 | Dev Neurosci2007，29，45： | 1 |
| 11 | Delayed IGF - 1 administration rescues oligodendroeyte progenitors from glutamate - indueed cell death and hypoxie - ischemic brain damage显示文摘 | Wood TL Loladze V Ahieri S | 2007 | Dev Neurosci2007，29，45： | 1 |
| 12 | Dynamics of a stoichiometric discrete producer-grazer model显示文摘 | FAN M LOLADZE I KUANG Y | 2005 | Journal of Difference Equations and Applications2005，11，45： | 1 |
| 13 | Thermodynamic consequences of burial of polar and non-polar amino acid residues in the protein interior显示文摘 | LOLADZE V V Ermolenko D N Makhatadze G I | 2002 | Journal of Molecular Biology2002，320，： | 1 |
| 14 | Growth factor regulation of cell cycle progression in mammary epithelial cells显示文摘 | Stull MA Rowzee AM Loladze AV | 2004 | J Mammary Gland Biol Neoplasia2004，9，1： | 1 |
| 15 | Requirement for IGF-Ⅰin epidermal growth factor-mediated cell cycle progression of mammary epithelial cells显示文摘 | Stull M A Richert M M Loladze A V | 2002 | Endocrinology2002，143，5： | 1 |
| 16 | Biodiversity, habitat area, resource growth rate and interference competition显示文摘 | Yang Kuang William F. Fagan Irakli Loladze | 2003 | Bulletin of Mathematical Biology2003，，3： | 1 |
| 17 | Rising atmospheric CO2 and human nutrition: toward globally imbalanced plant stoichiometry 显示文摘 | Loladze I | 2002 | Trends Ecol Evol2002，17，： | 1 |
| 18 | Engineering a thermostable protein via optimization of charge-charge interactions on the protein surface显示文摘 | LOLADZE V V IBARRA-MOLERO B SANCHEZ-RUIZ J M | 1999 | Biochemistry1999，38，16： | 1 |
| 19 | Rising atmospheric CO2 and human nutrition: toward globally imbalanced plant stoichiometry显示文摘 | LOLADZE I | 2002 | Trends in Ecology & Evolution2002，17，10： | 1 |
| 20 | Stoichiometry in producer-grazer systems: linking energy flow with element cycling显示文摘 | Irakli Loladze Yang Kuang Jame J Elser | 2000 | Bulletin of Mathematical Biology2000，62，： | 1 |
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