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| 1 | 胆囊癌的临床诊疗现状与挑战显示文摘胆囊癌在胃肠道癌症中位居第五位,同时它也是胆道最常见的恶性肿瘤,约占80%~95%。这种肿瘤预后不佳,总体5年生存率低于5%,平均中位生存期〈6个月。因为胆囊癌在进展时可以没有任何症状,所以早期诊断是至关重要。术前诊断为胆囊结石,而术后确诊为胆囊癌的发生率为0.5%~1.5%。如果术前怀疑患者胆囊癌,则不应通过腹腔镜手术。流行病学研究已经确定了胆囊癌的发病率有地理和种族的显著差异:美洲的印第安人高发,东南亚地区也比较高,但在美洲和世界的其他地区发病率较低。环境诱发因素在胆囊癌的发展过程中发挥关键作用,胆石症、胆道和寄生虫感染的慢性炎症是最好的例证。在过去的10年里,改进成像技术和改良根治的手术方法可改善患者的预后,并帮助延长胆囊癌患者的存活时间。对于R0切除的胆囊癌患者,其总体5年生存率为21%~69%。在将来,潜在的诊断标志物的发展将对那些种族易感性或已知胆道解剖异常的人群提供早期筛查诊断的机会。 | Mislav Raki? Leonardo Patrlj Mario Kopljar Robert Kli?ek Marijan Kolovrat Bozo Loncar Zeljko Busic 冯铁诚 | 2016 | 中国普通外科杂志2016，25，2： | 24 |
| 2 | Raman lasing and soliton mode-locking in lithium niobate microresonators显示文摘The recent advancement in lithium-niobite-on-insulator(LNOI)technology is opening up new opportunities in optoelectronics,as devices with better performance,lower power consumption and a smaller footprint can be realised due to the high optical confinement in the structures.The LNOI platform offers both largeχ(2)andχ(3)nonlinearities along with the power of dispersion engineering,enabling brand new nonlinear photonic devices and applications for the next generation of integrated photonic circuits.However,Raman scattering and its interaction with other nonlinear processes have not been extensively studied in dispersion-engineered LNOI nanodevices.In this work,we characterise the Raman radiation spectra in a monolithic lithium niobate(LN)microresonator via selective excitation of Raman-active phonon modes.The dominant mode for the Raman oscillation is observed in the backward direction for a continuous-wave pump threshold power of 20mW with a high differential quantum efficiency of 46%.We explore the effects of Raman scattering on Kerr optical frequency comb generation.We achieve mode-locked states in an X-cut LNOI chip through sufficient suppression of the Raman effect via cavity geometry control.Our analysis of the Raman effect provides guidance for the development of future chip-based photonic devices on the LNOI platform. | Mengjie Yu Yoshitomo Okawachi Rebecca Cheng Cheng Wang Mian Zhang Alexander L.Gaeta Marko Loncar | 2020 | Light(Science & Applications)2020，9，1： | 5 |
| 3 | Adverse effects reported after inductive doses of the intravenous anesthetics,thiopentone, eto- midate and propofol显示文摘 | Djordjevic B Stojiljkovic MP Loncar SD | 1999 | Vojnosanit Pregl1999，56，2： | 1 |
| 4 | Simultaneous estimation shifts at lower S/N ratios显示文摘 | DEVCIC Z LONCARIC of PSF and global frame S | 2000 | IEEE Proc Image and Signal Processing and Analysis Pula2000，2000，： | 1 |
| 5 | Star-grain rocket motor-nonsteady internal ballistics显示文摘 | LONCARIC S GREATRIX R D FAWAZ Z | 2004 | Aerospace Science and Technology2004，38，8： | 1 |
| 6 | Emerging Biomarkers in Heart Failure and Cardiac Cachexia 显示文摘 | Loncar G Omersa D Cvetinovic N | 2014 | Int J Mol Sci2014，15，23： | 1 |
| 7 | Macroeconomic legitimacy of investment in the develop -ment of golf tourism in Istria 显示文摘 | Jugovic A Grzinic J Loncar S | 2009 | Ekonomska Istrazivanja2009，22，2： | 1 |
| 8 | Cardiovascular effects of induction doses of the intravenous anesthetics, propofol, etomidate and thiopentone显示文摘 | Djordjevic B Stojiljkovic MP Loncar SD | 1999 | Vojnosanit Pregl1999，56，1： | 1 |
| 9 | Advanced oxidation processes in azo dye wastewater treatment显示文摘 | Papic S Koprivanac N Ana Loncaric Bozic | 2006 | Water Env Res2006，78，6： | 1 |
| 10 | Projections of global mortality and burden of disease from 2002 to 2030显示文摘 | Mathers CD Loncar D | 2006 | PLoS Med2006，3，： | 1 |
| 11 | Projections of global mortality and burden of disease from 2002 to 2030显示文摘 | Mathers CD Loncar D | | 0，，11： | 1 |
| 12 | Projections of global mortality and burden of disease from 2002 to 2030 显示文摘 | MATHERS CD LONCAR D | 2006 | PLoS Med2006，3，11： | 1 |
| 13 | Projections of global mortality and burden of disease from 2002 to 2030显示文摘 | Mathers CD Loncar D | 2007 | PLoS Med2007，3，11： | 1 |
| 14 | Coinduction in ambulatory anesthesia显示文摘 | Dordevic B Loncar SD Ivanovic D | 2002 | Vojnosanit Pregl2002，59，6： | 1 |
| 15 | Lowtoxicity copper corrosion inhibitors 显示文摘 | Stupnigek - Lisac E Bozic E Loncaric A | 1998 | Corrosion1998，54，9： | 1 |
| 16 | Coinduction inambulat ory anest hesia显示文摘 | Dordevic B Loncar SD Ivanovic D | 2002 | Vojnosanit Pregl2002，59，6： | 1 |
| 17 | Projections of global mortality and burden of disease from 2002 to 2030 显示文摘 | Mathers CD Loncar D | 2006 | PLoS Med2006，3，11： | 1 |
| 18 | Projections of global mortality and burden ofdisease from 2002 to 2030显示文摘 | Mathers CD Loncar D | 2006 | PLoS Med2006，3，11： | 1 |
| 19 | Second hemorrhage in patients with splenic injuries 显示文摘 | Ste(anovic B Karamarkovic A Loncar Z | 2002 | Acta Chir Iugosl2002，49，3： | 1 |
| 20 | Treatment of chlorophenols in water matrix by UV/ferrioxalate system: Part I. Key process parameter evaluation by response surface methodology显示文摘 | Hrvoje Kusic Natalija Koprivanac Ana Loncaric Bozic | 2011 | Desalination2011，，1： | 1 |
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